Thermographic evaluation of experimental pleurisy induced by carrageenan and modified by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

• Autorzy: Kuropka Piotr , Dobrzyński Maciej , Tarnowska Małgorzata , Dymarek Robert , Leśków Anna , Wiglusz Rafał J.

Identyfikatory

DOI

10.5277/ABB-01330-2019-04

• Języki publikacji: EN

Abstrakty

EN

The use of a thermal imaging camera may improve the detection of changes during inflammation process propagation in animals and humans that could be caused by numerous factors like 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Methods: Rats were randomised and divided into two groups, C group, in which experimental pleural inflammatory reaction was evoked and TCDD group, in which a single dose was applied 21 days before administration of 1% carrageenan solution. Infrared thermograms were taken with a microbolometer thermal imaging camera MobIR M8. The surface temperature distribution was measured in three randomly selected animals. Results: In the analysis of correlation we found negative results between both groups. In the C group, the pleurisy was developed and allowed to develop freely. It can be observed that both the average maximum temperature and the average minimum temperature were the highest after 48 hours after injection of the 1% carrageenan in solution. In TCDD group, lowered temperature in all days of experiments was noted. However, the increase of temperature after carrageenan injection was similar. The main changes observed in the lungs were oedema, hyperemia with clot formation and changes in lung structure. Several proliferative changes in the lungs were noted. Moreover, increased number of goblet cells as well and increased release of the surfactant was observed. The activation of fibroblasts and synthesis of collagen fibers was noted. Conclusions: The TCDD administration results in the reduction of superficial temperature, which is easily detectable by thermal imaging camera that can be effectively used in monitoring the course of inflammation.

Słowa kluczowe

EN

thermography; pleurisy; TCDD; rats

PL

termografia; zapalenie opłucnej; TCDD

• Wydawca: Oficyna Wydawnicza Politechniki Wrocławskiej
• Czasopismo: Acta of Bioengineering and Biomechanics
• Rocznik: 2019
• Tom: Vol. 21, no. 3
• Strony: 23--29
• Opis fizyczny: Bibliogr. 22 poz., rys., wykr.

Twórcy

autor

Kuropka Piotr

• Department of Histology and Embriology, Wroclaw University of Environmental and Life Sciences, Wrocław, Poland

autor

Dobrzyński Maciej

• Department of Conservative Dentistry and Pedodontics, Wroclaw Medical University, Wrocław

autor

Tarnowska Małgorzata

• Department of Nervous System Diseases, Wroclaw Medical University, Poland Medical University, Wrocław

autor

Dymarek Robert

• Department of Nervous System Diseases, Wroclaw Medical University, Poland Medical University, Wrocław

autor

Leśków Anna

• Department of Nervous System Diseases, Wroclaw Medical University, Poland Medical University, Wrocław

autor

Wiglusz Rafał J.

• Institute of Low Temperature and Structure Research, Polish Academy of Sciences, Wrocław

