Powiadomienia systemowe
- Sesja wygasła!
Identyfikatory
Warianty tytułu
Języki publikacji
Abstrakty
The paper presents research on storing text cytogenetic tests data conducted with GTG and FISH methods for browsing and automatic processing of its string results. It presents analysis of the text cytogenetic test result and a two proposal structures of the databases (the storing data and the analytical one) used for anonymised text GTG and FISH cytogenetic test results storing and their processing. Presented structures were queried with known chromosome aberrations for T-cell acute lymphoblastic leukaemia (T-ALL), B-cell acute lymphoblastic leukaemia (B-ALL) and both T-ALL and B-ALL in the proposed database. Additionally, the analytical database was filled with the set of Mittelman database results and browsed with non-standard queries. Conducted tests demonstrated that the proposed analitical structure is useful for GTG and FISH cytogenetic test results text mining.
Rocznik
Tom
Strony
41--48
Opis fizyczny
Bibliogr. 11 poz., rys., tab.
Twórcy
autor
- Institute of Innovative Technologies EMAG, Poland, Katowice, ul. Leopolda 31
autor
- Institute of Innovative Technologies EMAG, Poland, Katowice, ul. Leopolda 31
autor
- Institute of Innovative Technologies EMAG, Poland, Katowice, ul. Leopolda 31
Bibliografia
- [1] Atlas of Genetics and Cytogenetics in Oncology and Haematology. 2018. http://atlasgeneticsoncology.org/Anomalies/Anomliste.htmlB-ALL [Online; accessed 2018-11-02].
- [2] ABRAMS, ZACHARY B. PEABODY A. L. H. N. A., PAYNEA P. R. O. Text mining and data modeling of karyotypes to aid in drug repurposing efforts. Stud Health Technol Inform., 2015.
- [3] ABRAMS Z. B. A translational bioinformatics approach to parsing and mapping iscn karyotypes: A computational cytogenetic analysis of chronic lymphocytic leukemia (cll). 2016.
- [4] BARTLETT J. M. S. Fluorescence in situ hybridization. Molecular Diagnosis of Cancer: Methods and Protocols, 2004. Humana Press, Totowa, NJ, pp. 77–87.
- [5] EITAN, R. SHAMIR R. Reconstructing cancer karyotypes from short read data: the half empty and half full glass. BMC Bioinformatics, 2017. p. 18(1):488.
- [6] HOELZER D., GOKBUGET N., OTTMANN O., PUI C.-H., RELLING M. V., APPELBAUM F. R., VAN DONGEN J. J.,SZCZEPANSKI T. Acute lymphoblastic leukemia. ASH Education Program Book, 2002, Vol. 2002. American Society of Hematology, pp. 162–192.
- [7] JORDE, L. CAREY J. B. M. Medical genetics. 2010. MOSBY ELSEVIER.
- [8] MCGOWAN-JORDAN, J. SIMONS A. S. M. Iscn 2016 an international system for human cytogenomic nomenclature (2016) reprint of: Cytogenetic and genome research 2016. 2016. Karger Verlag.
- [9] MITELMAN F J. B., (EDS.) M. F. ”mitelman database of chromosome aberrations and gene fusions in cancer (2018). 2018. http://cgap.nci.nih.gov/Chromosomes/Mitelman [Online; accessed 2018-10-02].
- [10] SOSZYNSKA, K. MUCHA B. D. R. S. K. D. E. K. A. W. M. H. O. The application of conventional cytogenetics, fish, and rt-pcr to detect genetic changes in 70 children with all. Annals of Hematology, 2008, Vol. 87. pp. 991–1002.
- [11] SZCZEPANSKI, T. HARRISON J. V. D. C. Genetic aberrations in paediatric acute leukaemias and implications for management of patients. The lancet oncology, 2010, Vol. 11. pp. 880–9.
Uwagi
PL
Opracowanie rekordu w ramach umowy 509/P-DUN/2018 ze środków MNiSW przeznaczonych na działalność upowszechniającą naukę (2019).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-1702e923-c733-4434-8142-f4117f830204