Pulse Nebulization in Pneumatic Devices

• Autorzy: Gradoń L. , Sosnowski T. R. , Podolec Z.
• Języki publikacji: EN

Abstrakty

EN

Aerosols of a physiological salt solution and aqueous solutions of salbutamol, sodium cromoglicate, and dornase aifa were generated in a pneumatic nebulizer and analyzed in a system with controlled humidity of air as a carrier gas. Mass distribution of aerosol particles and yield of generation for pulse nebulization were measured. Pulsation of generation was realized with an attachment maintained by a computer program. Opening times of the valve were in the range 50-800 ms. The results indicate the possibility of improving aerosol particle delivery to the lung using a pulse generation system.

Słowa kluczowe

EN

inhalation; nebulizers; flow pulsation

PL

inhalacja; atomizator; aerozol fizjologiczny

• Wydawca: Taylor & Francis
• Czasopismo: International Journal of Occupational Safety and Ergonomics
• Rocznik: 1999
• Tom: Vol. 5, No. 1
• Strony: 31--42
• Opis fizyczny: Bibliogr. 6 poz., rys., tab., wykr.

Twórcy

autor

Gradoń L.

• Warsaw University of Technology, Poland

autor

Sosnowski T. R.

• Warsaw University of Technology, Poland

autor

Podolec Z.

• artmed Ltd., Poland

Bibliografia

• [1] Gradoń, L. (1997). Deposition and retention of ultrafine and fine aerosol particles in the human respiratory system. Normal and pathological cases (Abstract of an invited lecture presented at the 11th Congress of International Society for Aerosols in Medicine, Sendai, Japan). Journal of Aerosol Medicine, 10, 236.
• [2] Gradoń, L., & Podgórski, A. (1996). Deposition and retention of ultrafine and fine aerosol particles in the human respiratory system. In Proceedings of International Symposium Filtration and Separation of Fine Dust (pp. 3-14). Vienna: Working Party of Separation Processes, European Federation of Chemical Engineering.
• [3] Heinrich, U. (1995). Comparative response to long-term particle exposure among rats, mice and hamsters. Inhalation Toxicology, 8, 51-72.
• [4] Orlicki, D., & Gradoń, L. (1996). The influence of normal and pathological inhomogeneities of the lung tissues on particle transport and deposition. In J. Marijnissen & L. Gradoń (Eds.), Aerosol inhalation: Recent research frontiers (pp. 195-204). Boston: Kluwer.
• [5] Mason, J.W., & Miller, W.C. (1994). Comparison of aerosol delivery via circulaire system vs. conventional small volume nebulizer. Respiratory Care, 39, 1157-1161.
• [6] Roth, D.H., Wyzga, R.E., & Hayter, A.J. (1986). Methods and problems in estimating health risks from particulates. In S.D. Lee & T. Scheider (Eds.), Aerosols (pp. 1047-1063). Chelsea, UK: Lewis.