Bioactive surgical sutures

• Autorzy: Zhukovsky V.
• Języki publikacji: EN

Abstrakty

EN

Investigations carried out into the development of bioactive surgical sutures and radioactive fibres are presented. Anti-microbial surgical sutures, which for a long period provide the wound with the antibiotics settled in their structure, can be of considerable use for precautions and treatment of surgical sepsis. Simultaneously the hydrolytic influence of proteolytic enzymes on the necrotising tissues, which serve as a nutrient medium for microbes, is desirable. The anaesthetic and anticancerous properties of sutures are also of such importance. Antibiotics (such as clindamycin, gentamycin, lincomycin etc.), proteolytic enzymes (such as tripsin and pepsin), anaesthetics (such as lidocaine, novocaine, trimecaine, and pyrocaine), and anti-tumour medicaments (such as prospydin, 5-fluorocyl, sarcolysin etc.) were fixed by us separately or in different combinations onto cation-exchanging polypropylene fibres with the help of ion-exchanging bonds. A principally new type of biologically active surgical fibres is radioactive fibres which exhibit their action by the emanation of ionising radiation from radioactive isotopes fixed in the fibres' structure. Sulphur-35 isotopes emanating soft beta-rays, and phosphorus-32 isotopes emanating much harder electrons were fixed by us onto polypropylene, polyethylene terephthalate, polyamide, and polyvinyl alcohol fibres by firm covalent bonds. Biological, medical and clinical tests showed the high effectiveness of the biological active sutures developed by us, as well as that of the radioactive surgical fibres used in different forms.

Słowa kluczowe

EN

surgical sutures; anti-microbial sutures; radioactive fibres; polypropylene fibre

PL

nici chirurgiczne; nici przeciwbakteryjne; włókna radioaktywne; włókna polipropylenowe

• Wydawca: Lodz University of Technology, Faculty of Material Technologies and Textile Design
• Czasopismo: Autex Research Journal
• Rocznik: 2003
• Tom: Vol. 3, no. 1
• Strony: 41--45
• Opis fizyczny: Bibliogr. 6 poz.

Twórcy

autor

Zhukovsky V.

• Saint-Petersburg State University of Technology & Design

Bibliografia

• 1. Wolf, L. A.; Meos, A.: Fibres of special use; Moscow; p. 224; 1971.
• 2. Zhukovsky, V. A.: Polypropylene surgical threads with complex biological activity; Chemical fibres; No. 6; pp. 12-16; 1996.
• 3. Patent of Russian Federation 1241553. Surgical suture based on the polymer and the way of its production; Wolf L. A. et al.; Russian Federation; application of 14 May 1982 No. 3438592; date of registration – 30 June 1993.
• 4. Patent of Russian Federation 1241554. Surgical suture based on the polymer and the way of its production; Wolf L. A. et al.; Russian Federation; application of 14 May 1982 No. 3438592; date of registration – 30 June 1993.
• 5. Patent of Russian Federation 1776100. The way of production of biologically active surgical threads; Zhukovsky V. A. et al.; Russian Federation; application of 3 May 1990 No. 4820556; date of registration – 12 April 1993.
• 6. Certificate of authorship of the USSR No. 617960.The way of radioactivating a textile material; Wolf L. A. et al.; Russian Federation; application of 8 July 1976 No. 2383561; date of registration – 7 April 1978.