Simultaneous determination of four major constituents in Citri Grandis Exocarpium by HPLC-DAD

• Autorzy: Yu X. X. , Liu Q. D. , Wu J. W. , Liang Z. K. , Zhao M. Q. , Xu X. J.
• Języki publikacji: EN

Abstrakty

EN

Citri Grandis Exocarpium (CGE) is a traditional Chinese medicine with a variety of biological activities. For efficient quality control of CGE, a simple, rapid, and accurate high-performance liquid chromatographic (HPLC) method was developed for simultaneous determination of four main compounds (naringin, rhoifolin, meranzin hydrate, and isoimperatorin) in this herb. These four compounds were separated on a C18 column by gradient elution with methanol and water. The flow rate was 1.0 mL•min−1, and the detection wavelength was 324 nm. The recoveries of the method ranged from 96.32% to 103.71%, and good linear relationships (r2 > 0.9998) over relative wide concentration ranges were obtained. Then this validated method was successfully applied to the analysis of nine batches of CGE samples.

Słowa kluczowe

EN

determination; Citri Grandis Exocarpium; HPLC-DAD

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2016
• Tom: Vol. 28, no. 1
• Strony: 129--143
• Opis fizyczny: Bibliogr. 16 poz., rys., tab.

Twórcy

autor

Yu X. X.

• School of Pharmaceutical Sciences, Sun Yat-Sen University, No. 132 East Waihuan Rd., Guangzhou Higher Education Mega Center, Guangzhou, 510006, China
• Guangdong Technology Research Center for Advanced Chinese Medicine, Guangzhou 510006, China

autor

Liu Q. D.

• School of Pharmaceutical Sciences, Sun Yat-Sen University, No. 132 East Waihuan Rd., Guangzhou Higher Education Mega Center, Guangzhou, 510006, China
• Guangdong Technology Research Center for Advanced Chinese Medicine, Guangzhou 510006, China

autor

Wu J. W.

• School of Pharmaceutical Sciences, Sun Yat-Sen University, No. 132 East Waihuan Rd., Guangzhou Higher Education Mega Center, Guangzhou, 510006, China
• Guangdong Technology Research Center for Advanced Chinese Medicine, Guangzhou 510006, China

autor

Liang Z. K.

• School of Pharmaceutical Sciences, Sun Yat-Sen University, No. 132 East Waihuan Rd., Guangzhou Higher Education Mega Center, Guangzhou, 510006, China
• Guangdong Technology Research Center for Advanced Chinese Medicine, Guangzhou 510006, China

autor

Zhao M. Q.

• School of Pharmaceutical Sciences, Sun Yat-Sen University, No. 132 East Waihuan Rd., Guangzhou Higher Education Mega Center, Guangzhou, 510006, China
• Guangdong Technology Research Center for Advanced Chinese Medicine, Guangzhou 510006, China

autor

Xu X. J.

• School of Pharmaceutical Sciences, Sun Yat-Sen University, No. 132 East Waihuan Rd., Guangzhou Higher Education Mega Center, Guangzhou, 510006, China
• Guangdong Technology Research Center for Advanced Chinese Medicine, Guangzhou 510006, China

Bibliografia

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Uwagi

PL

Opracowanie ze środków MNiSW w ramach umowy 812/P-DUN/2016 na działalność upowszechniającą naukę.