Sensitivity analysis of transient bioheat transfer during thermal injury formation of biological tissue

• Autorzy: Jasiński M.
• Języki publikacji: EN

Abstrakty

EN

The sensitivity analysis of the transient temperature field in the 2D tissue domain with respect to its thermophysical parameters is discussed. In particular, the influence of tissue specific heat, thermal conductivity, perfusion rate and metabolic heat source on the temperature distribution is considered. In order to determine the influence of variations of these parameters on temperature distribution, the direct approach of sensitivity analysis is applied. The algorithm of modeling of tissue injury withdrawal based on Arrhenius integral is also presented. At the stage of numerical realization the boundary element method is used. In the final part of paper the results obtained are shown.

Słowa kluczowe

EN

bioheat transfer; tissue injury integral; tissue injury; sensitivity analysis

PL

przepływ ciepła; uraz tkanki; analiza wrażliwości

• Wydawca: Wydawnictwo Politechniki Częstochowskiej
• Czasopismo: Journal of Applied Mathematics and Computational Mechanics
• Rocznik: 2014
• Tom: Vol. 13, nr 2
• Strony: 33--42
• Opis fizyczny: Bibliogr. 10 poz., rys.

Twórcy

autor

Jasiński M.

• Institute of Computational Mechanics and Engineering Silesian University of Technology, Gliwice, Poland

Bibliografia

• [1] Jasiński M., Modelling of 1D bioheat transfer with perfusion coefficient dependent on tissue necrosis, Scientific Research of the Institute of Mathematics and Computer Science 2008, 7, 57-62.
• [2] Abraham J.P., Sparrow E.M., A thermal-ablation bioheat model including liquid-to-vapor phase change, pressure- and necrosis-dependent perfusion, and moisture-dependent properties, Int. Journal of Heat and Mass Transfer 2007, 50, 2537-2544.
• [3] Henriques F.C., Studies of thermal injuries, V. The predictability and the significance of thermally induced rate process leading to irreversible epidermal injury, Archives of Pathology 1947, 43, 489-502.
• [4] Jasiński M., Investigation of tissue thermal damage process with application of direct sensitivity method, MCB: Molecular & Cellular Biomechanics 2013, 10, 3, 183-199.
• [5] Mochnacki B., Majchrzak E., Sensitivity of the skin tissue on the activity of external heat sources, CMES: Computer Modeling in Engineering and Sciences 2003, 4, 3-4, 431-438.
• [6] Jasiński M., Sensitivity analysis of transient bioheat transfer with perfusion rate dependent on tissue injury, Computer Assisted Mechanics and Engineering Science 2009, 16, 267-277.
• [7] Dems K., Sensitivity analysis in thermal problems. Part I: Variation of material parameters within fixed domain, Journal of Thermal Stresses 1986, 9, 303-324.
• [8] Jasiński M., Sensitivity analysis of bioheat transfer in human cornea subjected to laser irradiation. Part 1: Variation of optical parameters, Scientific Research of the Institute of Mathematics and Computer Science 2009, 8, 63-70.
• [9] Kleiber M., Parameter Sensitivity in Nonlinear Mechanics, J.Wiley & Sons Ltd, Chichester 1997.
• [10] Majchrzak E., Application of different variants of the BEM in numerical modeling of bioheat transfer processes, MCB: Molecular & Cellular Biomechanics 2013, 10, 3, 201-232.