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1
Respiration affectes Polymerase III directed transcription in yeast via the RAS signaling pathway
100%
Boguta M.
Acta Biochimica Polonica
|
2006
|
tom 53
|
nr Supplement 1
2
Supresja z udziałem rybosomów na przykładzie Escherichia coli i Saccharomycenes cerevisiae
100%
Boguta M.
Postępy Mikrobiologii
|
1988
|
tom 27
|
nr 1-2
3
Rola genomu jadrowego w regulacji funkcjonowania mitochondriow Saccharomyces cerevisiae
100%
Boguta M.
Postępy Biochemii
|
1996
|
tom 42
|
nr 3
259-268
4
Priony u drozdzy i grzybow nitkowatych.
75%
Boguta M.
Postępy Biochemii
|
2000
|
tom 46
|
nr 2
108-114
5
Regulation of RNA polymerase III transcription by Maf1 protein
63%
Ciesla M. , Boguta M.
Acta Biochimica Polonica
|
2008
|
tom 55
|
nr 2
215-225
EN
Maf1 was the first protein discovered to regulate polymerase III RNA in yeast and because it is evolutionarily conserved, a Maf1 ortholog also serves to restrain transcription in mouse and human cells. Understanding the mechanism of the regulation has been made possible by recent studies showing that Maf1 is a nuclear/cytoplasmic protein whose subcellular distribution and hence negative regulation of Pol III transcription is mediated by the nutrient-sensing signaling pathways, TOR and RAS. Under stress conditions and during growth in a nonfermentable carbon source Maf1 is dephosphorylated and imported to the nucleus. In its non-phosphorylated form, Maf1 interacts with the polymerase III transcription machinery. Phosphorylation serves to locate Maf1 to the cytoplasm under favorable growth conditions, thereby preventing it from non-negatively regulating polymerase III when high levels of tRNA transcription are required. Relocation of Maf1 to the cytoplasm is dependent on Msn5, a carrier responsible for export of several other phosphoproteins out of the nucleus. The absence of Maf1-mediated control of tRNA synthesis impairs yeast viability in nonfermentable carbon sources. Moreover, in cells grown in a nonfer mentable carbon source, Maf1 regulates the levels of different tRNAs to various extents. This differential regulation may contribute to the physiological role of Maf1.
6
Prion [PSI] i jego wplyw na terminacje translacji u drozdzy Saccharomyces cerevisiae.
63%
Jakubiec M. , Boguta M.
Postępy Biochemii
|
2002
|
tom 48
|
nr 3
175-181
7
Struktura i funkcja mitochondrialnych genomów
63%
Kruszewska A. , Boguta M.
Postępy Biologii Komórki
|
1988
|
tom 15
|
nr 3
8
Wzajemna regulacja translacji mitochondrialnej i translacji cytoplazmatycznej u drozdzy Saccharomyces cerevisiae.
63%
Konopinska A. , Boguta M.
Postępy Biochemii
|
2000
|
tom 46
|
nr 4
299-308
9
Mutagenesis of single domains of Maf1, repressor of the yeast RNA polymerase III
63%
Gajda A. E. , Boguta M.
Acta Biochimica Polonica
|
2006
|
tom 53
|
nr Supplement 1
10
Bialka o wlasciwosciach prionu u drozdzy Saccharomyces cerevisiae
63%
Chacinska A. , Boguta M.
Działalność Naukowa PAN. Wybrane Zagadnienia
|
2000
|
tom 10
46-49
11
Factors involved in termination of mitochondrial translation in yeast Saccharomyces carrevisiae
63%
Kunter J. , Boguta M.
Acta Biochimica Polonica
|
2006
|
tom 53
|
nr Supplement 1
12
Geny globinowe człowieka: ich budowa i układ w chromosomach
63%
Boguta M. , Putrament A.
Postępy Biochemii
|
1984
|
tom 30
|
nr 1-2
13
Coupling of mitochondrial translation with the formation of respiratory complexes in yeast mitochondria
63%
Chacinska A. , Boguta M.
Acta Biochimica Polonica
|
2000
|
tom 47
|
nr 4
EN
In contrast to most other eukaryotic organisms, yeast can survive without respiration. This ability has been exploited to investigate nuclear genes required for expression of mitochondrial DNA. Availability of complete Saccharomyces cerevisiae genomic sequence has provided additional help in detailed molecular analysis. Seven of the eight major products encoded by mitochondrial DNA are hydrophobic subunits of respiratory complexes in the inner membrane. Localization of the translation process in the same cellular compartment ensures synthesis of mitochondrially encoded proteins near sites of their assembly into multimeric respiratory complexes. Association of mitochondrial ribosomes with the membrane is mediated by mRNA-specific translational activators, that are involved in the recognition of initation codon. The newly synthesized mitochondrial proteins are transferred to membrane by a specific export system. This review discusses the role of membrane-localized factors responsible for quality control and turnover of mitochondrially synthesized subunits as well as for assembly of respiratory complexes.