Bibliografia

• [1] BEAMER C.A., SHEPHERD D.M., Role of the aryl hydrocarbon receptor (AhR) in lung inflammation, Seminars in Immunopathology, 2013, 35, 693–704.
• [2] BRYŁA E., DOBRZYŃSKI M., DUDEK K., JANECZEK M., SOBIECH K., KOSIOR P., LEŚKÓW A., TARNOWSKA M., KAŹMIERSKA B., WIŚNIEWSKA M., CAŁKOSIŃSKI I., Zastosowanie termografii w diagnostyce przewlekłych zębopochodnych procesów zapalnych – opis przypadku, Journal of Education, Health and Sport, 2017, 7, 360–368.
• [3] CAŁKOSIŃSKI I., DOBRZYŃSKI M., ROSIŃCZUK J., DUDEK K., CHRÓSZCZ A., FITA K., DYMAREK R., The Use of Infrared Thermography as a Rapid, Quantitative, and Noninvasive Method for Evaluation of Inflammation Response in Different Anatomical Regions of Rats, BioMed Research International, 2015, 2015, 1–9.
• [4] CAŁKOSIŃSKI I., GOSTOMSKA-PAMPUCH K., MAJDA J., LEŚKÓW A., JANECZEK M., MELNYK O.P., GAMIAN A., The Influence of α-Tocopherol on Serum Biochemical Markers During Experimentally Induced Pleuritis in Rats Exposed to Dioxin, Inflammation, 2017, 40, 913–926.
• [5] CAŁKOSIŃSKI I., ROSIŃCZUK-TONDERYS J., BAZAN J., DOBRZYŃSKI M., BRONOWICKA-SZYDEŁKO A., DZIERZBA K., The influence of dioxin intoxication on the human system and possibilities of limiting its negative effects on the environment and living organisms, Annals of Agricultural and Environmental Medicine, 2014, 21, 518–524.
• [6] CALKOSINSKI I., ROSINCZUK-TONDERYS J., DOBRZYNSKI M., PALKA L., BAZAN J., Occurrence of Disseminated Intravascular Coagulation in 2,3,7,8-Tetrachlorodibenzo-p-DioxinInduced Pneumonia in the Rat, Advances in Experimental Medicine and Biology, 2013, 283–292.
• [7] CHEN R.-J., SIAO S.-H., HSU C.-H., CHANG C.-Y., CHANG L.W., WU C.-H., LIN P., WANG Y.-J., TCDD promotes lung tumors via attenuation of apoptosis through activation of the Akt and ERK1/2 signaling pathways, PloS one, 2014, 9, e99586.
• [8] EMOND C., BIRNBAUM L.S., DEVITO M.J., Physiologically Based Pharmacokinetic Model for Developmental Exposures to TCDD in the Rat, Toxicological Sciences, 2004, 80, 115–133.
• [9] FITA K., DOBRZYŃSKI M., CAŁKOSIŃSKI I., DUDEK K., BADER-ORŁOWSKA D., Przydatność termografii w diagnostyce lekarsko-stomatologicznej – doświadczenia własne, Ann. Acad. Med. Stetin, 2007.
• [10] FRANC M.A., POHJANVIRTA R., TUOMISTO J., OKEY A.B., In vivo up-regulation of aryl hydrocarbon receptor expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in a dioxinresistant rat model, Biochemical Pharmacology, 2001, 62, 1565–1578.
• [11] GEUSAU A., SCHMALDIENST S., DERFLER K., PÄPKE O., ABRAHAM K., Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: kinetics and trials to enhance elimination in two patients, Archives of Toxicology, 2002, 76, 316–325.
• [12] GORDON C.J., GRAY L.E., MONTEIRO-RIVIERE N.A., MILLER D.B., Temperature regulation and metabolism in rats exposed perinatally to dioxin: permanent change in regulated body temperature?, Toxicology and Applied Pharmacology, 1995, 133, 172–176.
• [13] GRIGORE O., MIHAILESCU A.I., SOLOMON I., BODA D., CARUNTU C., Role of stress in modulation of skin neurogenic inflammation, Experimental and Therapeutic Medicine, 2019, 17, 997–1003.
• [14] GUERRINA N., TRABOULSI H., EIDELMAN D., BAGLOLE C., GUERRINA N., TRABOULSI H., EIDELMAN D.H., BAGLOLE C.J., The Aryl Hydrocarbon Receptor and the Maintenance of Lung Health, International Journal of Molecular Sciences, 2018, 19, 3882.
• [15] HAKK H., DILIBERTO J.J., BIRNBAUM L.S., The effect of dose on 2,3,7,8-TCDD tissue distribution, metabolism and elimination in CYP1A2 (-/-) knockout and C57BL/6N parental strains of mice, Toxicology and Applied Pharmacology, 2009, 241, 119–126.
• [16] KIRSTEIN K., DOBRZYŃSKI M., KOSIOR P., CHRÓSZCZ A., DUDEK K., FITA K., PARULSKA O., RYBAK Z., SKALEC A., SZKLARZ M., JANECZEK M., Infrared Thermographic Assessment of Cooling Effectiveness in Selected Dental Implant Systems, BioMed Research International, 2016, 2016, 1–8.
• [17] LEIJS M., KOPPE J., OLIE K., DE VOOGT P., VAN AALDEREN W., TEN TUSSCHER G., Exposure to Environmental Contaminants and Lung Function in Adolescents – Is There a Link?, International Journal of Environmental Research and Public Health, 2018, 15, 1352.
• [18] MORALES-HERNÁNDEZ A., NACARINO-PALMA A., MORENO-MARÍN N., BARRASA E., PANIAGUA-QUIÑONES B., CATALINA-FERNÁNDEZ I., ALVAREZ-BARRIENTOS A., BUSTELO X.R., MERINO J.M., FERNÁNDEZ-SALGUERO P.M., Lung regeneration after toxic injury is improved in absence of dioxin receptor, Stem Cell Research, 2017, 25, 61–71.
• [19] SANTOSTEFANO M.J., JOHNSON K.L., WHISNANT N.A., RICHARDSON V.M., DEVITO M.J., DILIBERTO J.J., BIRNBAUM L.S., Subcellular localization of TCDD differs between the liver, lungs, and kidneys after acute and subchronic exposure: species/dose comparisons and possible mechanism, Fundamental and Applied Toxicology: Official Journal of the Society of Toxicology, 1996, 34, 265–275.
• [20] SARILL M., ZAGO M., SHERIDAN J.A., NAIR P., MATTHEWS J., GOMEZ A., ROUSSEL L., ROUSSEAU S., HAMID Q., EIDELMAN D.H., BAGLOLE C.J., The aryl hydrocarbon receptor suppresses cigarette-smoke-induced oxidative stress in association with dioxin response element (DRE)-independent regulation of sulfiredoxin 1, Free Radical Biology and Medicine, 2015, 89, 342–357.
• [21] SHILCO P., ROITBLAT Y., BUCHRIS N., HANAI J., COHENSEDGH S., FRIG-LEVINSON E., BURGER J., SHTERENSHIS M., Normative surface skin temperature changes due to blood redistribution: A prospective study, Journal of Thermal Biology, 2019, 80, 82–88.
• [22] YOSHIOKA W., TOHYAMA C., YOSHIOKA W., TOHYAMA C., Mechanisms of Developmental Toxicity of Dioxins and Related Compounds, International Journal of Molecular Sciences, 2019, 20, 617.

Uwagi

Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2020).