Saccadometry and LATER model shed light on brain plasticity in aging

• Autorzy: Coubard O. A.
• Języki publikacji: EN

Abstrakty

EN

As frequency of falls increases in older adults, understanding how motor training programs counteract motor decline is a challenging issue. This study examined ocular saccades to test the effects of fall prevention (FP) on central motor control of older fallers. Saccades were recorded using a saccadometer in twelve participants aged 64–91 years before and after 2.5-month training in FP. We performed LATER analysis enabling us to examine the changes in motor control. FP decreased saccade latency and increased left-right symmetry of motor responses. LATER analysis showed that FP modulated decisional thresholds extending our knowledge of FP influence on motor control.

Słowa kluczowe

EN

aging; motor control; eye movements; saccade; motor activity; plasticity

PL

starzenie się; ruch gałki ocznej; ruch sakadowy; aktywność ruchowa; plastyczność

• Wydawca: Nałęcz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences ; Elsevier
• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2013
• Tom: Vol. 33, no. 2
• Strony: 125--127
• Opis fizyczny: Bibliogr. 17 poz., wykr.

Twórcy

autor

Coubard O. A.

• The Neuropsychological Laboratory, CNS-Fed, 39 rue Meaux, 75019 Paris, France

Bibliografia

• [1] Nashner LM. Adapting reflexes controlling the human posture. Exp Brain Res 1976; 26: 59–72.
• [2] Rubenstein LZ. Falls in older people: epidemiology, risk factors and strategies for prevention. Age Ageing 2006; 35: ii37–41.
• [3] Robertson MC, Gardner MM, Devlin N, McGee R, Campbell AJ. Effectiveness and economic evaluation of a nurse delivered home exercise programme to prevent falls. 2. Controlled trial in multiple centres. Br Med J 2001;322: 701–4.
• [4] Benedetti MG, Berti L, Presti C, Frizziero A, Giannini S. Effects of an adapted physical activity program in a group of elderly subjects with flexed posture: clinical and instrumental assessment. J NeuroEng Rehabil 2008; 5: 32.
• [5] Judge JO. Balance training to maintain mobility and prevent disability. Am J Prev Med 2003; 25: 150–6.
• [6] Carpenter RHS. The saccadic system: a neurological microcosm. Adv Clinical Neurosci Rehabil 2004; 4: 6–8.
• [7] Carpenter RHS. Oculomotor procrastination. In: Fisher DF, Monty RA, Senders JW, (eds) Eye Movements: Cognition and Visual Perception. Hillsdale, NJ: Lawrence Erlbaum; 1981. pp. 237–246.
• [8] Carpenter RHS. A neural mechanism that randomises behaviour. J Conscious Studies 1999; 6: 13–22.
• [9] Gauchard GC, Gangloff P, Jeandel C, Perrin PP. Physical activity improves gaze and posture control in the elderly. Neurosci Res 2003; 45: 409–17.
• [10] Coubard OA. Fall prevention modulates decisional saccadic behavior in aging. Front Aging Neurosci 2012; 4: 1–20.
• [11] Ober JK, Przedpelska-Ober E, Gryncewicz W, Dylak J, Carpenter RHS, Ober JJ. Hand-held system for ambulatory measurement of saccadic durations of neurological patients. In: Gajda J, editor. Modelling and measurement in medicine. Warsaw: Komitet Biocybernetyki i Inżynierii Biomedycznej PAN; 2003. pp. 187–198.
• [12] Carpenter RHS. SPIC: a PC-based system for rapid measurement of saccadic responses. J Physiol 1994; 480: 4P.
• [13] Glickstein M, Doron K. Cerebellum: connections and functions. Cerebellum 2008; 7: 589–94.
• [14] Prsa M, Thier P. The role of the cerebellum in saccadic adaptation as a window into neural mechanisms of motor learning. Eur J Neurosci 2011; 33: 2114–28.
• [15] Goldberg ME, Musil SY, Fitzgibbon EJ, Smith M, Olson CR. The role of the cerebellum in the control of saccadic eye movements. In: Mano N, Hamada I, DeLong MR, (eds) Role of the cerebellum and basal ganglia in voluntary movement. Elsevier: Amsterdam; 1993. pp. 203–2011.
• [16] Robinson FR, Straube A, Fuchs AF. Role of the caudal fastigial nucleus in saccade generation. II. Effects of muscimol inactivation. J Neurophysiol 1993; 70: 1741–58.
• [17] Isa T, Kobayashi Y. Switching between cortical and subcortical sensorimotor pathways. Prog Brain Res 2004; 143: 299–305.