Identyfikatory
Warianty tytułu
Języki publikacji
Abstrakty
Purpose: Abnormalities in blood vessels by virtue of complex blood flow dynamics is being supported by non-Newtonian behavior of blood. Thus it becomes a focus of research to most of the researchers. Additionally, consideration of real life patient specific model of vessel as well as patient specific inlet flow boundary condition implementation was limited in literature. Thus a thorough implementation of these considerations was done here.Method: In this work, a numerical investigation of hemodynamic flow in stenosed artery has been carried out with realistic pulsating profile at the inlet. Flow has been considered to be laminar due to arresting condition of cardiovascular state of the subject. Two non-Newtonian rheological models namely, Power Law viscosity model and Quemada viscosity model have been used. Two different patient-specific pulsatile profiles are considered at the inlet of a long stenosed artery with varying degree of stenoses from 25% to 80%. Results: Transient form of Navier-Stokes equation is solved in an axi-symmetric domain to calculate the detailed flow structure of the flow field. From the simulation data, temporal and time averaged wall shear stress, oscillatory shear index and pressure drop are calculated. Conclusions: The results demonstrate that oscillatory shear index and wall shear stresses areextensively governed by the degree of stenoses. The position and movement of recirculation bubbles are found to vary with flow Reynolds number.
Czasopismo
Rocznik
Tom
Strony
33--44
Opis fizyczny
Bibliogr. 23 poz., rys., tab., wykr.
Twórcy
autor
- Department of Biomedical Engineering, National Institute of Technology, Raipur, India
autor
- School of Bioscience and Engineering, and Department of Mechanical Engineering, Jadavpur University, India
Bibliografia
- [1] AI L., ZHANG L., DAI W., HU C., SHUNG K.K., HSIAI T.K., Real-time assessment of flow reversal in an eccentric arterial stenotic model, J. Biomech., 2010, 43, 2678–2683.
- [2] BERATILIS N., BALARAS E., PARVINIAN B., KIGER K., A numerical and experimental investigation of transitional pulsatile flow in a stenosed channel, J. Biomech. Eng., 2005, 127, 1147–1157
- [3] DRIKAKIS D., MILIONIS C., PAL S.K., SHAPIRO E., Assesment of the applicability of analytical models for blood flow prediction in reconstructive surgery, Int. J. Numerical Methods in Biomed. Eng., 2011, 27, 993–999.
- [4] IQBAL M.A., Viscoelastic blood flow through arterial stenoses – Effect of various viscosity, Int. J. Nonlinear Mech., 2012, 47, 888–894.
- [5] JOHNSTON B.M., JOHNSTON P.R., CORNEY S., KILPATRICK D., NonNewtonian blood flow in human right coronary arteries: steady state simulations, J. Biomech., 2006, 39, 1116–1128.
- [6] JINYOU Y., YANG H., Numerical simulations of nonNewtonian blood flow in human thoracic aortic dissection based on CT image, IEEE Trans. of Biomed. Eng., 2011, 978(1), 238–252.
- [7] LI Z., KLEINSTREUER C., Fluid-structure interaction effects on sac-blood pressure and wall stress in a stented aneurysms, J. Biomech. Eng., 2005, 127, 662–671.
- [8] MITTAL R., SIMMONS S.P., UDAYKUMAR H.S., Application of Large-Eddy-Simulation to the study of pulsatile flow in a modeled arterial stenosis, J. Biomech. Eng., 2001, 123, 325–332.
- [9] NEOFYTOU P., DRIKAKIS D., Effects of blood models on flow through a stenosis, Int. J. Num. Methods in Fluid, 2003, 43, 597–635.
- [10] OJHA M., Wall shear stress temporal gradient and anastomotic intimal hyperplasia, Cir. Research, 1994, 74, 1227– 1231.
- [11] ROHLF K., TENTI G., The role of Womersley number in pulsatile blood flow a theoretical study of the Casson model, J. Biomech., 2001, 34, 141–148.
- [12] SIDDIQUI S.U., VERMA M.K., MISHRA S., GUPTA R.S., Mathematical modeling of pulsatile flow of Casson’s fluid in arterial stenosis, J. Ap. Math. and Com., 2009, 210, 1–10.
- [13] TAYLOR C., HUGHES T., ZARINS C., Finite Element Modeling of Blood Flow in Arteries, Com. Meth. in Ap. Mech. and Eng., 1998, 158(1–2), 155–196.
- [14] WOMERSLEY J.R., Method for the calculation of velocity, rate of flow and viscous drag in arteries when the pressure gradient is known, J. Physiol., 1955, 127, 553–563.
- [15] WALBURN F.J., SCHNECK D.J., A constitutive equation for whole human blood, Biorheology, 1976, 13, 201–219.
- [16] KU D.N., GIDDEN D.P., ZARINS C.K., GLAGOV S., Pulsatile flow and atherosclerosis in the human carotid bifurcation: Positive correlation between plaque and low oscillating shear stress, Arteriosclerosis, 1985, 5, 293–302.
- [17] QUEMADA D., Rheology of concentrated disperse systems III. General features of the proposed non-newtonian model. Comparison with experimental data, Rheo. Acta, 1977, 17, 643– 653.
- [18] TAN F.P.P., SOLOPERTO G., BASHFORD S., WOOD N.B., THOM S., HUGHES A., XU X.Y., Analysis of flow disturbance in a stenosed carotid artery bifurcation using two-equation transitional and turbulence models, J. Biomech. Eng., 2008, 130, 1–12.
- [19] ROACHE P.J., Perspective: A method for uniform reporting of grid refinement studies, J. Fluids Eng., 1994, 116(3), 405–41.
- [20] STERN F., WILSON R.V., COLEMAN H.W., PATERSON E.G., Comprehensive approach to verication and validation of CFD simulations. Part 1. Methodology and procedures, J. Fluids Eng., 2001, 123(4), 793–802.
- [21] PATANKAR S.V., Numerical Heat Transfer and Fluid Flow, McGraw–Hill, New York 1980.
- [22] RHIE C.M., CHOW W.L., Numerical Study of the Turbulent Flow Past an Airfoil with Trailing Edge Separation, AIAA J., 1983, 21, 1525–1532.
- [23] NANDI T., CHATTOPADHYAY H., Simultaneously developing flow in microchannels under pulsating inlet flow condition, Int. J. Transp. Phen., 2012, 13, 110–120.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-215bd416-f99d-404c-bae3-478cc7bca2a5