Early effect of thalamotomy on cognitive function in patients with Parkinson’s disease

• Autorzy: Gorzelańczyk E. J. , Ackermann-Szulgit D. , Kunc M. , Harat M. , Walecki P.

Identyfikatory

DOI

10.1515/bams-2018-0005

• Języki publikacji: EN

Abstrakty

EN

Thalamotomy is a neurosurgical procedure used in the treatment of advanced Parkinson’s disease (PD). The aim of our research is to evaluate the early impact of a lesion in the ventrointermedial nucleus (VIM) of the thalamus on cognitive and motor function in people with PD. Sixty patients who qualified for right- or leftsided VIM thalamotomy were involved in the study. The cognitive and motor functions of each patient were assessed both prior to and following the surgical procedure. Twenty-nine PD patients without ablative treatment were qualified for the comparison group, and 57 neurologically healthy individuals were assigned to the control group. The following tests were carried out: Mini Mental State Examination, Benton Visual Retention Test, Stroop Color and Word Test, Trail Making Test A&B, and Rey Auditory Verbal Learning Test. Statistically significant differences were found in reaction time, visual-spatial working memory, auditory-verbal memory, and overall level of cognitive function when comparing the results of tests carried out before and after thalamotomy and when comparing patients who had undergone surgery with untreated or healthy individuals. In patients with right-sided and left-sided thalamotomy differences were also found in the mean number of perseverative errors and recalled words.

Słowa kluczowe

EN

cognition; Parkinson's disease; stereotactic thalamotomy; ventrointermedial nucleus

• Wydawca: Uniwersytet Jagielloński - Collegium Medicum ; De Gruyter
• Czasopismo: Bio-Algorithms and Med-Systems
• Rocznik: 2018
• Tom: Vol. 14, no. 1
• Strony: art. no. 20180005
• Opis fizyczny: Bibliogr. 29 poz., tab.

Twórcy

autor

Gorzelańczyk E. J.

• Nicolaus Copernicus University Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland
• Kazimierz Wielki University, Bydgoszcz, Poland
• Non-public Health Care Center Sue Ryder Home in Bydgoszcz, Medseven, Poland

autor

Ackermann-Szulgit D.

• Kazimierz Wielki University, Bydgoszcz, Poland

autor

Kunc M.

• Airedale NHS Trust, Steeton, University of Leeds, Leeds, UK

autor

Harat M.

• Department of Neurosurgery, Military Clinical Hospital, Bydgoszcz, Poland
• Department of Public Health, Collegium Medicum, Nicolaus Copernicus, University im Toruń, Toruń, Poland

autor

Walecki P.

