Chemical components and antidiabetic activity of essential oils obtained by hydrodistillation and three solvent extraction methods from Carthamus tinctorius L.

• Autorzy: Li L. , Wang Q. , Yang Y. , Wu G , Xin X. , Aisa H. A
• Języki publikacji: EN

Abstrakty

EN

The chemical compositions of essential oils extracted by n-hexane extract (HE), petroleum ether extract (PE), dichloromethane extract (DE), and hydrodistillation (HD) from Carthamus tinctorius L. (safflower) were analyzed by gas chromatography-mass spectrometry (GC-MS). A total of 86 compounds from four different extracts were identified, and the contents were 97.65%, 98.05%, 98.93%, and 99.68%, respectively. 6,10,14-Trimethyl-2-pentadecanone, hexadecanoic acid, methyl ester, hexadecanoic acid, 8,11-octadecadienoic acid, methyl ester, and 9,12,15-octadecatrien-1-ol were the major constituents of the extracts. The antidiabete activity was assayed in vitro by against protein tyrosine phosphatase 1B (PTP1B). The results showed that the HE exhibited the best in vitro inhibitory enzyme activity against PTP1B, which holds a good potential for treating diabetes and obesity.

Słowa kluczowe

EN

Carthamus tinctorius L. (safflower); essential oils; hydrodistillation; solvent extract; GC-MS; antidiabete activity

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2012
• Tom: Vol. 24, no. 4
• Strony: 653--665
• Opis fizyczny: Bibliogr. 35 poz., rys., tab.

Twórcy

autor

Li L.

• Chinese Academy of Sciences Key Laboratory of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry Urumqi 830011 China
• Xinjiang Medical University School of Pharmacy Urumqi 830054 China

autor

Wang Q.

• Chinese Academy of Sciences Key Laboratory of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry Urumqi 830011 China

autor

Yang Y.

• Chinese Academy of Sciences Key Laboratory of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry Urumqi 830011 China

autor

Wu G

• Xinjiang Medical University School of Pharmacy Urumqi 830054 China

autor

Xin X.

• Chinese Academy of Sciences Key Laboratory of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry Urumqi 830011 China

autor

Aisa H. A

• Chinese Academy of Sciences Key Laboratory of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry Urumqi 830011 China

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