Evaluation of the effect of random setup errors on dose delivery in Intensity Modulated Radiotherapy

• Autorzy: Bharati Avinav , Mandal Susama Rani , Srivastava Anoop Kumar , Rastogi Madhup , Khurana Rohini , Hadi Rahat , Sapru Shantanu , Gandhi Ajeet Kumar , Mishra S.P.

Identyfikatory

DOI

10.2478/pjmpe-2020-0006

• Języki publikacji: EN

Abstrakty

EN

Aim: To conduct a study on the effect of random setup errors inpatient for dose delivery in Intensity Modulated Radiotherapy plans using Octavius 4D phantom. Materials and methods: 11 patients with cancer of H&N were selected for this study. An IMRT plan was created for each patient. The IMRT quality assurance plans were transferred to Mosaiq workstation in a linear accelerator. These plans were delivered at the reference treatment position. Subsequently, the QA plans were delivered on the Octavius 4D phantom after introducing errors in various translational and rotational directions. The setup inaccuracies introduced varied from 1 mm to 5 mm along X, Y. These setup uncertainties were then introduced along X and Y direction simultaneously in equal measures. Similarly, IMRT plans were delivered also after introducing roll and yaw rotation of 1, 2 and 3 degrees in phantom. The deviation of gamma indices at all these positions was analyzed with respect to the reference setup position. Results: The percentage of points passing the gamma acceptance criterion decrease as we increase the setup error. The change is found to be very insignificant with setup error up to 2 mm along X, Y or XY direction. Similarly, the rotational error of up to 3 degrees is found to be acceptable. Conclusions: Small setup (< 2 mm) correction in patients may not adversely affect the dose delivery. But an error of similar magnitude in 2 directions simultaneously has a much greater impact on IMRT dose delivery.

Słowa kluczowe

EN

gamma indices; random setup error; IMRT; quality assurance; dose delivery

• Wydawca: Polskie Towarzystwo Fizyki Medycznej ; De Gruyter
• Czasopismo: Polish Journal of Medical Physics and Engineering
• Rocznik: 2020
• Tom: Vol. 26, Iss. 1
• Strony: 55--60
• Opis fizyczny: Bibliogr. 13 poz., rys., tab.

Twórcy

autor

Bharati Avinav

• Department of Radiation Oncology, Lucknow, India

autor

Mandal Susama Rani

• Department of Radiotherapy, Kannauj Medical College, India

autor

Srivastava Anoop Kumar

• Department of Radiation Oncology, Lucknow, India

autor

Rastogi Madhup

• Department of Radiation Oncology, Lucknow, India

autor

Khurana Rohini

• Department of Radiation Oncology, Lucknow, India

autor

Hadi Rahat

• Department of Radiation Oncology, Lucknow, India

autor

Sapru Shantanu

• Department of Radiation Oncology, Lucknow, India

autor

Gandhi Ajeet Kumar

• Department of Radiation Oncology, Lucknow, India

autor

Mishra S.P.

• Department of Radiation Oncology, Lucknow, India

Bibliografia

• [1] Low DA, Moran JM, Dempsey JF, et al. Dosimetry tools and techniques for IMRT. Med Phys. 2011;38(3):1313-1338.
• [2] Low DA, Harms WB, Mutic S, Purdy JA. A technique for the quantitative evaluation of dose distributions. Med Phys. 1998;25(5):656-661.
• [3] González-Castaño D, Peña J, Sánchez-Doblado F, et al. The change of response of ionization chambers in the penumbra and transmission regions: Impact for IMRT verification. Med Biol Eng Comput. 2008;46(4):373-380.
• [4] Kim KH, Kim DS, Kim TH, et al. The influence of the IMRT QA set-up error on the 2D and 3D gamma evaluation method as obtained by using Monte Carlo simulations. J Korean Phys Soc. 2015;67:1859-1867.
• [5] Thilmann C, Nill S, Tücking T, et al. Correction of patient positioning errors based on in-line cone beam CTs: clinical implementation and first experiences. Radiat Oncol. 2006;1:16.
• [6] Su J, Chen W, Yang H, et al. Different setup errors assessed by weekly cone-beam computed tomography on different registration in nasopharyngeal carcinoma treated with intensity-modulated radiation therapy. Onco Targets Ther. 2015;8:2545-2553.
• [7] Xu F, Wang J, Bai S, et al. Interfractional and intrafractional setup errors in radiotherapy for tumors analyzed by cone-beam computed tomography. Chinese J Cancer. 2008;27(1):1111-1116.
• [8] Delishaj D, Ursino S, Pasqualetti F, et al. Set-up errors in head and neck cancer treated with IMRT technique assessed by cone-beam computed tomography: a feasible protocol. Radiat Oncol J. 2018;36(1):54-62.
• [9] Deveau MA, Gutiérrez AN, Mackie TR, et al. Dosimetric impact of daily setup variations during treatment of canine nasal tumors using Intensity modulated radiation therapy. Vet Radiol Ultrasound. 2010:51(1):90-96.
• [10] Zhang X, Shan G-p, Liu JP, Wang BB.. Margin evaluation of translational and rotational set-up errors in intensity modulated radiotherapy for cervical cancer. SpringerPlus. 2016;5:153.
• [11] Hong TS, Tome WA, Chappell RJ, et al. The impact of daily setup variations on head-and-neck intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys. 2005;61(3):779-788.
• [12] Dhanabalan R, Vivekanandan N, Prakash J, et al. SU-E-T-169: Characterization and Evaluation of Octavius 4D System for Patient Specific Quality Assurance Using 3D Gamma Index Analysis in VMAT. Medical Physics. 2013;40(6Part13):243.
• [13] McKenzie EM, Balter PA, Stingo FC, et al. Reproducibility in patient‐specific IMRT QA. J Appl Clin Med Phys. 2014;15(3):241-251.

Uwagi

Opracowanie rekordu ze środków MNiSW, umowa Nr 461252 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2020).