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Environmental Risk Assessment of Heavy Metals in Selected Medicinal Herbs and Spices

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Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Spices and medicinal herbs is an important route for human exposure to toxic metals. This study determined total concentrations of heavy metals and risk assessment of ten types of herbs used in cooking, spices and medicinal plants available in local markets of Babylon province/Iraq. Concentrations of Cu, Ni, Zn, Pb, Co, As, Cd, Cr and Hg were estimated by ICP/Mass to identify toxic metals in the used portion of selected spices and medicinal plants. The average concentrations of these elements were within the limits allowed by the WHO. Culinary herbs and spices contained significantly Cu˃Ni˃Zn˃Pb˃Co˃As˃Cd˃Cr˃Hg. However, the concentrations of copper, zinc and nickel, respectively, were higher in all herbal samples. The study recorded the highest concentrations in the aerial parts of plants from the total elemental content of Thymus vulgaris leaves (109.4 μg·g-1). and barks of Cinnamomum verum was recorded (43 μg·g-1). Non-carcinogenic risks and estimated daily consumption of these herbs were assessed on the basis of the target hazard quotient (THQ) and Hazard Index (HI). THQ values for individual minerals were more than one indicating health risks for nickel (15.5) Mentha verticillata leaves, (12.3) for Matricaria chamomilla, other metals Cu, Co, Pb and Zn were recorded THQ˃1 which considered unsafe for human consumption. The mean Hazard Index (HI) for the nine metal elements is ˃1 for all plants except Zingiber officinale, indicating that there are non-carcinogenic risks from these nine elements. this study provides a scientific basis to guide the safe consumption of certain culinary herbs and spices, it suggest potential health concerns for consumers of these products on a daily basis over a prolonged life span.
Słowa kluczowe
Rocznik
Strony
376--384
Opis fizyczny
Bibliogr. 36 poz., rys., tab.
Twórcy
  • College of Environmental Science, Al-Qasim Green University, Al Qasim, Iraq
  • College of Environmental Science, Al-Qasim Green University, Al Qasim, Iraq
  • College of Environmental Science, Al-Qasim Green University, Al Qasim, Iraq
Bibliografia
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  • 2. Abou-Arab, A.A.K., Abou Donia, M.A. 2000. Heavy metals in Egyptian spices and medicinal plants and the effect of processing on their levels. Journal of agricultural and food chemistry, 48(6), 2300–2304.
  • 3. Bandaranayake, W.M. 2006. Quality control, screening, toxicity and regulation of herbal drugs, “in Modern Phytomedicine. Turning Medicinal Plants into Drugs, eds. Ahmad, F.Aqil, and M.Owais (Weinheim:Wiley-VCHGmbH & Co.KGaA), 25–57.
  • 4. Dghaim, R., Al Khatib, S., Rasool, H., Ali Khan, M. 2015. Determination of heavy metals concentration in traditional herbs commonly consumed in the United Arab Emirates. J Environ. Public Health, 1–6.
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  • 6. Ekor, M. 2014. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Frontiers in pharmacology, 4, 177.
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  • 8. Gao, J., Zhang, D., Uwiringiyimana, E., Proshad, R., Ugurlu, A. 2021. Evaluation of trace element contamination and health risks of medicinal herbs collected from unpolluted and polluted areas in Sichuan Province, China. Biological Trace Element Research, 199(11), 4342–4352.
  • 9. Hladun, K.R., Parker, D.R., Trumble, J.T. 2015. Cadmium, copper, and lead accumulation and bioconcentration in the vegetative and reproductive organs of Raphanus sativus: implications for plant performance and pollination. Journal of Chemical Ecology, 41(4), 386–395.
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  • 11. Jabeen, S., Shah, M.T., Khan, S., Hayat, M.Q. 2010. Determination of major and trace elements in ten important folk therapeutic plants of Haripur basin, Pakistan. J Med Plants Res, 4(7), 559–566.
  • 12. Jarup, L. 2003. Hazards of heavy metal contamination. Br Med Bull, 68(1), 167–182.
  • 13. Jawad, I. 2016. Determination of heavy metals in spices and medical herbs available on the iraq market. Adv. Environ. Biol, 10(1), 66–69.
  • 14. Kim, W.I., Noh, H.M., Hong, C.O., Kim, D.Y., Kim, K.R., Oh, K.S., Kim, J.Y. 2017. Identification of transition characteristics and bio-concentration factors of heavy metal (loid) s in the selected perennial root medicinal plants. Korean Journal of Soil Science and Fertilizer, 50(4), 251–258.
  • 15. Kohzadi, S., Shahmoradi, B., Ghaderi, E., Loqmani, H., Maleki, A. 2019. Concentration, source, and potential human health risk of heavy metals in the commonly consumed medicinal plants. Biological trace element research, 187(1), 41–50.
