Analysis of Fructus Arctii from Different Regions of China by HPLC Coupled with Chemometrics Methods

• Autorzy: Liu Q. , Qin K. , Shen B. , Cai H. , Cai B.
• Języki publikacji: EN

Abstrakty

EN

To evaluate the quality of Fructus Arctii, an accurate and reliable method of high-performance liquid chromatography/diode array detection—electrospray ionization—mass spectrometry (HPLC/DAD—ESI—MS) was developed. Nine compounds, including chlorogenic acid, caffeic acid, trans-p-hydroxycinnamic acid, arctiin, arctignan A, ethyl caffeate, matairesinol, arctigenin, and lappaol B, were determined simultaneously in 19 batches of Fructus Arctii samples collected from different localities. Nineteen common peaks were identified or tentatively assigned by comparing their mass spectrometric data with reference compounds, self-established compound library, and published literatures. Also, the 19 common peaks were selected as characteristic peaks to assess the similarity of chromatographic fingerprinting of these samples. Moreover, hierarchical clustering analysis (HCA) and principal components analysis (PCA) were successfully applied to demonstrate the variability of samples. The results indicated the content of nine compounds that varied greatly among the samples, and 19 samples collected from different localities could be discriminated. Furthermore, chlorogenic acid, arctiin, and arctigenin were found to be chemical markers for evaluating the quality of Fructus Arctii.

Słowa kluczowe

EN

Fructus Arctii; fingerprint analysis; chemometric analysis

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2015
• Tom: Vol. 27, no. 4
• Strony: 697--709
• Opis fizyczny: Bibliogr. 21 poz., rys., tab.

Twórcy

autor

Liu Q.

• Engineering Center of State Ministry of Education for Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing 210023, P.R. China
• Nanjing Haichang Chinese Medicine Group Co., Ltd, Nanjing 210061, P.R. China
• Key Laboratory of State Administration of TCM for Standardization of Chinese Medicine Processing, Nanjing 210023, P.R. China

autor

Qin K.

• Engineering Center of State Ministry of Education for Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing 210023, P.R. China
• Nanjing Haichang Chinese Medicine Group Co., Ltd, Nanjing 210061, P.R. China
• Key Laboratory of State Administration of TCM for Standardization of Chinese Medicine Processing, Nanjing 210023, P.R. China

autor

Shen B.

• ngineering Center of State Ministry of Education for Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing 210023, P.R. China

autor

Cai H.

• Engineering Center of State Ministry of Education for Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing 210023, P.R. China
• Key Laboratory of State Administration of TCM for Standardization of Chinese Medicine Processing, Nanjing 210023, P.R. China

autor

Cai B.

• Engineering Center of State Ministry of Education for Chinese Medicine Processing, Nanjing University of Chinese Medicine, Nanjing 210023, P.R. China
• Nanjing Haichang Chinese Medicine Group Co., Ltd, Nanjing 210061, P.R. China
• Key Laboratory of State Administration of TCM for Standardization of Chinese Medicine Processing, Nanjing 210023, P.R. China

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