14
Terminacja translacji
51%
Boguta M. , Wiwatowska J. , Hrebenda J.
Postępy Mikrobiologii
|
2001
|
tom 40
|
nr 1
63-78
15
Content available remote The Board of Directors, Leading Firms and Sectors. An Attempt of Data Mining Based Description
51%
Karbownik K. , Boguta M. , Wrzosek M.
Roczniki Kolegium Analiz Ekonomicznych
|
2007
|
tom 17
41-62
EN
The relations between attributes describing the Board of Directors and the economic performance of a relevant company, and that of the sectors in national economy are investigated. The Principal - Agent Theory and the Game Theory cannot be used in satisfactory way to verify economic behavior arising in particular situations, because they operate on general concepts. The paper presents an attempt to reformulate this issue, taking it into account when explaining the process of operational decision making. The usual focus on what the Boards of Directors do, how their composition may affect it, and what should be done to improve their effectiveness is extended to include the issue of criteria used in Board selection process. Search for empirical regularity within director's selection process leads to learn how directors are chosen and to understanding corporate organization and governance.
16
Content available remote Influence of the Education on the Level of Unemployment in European Countries
51%
Wrzosek M. , Karbownik K. , Boguta M.
Roczniki Kolegium Analiz Ekonomicznych
|
2007
|
tom 17
101-118
EN
The results of an empirical survey on the relationship between unemployment rate and selected macroeconomic indicators are presented. The goal of the analysis was to verify the hypothesis on significant correlation of the level of unemployment and the society's level of education. In addition, an investigation on the strength of the relationship between unemployment level and education linked with labor policy was conducted. Two hypotheses were investigated. The first one states that within the group of 29 surveyed countries separate subgroups, internally coherent can be distinguished. The second hypothesis postulates that the unemployment rate depends stronger on the level of expenditures and other indicators linked to education or development than on active labor market policies.
17
The overexpression of AC19, a common subunit of RNA polymerases I and III affects autophagy in yeast
51%
Wisniewska M. , Boguta M. , Graczyk D.
Acta Biochimica Polonica
|
2018
|
tom 65
|
nr S2
18
Expression of the yeast NAM9 gene coding for mitochondrial ribosomal protein
51%
Boguta M. , Chacinska A. , Murawski M. , Szczesniak B.
Acta Biochimica Polonica
|
1997
|
tom 44
|
nr 2
EN
We studied expression of the NAM9 gene of Saccharomyces cerevisiae that was previously reported to code for a mitochondrial ribosomal protein. Increase in NAM9 gene dosage is accompanied by the increase in both mRNA and protein. The levels of the NAM9 transcript and protein are both reduced in cells growing on glucose as compared to cells growing on galactose as a carbon source. Nam9p accumulates to the same level in rho(o) and rho(+) cells. These results confirm previous data indicating diverse regulation of different mitochondrial ribosomal protein genes and suggest that expression of Nam9p is not co-ordinated with the expression of other mitochondrial ribosomal components.
19
Translational readthrough of a termination codon in the yeast mitochondrial mRNA VAR1 as a result of mutation in the release factor mRF1
51%
Claisse M. L. , Boguta M. , Zagorski W.
Acta Biochimica Polonica
|
2005
|
tom 52
|
nr 1
EN
Yeast mitochondrial DNA codes for eight major polypeptides. Translation of he mitochondrially encoded polypeptides in strains with mutated mitochondrial release factor, mRF1, was found to result in the synthesis of a novel protein, V2. Different mrf1 alleles were associated with different efficiency of V2p synthesis. Translation of V2p was enhanced by paromomycin. Comparative analysis of peptides resulting from protease digestion indicated that V2p is a derivative of Var1p. According to our hypothesis, V2p represents a readthrough product of the natural stop codon in VAR1 mRNA.
20
Induction of rye [Secale cereale L.] resistance to Fusarium culmorum
51%
Jaroszyk-Scisel J. , Boguta M. , Kurek E.
Bulletin of the Polish Academy of Sciences. Biological Sciences
|
2003
|
tom 51
|
nr 3
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