  • 16. Kulhari, A., Sheorayan, A., Bajar, S., Sarkar, S., Chaudhury, A., Kalia, R.K. 2013. Investigation of heavy metals in frequently utilized medicinal plants collected from environmentally diverse locations of north western India. Springer Plus, 2(1), 1.
  • 17. Li, X., Kong, D., Wang, R. 2019. Safety evaluation of heavy metals contaminated Xiaochaihu Tang using health risk. China J. Chin. Mater. Med., 93, 121–129.
  • 18. Luo, L., Wang, B., Jiang, J., Fitzgerald, M., Huang, Q., Yu, Z., Li, H., Zhang, J., Wei, J., Yang, C., Zhang, H., Dong, L., Chen, S. 2021. Heavy Metal Contaminations in Herbal Medicines: Determination, Comprehensive Risk Assessments, and Solutions. Front. Pharmacol., 11, 595335.
  • 19. Mahan, L., Escott Stump, S., Raymond, J. 2012. Krause’s food & the nutrition care process, (Krause’s Food & Nutrition Therapy). Philadelphia:WB Saunders. Materials. Geneva, Switzerland.
  • 20. Maobe, M.A., Gatebe, E., Gitu, L., Rotich, H. 2012. Profile of heavy metals in selected medicinal plants used for the treatment of diabetes, malaria and pneumonia in Kisii region, southwest Kenya. Glob J Pharmacol, 6(3), 245–251.
  • 21. Meng, C., Wang, P., Hao, Z., Gao, Z., Li, Q., Gao, H., Feng, F. 2022. Ecological and health risk assessment of heavy metals in soil and Chinese herbal medicines. Environmental geochemistry and health, 44(3), 817–828.
  • 22. Milošević, T., Đurić, M., Milošević, N. 2014. Accumulation of heavy metals in flowers of fruit species. Water, Air, Soil Pollution, 225(8), 1–8.
  • 23. Obi, E., Akunyili, D.N., Ekpo, B. 2006. Heavy metal hazards of Nigerian herbal remedies. Sci. Total Environ., 369, 35–41.
  • 24. Ozyigit, I.I., Karahan, F., Yalcin, I.E., Hocaoglu-Ozyigit, A., Ilcim, A. 2022. Heavy metals and trace elements detected in the leaves of medicinal plants collected in the southeast part of Turkey. Arabian Journal of Geosciences, 15(1), 1–21.
  • 25. Raouf, A.L.M, Hammud, K.K., Zamil, S.K. 2014. Macro-and trace metals in three medicinal herbs collected from Baghdad, Iraq market. Int J Pharm Sci Res, 5(11), 799–802.
  • 26. Sarma, H., Deka, S., Deka, H., Saikia, R.R. 2012. Accumulation of heavy metals in selected medicinal plants. Reviews of environmental contamination and toxicology, 63–86.
  • 27. Sharma, S., Nagpal, A.K., Kaur, I. 2018. Heavy metal contamination in soil, food crops and associated health risks for residents of Ropar wetland, Punjab, India and its environs. Food Chem., 255, 15–22.
  • 28. Sohrabi, M., Beigmohammadi, Z., Cheraghi, M., Majidifar, S., Jahangard, A. 2015. Health risks of heavy metals for population via consumption of greenhouse vegetables in Hamadan, Iran. Arch.Hyg. Sci. 4(4), 165–171.
  • 29. Ur Rehman, Z., Khan, S., Tahir Shah, M., Brusseau, M.L., Akbar Khan, S., Mainhagu, J. 2018. Transfer of heavy metals from soils to vegetables and associated human health risks at selected sites in Pakistan. Pedosphere, 28(4), 666–679.
  • 30. USEPA, Guidelines for the health risk assessment of chemical mixtures. (1986). Fed. Regist., 51, 34014–34025.
  • 31. Wang, J., Hansen, E.H. 2004. Online sample pretreatment Schemes for trace level determinations of metals by coupling flow injection or Sequential injection with ICP-Ms. Chem.Inform., 35, 836–846.
  • 32. Wali Alwan, S. 2022. Potential human health risk of some heavy metals in the commercially tea leaves and tea infusion. Caspian Journal of Environmental Sciences, 20(3), 629–635.
  • 33. WHO. 2002. Traditional Medicine Strategy (2002–2005).WHO/EDM/TRM/2002.1. Geneva, Switzerland: World Health Organization.
  • 34. WHO. 2004. WHO Guidelines on Safety Monitoring of Herbal Medicines in Pharmacovigilance Systems. Geneva, Switzerland: World Health Organization.
  • 35. World Health Organization. 2007. WHO guidelines for assessing quality of herbal medicines with reference to contaminants and residues. World Health Organization.
  • 36. Zheng, L., Zhang, Q., Li, Z., Sun, R., Zhong, G. 2020. Exposure risk assessment of nine metal elements in Chongqing hotpot seasoning. RSC advances, 10(4), 1971–1980.
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-04138fd5-a52a-4700-ac89-0ac5f2ac736b
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