The mechanism of interaction of a new group of fungicidal compounds in the cycle of energy processes was presented. It was found that it is possible to correlate the structure of bonds with their physiological activity, which permits to plan the directions of synthesis and to limit the scope of biological research in some way.
The synthesis methods of some new compounds from the group of the acrylonitrile methylothio derivatives were described, especially the synthesis of 2-methylothio-2-amine-1-cyanoacrylonitrile. The main substrate for the synthesis was malononitrile. They demonstrate fungicidal activity against five fungi. They possessed however also negative properties: mammal toxicicity and high allergenic activity.