Synthesis and characterization of nanostructured CaSiO3 biomaterial

• Autorzy: Jagadale P N , Kulal S R , Joshi M G , Jagtap P P , Khetre S M , Bamane S R
• Języki publikacji: EN

Abstrakty

EN

Here we report a successful preparation of nanostructured calcium silicate by wet chemical approach. The synthesized sample was characterized by various physico-chemical methods. Thermal stability was investigated using thermo-gravimetric and differential thermal analysis (TG-DTA). Structural characterization of the sample was carried out by the X-ray diffraction technique (XRD) which confirmed its single phase hexagonal structure. Transmission electron microscopy (TEM) was used to study the nanostructure of the ceramics while homogeneous grain distribution was revealed by scanning electron microscopy studies (SEM). The elemental analysis data obtained from energy dispersive X-ray spectroscopy (EDAX) were in close agreement with the starting composition used for the synthesis. Superhydrophilic nature of CaSiO3 was investigated at room temperature by sessile drop technique. Effect of porous nanosized CaSiO3 on early adhesion and proliferation of human bone marrow mesenchymal stem cells (BMMSCs) and cord blood mesenchymal stem (CBMSCs) cells was measured in vitro. MTT cytotoxicity test and cell adhesion test showed that the material had good biocompatibility and promoted cell viability and cell proliferation. It has been stated that the cell viability and proliferation are significantly affected by time and concentration of CaSiO3. These findings indicate that the CaSiO3 ceramics has good biocompatibility and that it is promising as a biomaterial.

Słowa kluczowe

EN

biomaterials; cell viability; biocompatibility; X-ray diffraction

• Wydawca: De Gruyter
• Czasopismo: Materials Science Poland
• Rocznik: 2013
• Tom: Vol. 31, No. 2
• Strony: 269--275
• Opis fizyczny: Bibliogr. 28 poz., rys., tab., wykr.

Twórcy

autor

Jagadale P N

• Department of Chemistry, Y. M. College, Bharati Vidyapeeth Deemed University, Pune-411038(MS) India

autor

Kulal S R

• Metal Oxide Research Laboratory, Department of Chemistry, Dr. Patangrao Kadam Mahavidyalaya, Sangli-416416, (MS) India

autor

Joshi M G

• Stem One, Biologicals Pvt. Ltd, 801, Urawade, Taluka–Mulashi, Pune-412 108, (MS) India

autor

Jagtap P P

• Metal Oxide Research Laboratory, Department of Chemistry, Dr. Patangrao Kadam Mahavidyalaya, Sangli-416416, (MS) India

autor

Khetre S M

• Metal Oxide Research Laboratory, Department of Chemistry, Dr. Patangrao Kadam Mahavidyalaya, Sangli-416416, (MS) India

autor

Bamane S R

• Metal Oxide Research Laboratory, Department of Chemistry, Dr. Patangrao Kadam Mahavidyalaya, Sangli-416416, (MS) India

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