A pattern recognition approach to Emery-Dreifuss muscular dystrophy (EDMD) study

• Autorzy: Sokołowska B. , Jóźwik A. , Niebroj-Dobosz I. M. , Hausmanowa-Petrusewicz I.
• Języki publikacji: EN

Abstrakty

EN

The algorithms of pattern recognition were used for differentiation between two forms of Emery-Dreifuss muscular dystrophy (EDMD), i.e. autosomal-dominant laminopathy (AD-EDMD) and Xlinked emerynopathy (X-EDMD). A set of some matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) in serum of EDMD patients and healthy subjects were treated as features. In concluding MMPs and TIMPs levels are helpful to identifying the EDMD patients and the disease progress.

Słowa kluczowe

EN

pattern recognition; feature selection; pair-wise linear classifier; metalloproteinases and their tissue inhibitors; Emery-Dreifuss muscular dystrophy

PL

rozpoznawanie obrazów; wybór funkcji; metaloproteinaza; dystrofia mięśniowa

• Wydawca: University of Silesia, Institute of Informatics, Computer Systems Department
• Czasopismo: Journal of Medical Informatics & Technologies
• Rocznik: 2014
• Tom: Vol. 23
• Strony: 165--172
• Opis fizyczny: Bibliogr. 10 poz., rys., tab.

Twórcy

autor

Sokołowska B.

• Mossakowski Medical Research Center, Polish Academy of Sciences, Warsaw, Poland

autor

Jóźwik A.

• Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland
• Lodz University, Faculty of Physics and Applied Informatics, Lodz, Poland

autor

Niebroj-Dobosz I. M.

• Mossakowski Medical Research Center, Polish Academy of Sciences, Warsaw, Poland

autor

Hausmanowa-Petrusewicz I.

• Mossakowski Medical Research Center, Polish Academy of Sciences, Warsaw, Poland

Bibliografia

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• [8] NAGASE H., VISSE R., MURPHY G., Structure and function of matrix metalloproteinases and TIMPs, Cardiovascular Research, 2006, Vol. 69, pp. 562-573.
• [9] NIEBROJ-DOBOSZ I., MADEJ-PILARCZYK A, MARCHEL M., SOKOŁOWSKA B., HAUSMANOWAPETRUSEWICZ I., Acta Biochimica Polonica, 2009, Vol. 56 (4), pp. 717-722.
• [10] NIEBROJ-DOBOSZ I., SOKOŁOWSKA B., MADEJ-PILARCZYK A. MARCHEL M., HAUSMANOWAPETRUSEWICZ I., Tissue inhibitor of matrix metalloproteinases in serum as cardiac biomarkers in Emery-Dreifuss muscular dystrophy [Polish Heart Journal, in press].