Multiple emulsions for simultaneous active agents delivery in a skin topical application

• Autorzy: Markowska-Radomska Agnieszka , Dluska Ewa , Metera Agata , Wojcieszak Maria

Identyfikatory

DOI

10.24425/cpe.2021.138930

• Języki publikacji: EN

Abstrakty

EN

Most antiseptic agents are intended for use on intact skin, e.g. for hand hygiene or skin preparation before any medical procedure. This paper presents multiple emulsion-based antiseptic agents as formulations for application to body surfaces with modified release rates. Multiple emulsions with a co-encapsulated antiseptic (phenyl salicylate – salol) and an agent preventing microorganism growth (benzoic acid) were formed in a Couette–Taylor flow apparatus. Results confirmed the possibility of the release kinetics modification while two compounds were encapsulated in the internal droplets of emulsions to control the release rates and time of the dose release. The addition of benzoic acid as a second active compound of the encapsulation process in the internal phase of double O1/W/O2 emulsion reduced the time necessary for the total release of salol triggering a two-step release.

Słowa kluczowe

EN

multiple emulsions; antiseptic agent; simultaneous release; co-encapsulation

PL

emulsje wielokrotne; środek antyseptyczny; jednoczesne zwolnienie; koenkapsulacja

• Wydawca: Komitet Inżynierii Chemicznej i Procesowej Polskiej Akademii Nauk
• Czasopismo: Chemical and Process Engineering
• Rocznik: 2021
• Tom: Vol. 42, nr 3
• Strony: 263--–273
• Opis fizyczny: Bibliogr. 25 poz., rys., tab.

Twórcy

autor

Markowska-Radomska Agnieszka

• Warsaw University of Technology, Faculty of Chemical and Process Engineering, Warynskiego 1, 00-645 Warsaw, Poland

autor

Dluska Ewa

• Warsaw University of Technology, Faculty of Chemical and Process Engineering, Warynskiego 1, 00-645 Warsaw, Poland

autor

Metera Agata

• Warsaw University of Technology, Faculty of Chemical and Process Engineering, Warynskiego 1, 00-645 Warsaw, Poland

autor

Wojcieszak Maria

• Warsaw University of Technology, Faculty of Chemical and Process Engineering, Warynskiego 1, 00-645 Warsaw, Poland

Bibliografia

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