The effect of titanium alloy modified with a-C:N:H and a-SiCxNY(H) coatings on adhesion and immune response of human osteoblast-like MG-63 cells

• Autorzy: Ścisłowska-Czarnecka A. , Menaszek E. , Kołaczkowska E. , Januś M. , Stypuła B.
• Języki publikacji: EN

Abstrakty

EN

The study was conducted in order to determine the effects of modified titanium alloy (Ti-6Al-4V) surfaces on the biological response of a human osteoblast-like cell line. MG-63 cells were cultured on disk-shaped Ti-alloys: unmodified, and covered with a-C:N:H or a-SiCxNy(H) layers. Interactions between materials and cells were examined through determination of cells adhesion and secretion of cytokines involved in the development of immune response.

Słowa kluczowe

EN

titanium alloy; a-C:N:H and a-SiCxNy(H) coatings; osteoblast-like MG-63 cells; cell adhesion; cytokines

• Wydawca: Polish Society for Biomaterials in Cracow
• Czasopismo: Engineering of Biomaterials
• Rocznik: 2008
• Tom: Vol. 11, no. 81-84
• Strony: 126--128
• Opis fizyczny: Bibliogr. 11 poz., wykr.

Twórcy

autor

Ścisłowska-Czarnecka A.

• Department of Anatomy, Academy of Physical Education, Cracow, Poland

autor

Menaszek E.

• Department of Cytobiology and Histochemistry, Jagiellonian University, Cracow, Poland

autor

Kołaczkowska E.

• Department of Evolutionary Immunobiology, Jagiellonian University, Cracow, Poland

autor

Januś M.

• Department of Technology of Ceramics and Refractories, AGH University of Science and Technology, Cracow, Poland

autor

Stypuła B.

• Department of Chemistry and Corrosion of Metals, AGH University of Science and Technology, Cracow, Poland

Bibliografia

• [1] S. Błażewicz, L. Stoch. „Biomateriały". W: „Biocybernetyka i Inżynieria Biomedyczna 2000", red. M. Nałęcz, tom 4. Akademicka Oficyna Wydawnicza EXIT, Warszawa, 2003.
• [2] J. Marciniak. „Biomateriały". Wyd. Politechniki Śląskiej, Gliwice, 2002.
• [3] T. Wierzchoń, E. Czarnowska, D. Krupa; „Inżynieria powierzchni w wytwarzaniu biomateriałów tytanowych", Oficyna Wydawnicza Politechniki Warszawskiej, Warszawa, 2004.
• [4] J.J.A.M. van Raay, P.M. Rozing et al. "Titanium in Medicine", Springer - Verlag, Berlin, Heidenberg; 2001.
• [5] E. Broitman, W. Macdonald, N. Hellgren et al. Diamond and Related Materials, 2000, 9:1984 - 1991.
• [6] B. Płytycz, M. Chadzińska. Hodowla tkanek w immunologii. W: Hodowla komórek i tkanek (red. S.Stokłosowa) Wydawnictwo Naukowe, Warszawa, 2004, 187-216.
• [7] J. Lorenzo, M Horowitz, Y. Choi. Osteoimmunology: interactions of the bone and immune system. Endocr Rev, 2008, 29, 403-30.
• [8] R.J. Schutte, L. Xie, B. Klitzman, W.M. Reichert. In vivo cytokine-associated responses to biomaterials. Biomaterials, 2008 Oct 10. [Epub ahead of print].
• [9] J. R. Bradley. TNF-mediated inflammatory disease. J Pathol, 2008, 214: 149-60.
• [10] C.L. Langrish, B.S. Mc Kenzie, N.J. Wilson, R. de Waal Malefyt, R.A. Kastelein, D.I. Cua. IL-12 and IL-23: master regulators of innate and adaptive immunity. Immunol Rev, 2004, 202: 95-105.
• [11] M.O. Li, R.A. Flavell. Contextual regulation of inflammation: a duet by transforming growth factor - beta and interleukin 10. Immunity, 2008, 28: 468-76.

Uwagi

The study was supported by research grant no. 215/ KF/2007 in the Academy of Physical Education in Cracow.