Simultaneous determination of eight kinds of gingerols in zingiberis rhizome collected from different areas of China

• Autorzy: Wang Y. , Chen J. , Li Y. , Li P. , Iqbal J. , Chen Y. , Ma Y. , Zhang C.

Identyfikatory

DOI

10.1556/1326.2017.00125

• Języki publikacji: EN

Abstrakty

EN

A reliable and rapid high-performance liquid chromatography coupled with diode array detector method (HPLC–DAD) was established and validated to determine eight gingerol simultaneously in the rhizomes of Zingiber offcinale Rosc. The separation of eight compounds (4-hydroxy-3-methoxy-benzenebutanol,3,5-dihydroxy-1-(4-hydroxy-3-methoxyphenyl) decane, 3,5-dihydroxy-1-(3,4-dimethoxyphenyl) decane, 6-gingerol, 8-gingerol, 6-shogaol, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-1,4-decadien-3-one, and 10-gingerol) were performed on an Agilent TC(2) C18 (250 mm × 4.6 mm, 5 μm) at 30 °C using acetonitrile (A) and 1% formic acid aqueous solution (B) as the mobile phase with gradient elution (0–10 min, 20%–35% A; 10–28 min, 35%–55% A; 28–35 min, 55%–60% A; 35–55 min, 60%–70% A; 55.01–60 min, 100%–100% A). The detection wavelength was set at 280 nm, and the flow rate was 0.8 mL/min. Validation of the analytical method was performed by linearity, precision, and accuracy test. All compounds were quantified with good linear calibration curves (coefficient of determination R2, >0.9999). The method showed good precision with overall coefficients of variation between 0.56% and 0.84%. The range of recovery was from 95.50% to 104.14% for the analytes. This method was successfully applied to quantify eight gingerols in Z. offcinale Rosc from different regions in China, so it can provide quality assessment for this medicine.

Słowa kluczowe

EN

Zingiber offcinale Rosc; gingerol; high-performance liquid chromatography; quantitative analysis

• Wydawca: University of Silesia in Katowice ; Akademiai Kiado
• Czasopismo: Acta Chromatographica
• Rocznik: 2018
• Tom: Vol. 30, no. 3
• Strony: 164--168
• Opis fizyczny: Bibliogr. 17 poz., rys.

Twórcy

autor

Wang Y.

• Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
• State Key Laboratory Breeding Base of Dao-di Herbs, China Academy of Chinese Medical Sciences, Beijing, 100700, China

autor

Chen J.

• Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China

autor

Li Y.

• Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China

autor

Li P.

• Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China

autor

Iqbal J.

• College of Life Sciences, Shenzhen University, Shenzhen, China

autor

Chen Y.

• Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China

autor

Ma Y.

• Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China

autor

Zhang C.

• Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
• State Key Laboratory Breeding Base of Dao-di Herbs, China Academy of Chinese Medical Sciences, Beijing, 100700, China

Bibliografia

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Uwagi

PL

Opracowanie rekordu w ramach umowy 509/P-DUN/2018 ze środków MNiSW przeznaczonych na działalność upowszechniającą naukę (2018).

PL

Bibliografia zgodna z oryginałem.