Visualization of pathologic changes in liver tissue via polarized light

• Autorzy: Stoilova Ani , Blagoeva Blaga , Nazarova Dimana , Stoykova Elena , Berberova-Buhova Nataliya , Nedelchev Lian , Machikhin Alexander

Identyfikatory

DOI

10.37190/oa220306

• Języki publikacji: EN

Abstrakty

EN

In this work, we applied two polarized light based approaches to visualize histological patterns of liver pathologies. The first one involves acquisition of two images through a polarizing microscope, one image (P_par) acquired with the analyzer oriented parallel to the polarization of illumination and the other (P_per) acquired with the analyzer oriented perpendicular to the illumination. The final image is based on the polarization ratio, P_{reconstructed} = (P_par – P_per)/(P_par + P_per). Using the second technique, the histological specimens were illuminated with a polarized laser beam with wavelength of 635 nm. Polarimetric parameters as azimuth, angle of ellipticity, degree of polarization and reflected power have been measured to quantify the change in the polarization state of the incident light after interaction with the sample of the healthy tissue and of the tissue with abnormal morphological changes.

Słowa kluczowe

EN

polarized light imaging; tissue polarimetry; liver tissue

• Wydawca: Oficyna Wydawnicza Politechniki Wrocławskiej
• Czasopismo: Optica Applicata
• Rocznik: 2022
• Tom: Vol. 52, nr 3
• Strony: 395--404
• Opis fizyczny: Bibliogr. 19 poz., rys.

Twórcy

autor

Stoilova Ani

• Institute of Optical Materials and Technologies – Bulgarian Academy of Sciences, Acad. Georgi Bonchev Bl.109, 1113 Sofia, Bulgaria
• University of Chemical Technology and Metallurgy, Department of Physics, 8 Kl. Ohridski Blvd., 1756 Sofia, Bulgaria

autor

Blagoeva Blaga

• Institute of Optical Materials and Technologies – Bulgarian Academy of Sciences, Acad. Georgi Bonchev Bl.109, 1113 Sofia, Bulgaria

autor

Nazarova Dimana

• Institute of Optical Materials and Technologies – Bulgarian Academy of Sciences, Acad. Georgi Bonchev Bl.109, 1113 Sofia, Bulgaria

autor

Stoykova Elena

• Institute of Optical Materials and Technologies – Bulgarian Academy of Sciences, Acad. Georgi Bonchev Bl.109, 1113 Sofia, Bulgaria

autor

Berberova-Buhova Nataliya

• Institute of Optical Materials and Technologies – Bulgarian Academy of Sciences, Acad. Georgi Bonchev Bl.109, 1113 Sofia, Bulgaria

autor

Nedelchev Lian

• Institute of Optical Materials and Technologies – Bulgarian Academy of Sciences, Acad. Georgi Bonchev Bl.109, 1113 Sofia, Bulgaria
• University of Telecommunications and Post, 1 Acad. St. Mladenov Str., 1700 Sofia, Bulgaria

autor

Machikhin Alexander

• Scientific and Technological Center of Unique Instrumentation – Russian Academy of Sciences, 15 Butlerova, 117342 Moscow, Russia

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