• Faculty of Medicine, Jagiellonian University, Medical College, Kraków, Poland

Bibliografia

• [1] Metzger CD, van der Werf YD, Walter M. Functional mapping of thalamic nuclei and their integration into cortico-striatal-thalamocortical loops via ultra-high resolution imaging-from animal anatomy to in vivo imaging in humans. Front Neurosci 2013; 7:24.
• [2] Donoso M, Collins AG, Koechlin E. Human cognition. Foundations of human reasoning in the prefrontal cortex. Science 2014; 344:1481-6.
• [3] Seidenberg M, Hermann B, Pulsipher D, Morton J, Parrish J, Geary E, et al. Thalamic atrophy and cognition in unilateral temporal lobe epilepsy. J Int Neuropsychol 2008; 14:384-93.
• [4] Saalmann YB, Kastner S. Cognitive and perceptual functions of the visual thalamus. Neuron 2011; 71:209-23.
• [5] Dupire A, Kant P, Mons N, Marchand AR, Coutureau E, Dalrymple-Alford J, et al. A role for anterior thalamic nuclei in affective cognition: interaction with environmental conditions. Hippocampus 2013; 23:392-404.
• [6] Browning PG, Chakraborty S, Mitchell AS. Evidence for mediodorsal thalamus and prefrontal cortex interactions during cognition in macaques. Cereb Cortex 2015; 25:4519-34.
• [7] Fama R, Sullivan EV. Thalamic structures and associated cognitive functions: relations with age and aging. Neurosci Biobehav Rev 2015; 54:29-37.
• [8] Schmahmann JD. Vascular syndromes of the thalamus. Stroke 2003; 34:2264-78.
• [9] Van der Werf YD, Scheltens P, Lindeboom J, Witter MP, Uylings HB, Jolles J. Deficits of memory, executive functioning and attention following infarction in the thalamus; a study of 22 cases with localised lesions. Neuropsychologia 2003; 41:1330-44.
• [10] Lagares A, de Toledo M, González-León P, Rivas JJ, Lobato RD, Ramos A, et al. Bilateral thalamic gliomas: report of a case with cognitive impairment. Rev Neurol 2004; 38:244-6.
• [11] McAlonan K, Cavanaugh J, Wurtz RH. Guarding the gateway to cortex with attention in visual thalamus. Nature 2008; 456:391-4.
• [12] Guridi J, Obeso JA, Rodriguez-Oroz MC, Lozano AA, Manrique M. L-dopa-induced dyskinesia and stereotactic surgery for Parkinson’s disease. Neurosurgery 2008; 62:311-23; discussion 323-5.
• [13] Espay AJ, Mandybur GT, Revilla FJ. Surgical treatment of movement disorders. Clin Geriatr Med 2006; 22:813-25.
• [14] Olzak M, Laskowska I, Jelonek J, Michalak M, Szolna A, Gryz J, et al. Psychomotor and executive functioning after unilateral posteroventral pallidotomy in patients with Parkinson’s disease. J Neurol Sci 2006; 248:97-103.
• [15] Nijhawan SR, Banks SJ, Aziz TZ, Panourias I, Gregory R, Yianni J, et al. Changes in cognition and health-related quality of life with unilateral thalamotomy for Parkinsonian tremor. J Clin Neurosci 2009; 16:44-50.
• [16] Tombaugh TN, McIntyre NJ. The mini-mental state examination: a comprehensive review. J Am Geriatr Soc 1992; 40:922-35.
• [17] Sivan AB. Benton Visual Retention Test®, fifth edition. 1991. [Online]. Available at: http://www.pearsonclinical.com/psychology/products/100000152/benton-visual-retention-test-fifth-edition.html. Accessed: 03 Sep 2015.
• [18] Golden C, Freshwater SM. Stroop Color & Word Test Kit for Adults and Children – Executive functioning - Neuropsychological - Psychological Testing. 2002. [Online]. Available at: http://www.stoeltingco.com/psychologicaltesting/neuropsychological/executivefunctioning/stroop-color-word-test-kit-for-adults.html. Accessed: 03 Sep 2015.
• [19] Tombaugh TN. Trail Making Test A and B: normative data stratified by age and education. Arch Clin Neuropsychol 2004; 19:203-14.
• [20] Schmidt M. Rey Auditory Verbal Learning Test™ (RAVLT™). 1996. [Online]. Available at: http://www.wpspublish.com/store/p/2933/reyauditory-verbal-learning-test-ravlt. Accessed: 03 Sep 2015.
• [21] Kane MJ, Conway AR, Miura TK, Colflesh GJ. Working memory, attention control, and the N-back task: a question of construct validity. J Exp Psychol Learn Mem Cogn 2007; 33:615-22.
• [22] Mollet GA, Harrison DW, Walters RP, Foster PS. Asymmetry in the emotional content of lateralised multimodal hallucinations following right thalamic stroke. Cogn Neuropsychiatry 2007; 12:422-36.
• [23] Gryz J, Szołna A, Harat M, Olzak M, Gorzelańczyk EJ. Early postoperative assessment of cognitive functions after stereotactic pallidotomy in patients with primary dystonia – preliminary results. Neurol Neurochir Pol 2006; 40:493-500.
• [24] Lee EY, Sen S, Eslinger PJ, Wagner D, Kong L, Lewis MM, et al. Side of motor onset is associated with hemisphere-specific memory decline and lateralized gray matter loss in Parkinson’s disease. Parkinsonism Relat Disord 2015; 21:465-70.
• [25] Okun MS, Mann G, Foote KD, Shapira NA, Bowers D, Springer U, et al. Deep brain stimulation in the internal capsule and nucleus accumbens region: responses observed during active and sham programming. J Neurol Neurosurg Psychiatry 2007; 78:310-4.
• [26] Aguiar AS, Lopes SC, Tristão FS, Rial D, de Oliveira G, da Cunha C, et al. Exercise improves cognitive impairment and dopaminę metabolism in MPTP-treated mice. Neurotox Res 2015; 29:118-25.
• [27] Braak H, Del Tredici K. Cortico-basal ganglia-cortical circuitry in Parkinson’s disease reconsidered. Exp Neurol 2008; 212:226-9.
• [28] Haber SN, Calzavara R. The cortico-basal ganglia integrative network: the role of the thalamus. Brain Res Bull 2009; 78:69-74.
• [29] Gorzelańczyk EJ. Functional anatomy, physiology and clinical aspects of basal ganglia. In: Peres JF, editor(s). Neuroimaging for clinicians combining research and practice. InTech. Available from: https://mts.intechopen.com/books/neuroimaging-for-clinicians-combiningresearch-and-practice/functional-anatomy-physiology-and-clinical-aspects-of-basal-ganglia. 2011.

Uwagi

Opracowanie rekordu w ramach umowy 509/P-DUN/2018 ze środków MNiSW przeznaczonych na działalność upowszechniającą naukę (2019).