Microwave assisted synthesis of 2,5-distyryl-1,3,4-oxadiazole derivatives as anti microbial agents

• Autorzy: Namera D. L. , Rathod J. B. , Maheta R. H. , Bhoya U. C.
• Języki publikacji: EN

Abstrakty

EN

A new series of 2,5-distyryl-1,3,4-oxadiazoles derivatives have been synthesized from cinnamic hydrazide on reaction with various cinnamic acid derivatives. The structures of synthesized compounds have been elucidated by spectral studies like IR, 1HNMR, Mass and also Elemental Analysis. Furthermore, all synthesized compounds were screened for in vitro anti microbial activity against the gram positive (Staphylococcus aureus, Pseudomonas aeruginosa) and gram negative (Escherichia coli) bacterial strain. In which some the compounds show potential inhibition against the test organisms.

Słowa kluczowe

EN

substituted cinnamic acid; substituted 1,3,4-oxadiazoles; antimicrobial activity

• Wydawca: Przedsiębiorstwo Wydawnictw Naukowych "DARWIN"
• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2014
• Tom: Vol. 10
• Strony: 46--54
• Opis fizyczny: Bibliogr. 24 poz., tab.

Twórcy

autor

Namera D. L.

• Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot - 360005, Gujrat, India

autor

Rathod J. B.

• Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot - 360005, Gujrat, India

autor

Maheta R. H.

• Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot - 360005, Gujrat, India

autor

Bhoya U. C.

• Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot - 360005, Gujrat, India

Bibliografia

• [1] S. Chao, X. Li, S. Wang, Huaxue Yanjiu Yu Yingyong. 22(8) (2010) 1066-1071.
• [2] B. Chandrakantha, Prakash Shetty, Vijesh Nambiyar, Nishitha Isloor, Arun M. Isloor, European Journal of Medicinal Chemistry 45 (2010) 1206-1210.
• [3] Rakesh Kumar, M. Shahar Yar, A. K. Rail, Saurabh Chaturvedi, Der Pharmacia Lettre 5 (1) (2013) 366-370.
• [4] N. Jain, D. P. Pathak, P. Mishra, S. Jain, J. Iranian Chem. Soc. 6 (2009) 77.
• [5] L. Srikanth, U. Naik, R. Jadhav, N. Raghunandan, J. Rao, K. Manohar., Pharma Chemica 2(4) (2010) 231-243.
• [6] M. Bhat, M. Al-Omar, N. Siddiqui, Pharma Chemica 2(2) (2010) 1-10.
• [7] K. Sushil, V. Gupta, V. Kashaw, P. Mishra, J. Stables, N. Jain., Med. Chem. Research. 38(2) (2009) 157-159.
• [8] L. Jin, J. Chen, B. Song, Z. Chen, S. Yang, Q. Li, D. Hu, R. Xu, Bioorg. Med. Chem. Lett. 16 (2006) 5036.
• [9] Wang Bao-Lei, Li Zheng-Ming, Li Yong-Hong, Wang Su-Hua, Gaodeng Xuexia o Huaxue Xuebao 29(1) (2008) 90-94.
• [10] C. R. W. Guimaraes, D. L. Boger, W. L. Jorgensen, J. Am. Chem. Soc. 127 (2005) 17377-17384.
• [11] B. Narayana, B. V. Ashalatha,a K. K. Vijaya Raj, J. Fernandes and B. K. Sarojini, Bioorganic & Medicinal Chemistry 13 (2005) 4638-4644.
• [12] Prateek Sharma, J. Chem. Pharm. Res. 3(2) (2005) 403-423
• [13] Rolando F. Pellon, Taimirys Mamposo, Erick Godlez, Osmar Calderon, Synthetic Communications 30(20) (2000) 3769-3774.
• [14] Yin Luo, Ke-Ming Qiu, Xiang Lu, Kai Liu, Jie Fu, Hai-Liang Zhu, Bioorganic & Medicinal Chemistry 19(16) (2011) 4730-4738.
• [15] Lei Liu, W. Robert Hudgins, Sonsoles Shack, Mu Quan Yin, Dvorit Samid, International Journal of Cancer 62(3) (1995) 345-350.
• [16] Fausta Natella, Mirella Nardini, Maurizio Di Felice, Cristina Scaccini, J. Agric. Food Chem. 47(4) (1999) 1453-1459.
• [17] Mario Foti, Mario Piattelli, Maria Tiziana Baratta, Giuseppe Ruberto, J. Agric. Food Chem. 44(2) (1996) 497-501.
• [18] Kudelko A., Zieliński W., Tetrahedron Lett. 53 (2012) 76-77.
• [19] Rahul R. Tripathi, Ratnamala P. Sonawane, International Letters of Chemistry, Physics and Astronomy 10(2) (2013) 119-125.
• [20] Mallikarjun S. Yadawe, Shrishila N. Unki, Sangamesh A. Patil, International Letters of Chemistry, Physics and Astronomy 12 (2013) 94-104.
• [21] G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 5 (2014) 89-98.
• [22] V. J. Faldu, P. K. Talpara, N. H. Bhuva, P. R. Vachharajani, V. H. Shah, International Letters of Chemistry, Physics and Astronomy 6 (2014) 26-32.
• [23] Piyush B. Vekariya, Jalpa R. Pandya, Vaishali Goswami, Hitendra S. Joshi, International Letters of Chemistry, Physics and Astronomy 7 (2014) 45-52.
• [24] R. G. Vaghasiya, H. B. Ghodasara, P. R. Vachharajani, V. H. Shah, International Letters of Chemistry, Physics and Astronomy 8 (2014) 30-37.