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Separation of Cells From Plasma by Means of Ultrasonics

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Języki publikacji
EN
Abstrakty
EN
This paper presents an analysis of use of ultrasonic standing wave in cell separation from bodily fluids based on the example of erythrocyte separation from plasma. It describes movement of red blood cells in plasma under the influence of the acoustic field (whose forces result from interaction of red blood cells with plasma as the vibrating medium) and under the influence of resistance forces in Stokes’ and Oseen’s approximation. The general properties of solutions of the motion equation are given. The solutions for the parameters of the ultrasonic wave and blood cells which are interesting in terms of practical applications in medical diagnostics are discussed. Time constants of the cell transportation to the regions of stable equilibrium in the field of ultrasonic standing wave are estimated. The formulas which determine the time needed to obtain the assumed concentration increase in plasma in nodes and/or anti-nodes of the standing wave are derived.
Rocznik
Strony
357--363
Opis fizyczny
Bibliogr. 14 poz., rys., wykr.
Twórcy
  • Department of Mathematical Modeling, Faculty of Mathematics and Applied Physics, Rzeszów University of Technology, Powstańców Warszawy 8, 35-959 Rzeszów, Poland
  • Department of Physics and Medical Engineering, Faculty of Mathematics and Applied Physics, Rzeszów University of Technology, Powstańców Warszawy 8, 35-959 Rzeszów, Poland
  • Department of Physics and Medical Engineering, Faculty of Mathematics and Applied Physics, Rzeszów University of Technology, Powstańców Warszawy 8, 35-959 Rzeszów, Poland
Bibliografia
  • 1. Barnett S.B. (2000), Biophysical aspects of diagnostics ultrasound, Ultrasound in Medicine and Biology, 26, Suppl. 1, 68-70, https://doi.org/10.1016/S0301-5629(00)00168-X.
  • 2. Benes E. et al. (2003), The ultrasonic h-shape separator: harvesting of the alga spirulina platens sunder zero-gravity conditions, Proceedings of World Congress on Ultrasonics, WCU 2003, Paris, France, September 7-10, 2003, pp. 1631-1638, http://www.conforg.fr/wcu2003/procs/cd1/articles/000499.pdf.
  • 3. Benes E., Gröschl M., Radel S., Hauser C., Böhm H. (2005), New simple mathematical model for the separation performance of ultrasonic celllters, Proc. 2nd Congress of Alps – Adria Acoustics Association, 1st Congress of Acoustical Society of Croatia, June 23-24, 2005, Opatija, pp. 23-24.
  • 4. Clement G. T. ( 2004), Perspectives in clinical uses of high-intensity focused ultrasound, Ultrasonics, 42, 10, 1087-1093, doi: 10.1016/j.ultras.2004.04.003.
  • 5. Czyż H. (2003), Dispersed phase acoustics in liquid [in Polish], Publishing House Rzeszów University of Technology, Rzeszów.
  • 6. Gray H. (2008), Gray’s anatomy: the anatomical basis of clinical practice, 40th ed., Elsevier, London.
  • 7. Kozaczka E. (1988), Introduction to theory of nonlinear hydroacoustics, Naval Academy Press, Gdynia.
  • 8. Łętowska M. (2011), Medical principles of taking blood samples, separating blood components and distribution [in Polish], Institute of Hematology, Warszawa.
  • 9. Nowicki A. (2010), Ultrasonics in medicine [in Polish], IPPT PAN, Warszawa.
  • 10. Pashovkin T. N., Sadikova D. G. (2009), Cell exfoliation, separation, and concentration in the field of a standing ultrasonic wave, Acoustical Physics, 55, 4-5, 584-593, https://doi.org/10.1134/S1063771009040150.
  • 11. Sadikova D. G., Andreev A. A., Shkidchenko A. N., Pashovkin T. N. (2006), Dynamics of cells concentration in a standing ultrasonic wave, Biomedical Technology and Electronics, 8-9, 95-99.
  • 12. Śliwiński A. (2003), Ultrasonics and their application [in Polish], WNT, Warszawa.
  • 13. Strippoli P. et al. (2013), An estimation of the number of cells in the human body, Annals of Human Biology, 40, 6, 463-471, doi: 10.3109/03014460.2013.807878.
  • 14. Włoch A., Czyż H., Jasiński T. (2015), Ultrasonic methods of the cells separation in human blood, Acta Physica Polonica A, 128, 2, 234-236, doi: 10.12693/APhysPolA.128.234.
Uwagi
Opracowanie rekordu w ramach umowy 509/P-DUN/2018 ze środków MNiSW przeznaczonych na działalność upowszechniającą naukę (2019).
Typ dokumentu
Bibliografia
Identyfikator YADDA
bwmeta1.element.baztech-03132738-8079-4d80-a8e8-5ad32f3ab8c7
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