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EN
The computational modeling studies performed on the entire 70S bacterial ribosome and its subunits are reviewed. Computational approaches became possible with the availability of three-dimensional atomic resolution structures of the ribosomal subunits. However, due to enormous size of the system theoretical efforts to study the ribosome are few and still pose a great challenge. For example, to extend the simulation time scales to biologically relevant ones, often reduced models requiring tedious parameterization procedures need to be applied. So far modeling of the ribosome involved its electrostatic properties, internal dynamics, binding of antibiotics, polypeptide folding in the ribosome tunnel, and assembly paths of proteins in the small ribosomal subunit.
EN
A model was developed to describe the material uptake and biodeposition of bivalve Mytilus edulis. The existing blue mussel organism level models are based on contradictory assumptions and no agreement has still been found regarding the processes and environmental factors to be included into the model. A reconciliation of contradictory approaches was successfully done in the present model. Using seston concentration, seston organic content and mussel size as input data, the model is able to predict the uptake of suspended material, selection of organic particles and material allocation as pseudofaeces, ingested, assimilated fractions and faeces. The results of the model application to mussels in the south-eastern Baltic conditions are discussed.
EN
The role, basic concepts and development of bioprocess engineering have been presented. Biochemical engineers have always served as a bridge between discoveries involving enzymes, cells and biomass at the lab scale to implementation of valuable bioproducts on the commercial scale. Biochemical engineering discipline was initiated focusing on problems concerning bioreactor design and the optimisation and the purification of natural products. Nowadays, this discipline is a field undergoing a rapid change and diversification. Key concepts in transport phenomena, kinetics and thermodynamics, as well as proficiency in the application of mathematical tools in process modelling are used to bridge the gap between the intellectual potential of the gene to the manufacturing of industrial products.
EN
The overall aim of the EuroCat Project is to develop a quantifiable framework of analysis for improved planning and management of catchments by analyzing the response of coastal zones of the North, Mediterranean and Baltic Sea, to changes in fluxes of nutrients, organic and inorganic xenobiotic compounds from the European rivers and their catchments (Axios, Elbe, Humber, Po, Rhine and Vistula). These changes are a consequence of introduction a new legal regulations, schemes and socio-economic conditions in the areas of countries where these catchments are located. The scale of these changes is also dependent on biogeochemical and physical properties of the catchment and they are carried from the local to global scale. The specific goal of the VisCat program is to create a system which will be used to evaluate the environmental impacts on the Vistula river catchment and the Baltic Sea due to the change from the central economy to the market economy in Eastern and Central Europe (VisCat). The primary issue of this program is also to assess the influence of the run-off reservoir in Wloclawek (Wloclawek dam), sewage-treatment plant in Torun and Vistula river?s tributaries on reduction of sediments, plankton and other pollutants in the Vistula river. Next the impact of these local changes on the global state will be studied. Another aspect of this study area within the EuroCat-VisCat program will be estimation of socio-economic changes such as: adapting the Polish law concerning management of water resources, state, regional and local programs of activity in this area and human influence on the water and ecosystem of the Vistula catchment and the Baltic coastal zone (tourism, agriculture, industry etc.) related to directives of the European Union. Next all these results will be referred to the global situation in the whole of Europe to make a prognosis of the state and behaviour of river catchments and coastal zones in the future.
EN
Hydrological and hydrodynamic processes in Vistula estuary monitored in situ and their repre-sentation by numerical model are presented. The modelled distributions of salinity and tempera-ture from the 22nd September 1995 show acceptable agreement with measurements. Results of hydrodynamic model support observations showing the spreading of fresh water along the Gulf of Gdansk shore.
EN
Researches of sociological aspects of economic conflicts testify that informal employment of the population represents one of forms of the social and economic conflict. Informal employment depends, in turn, from set social and the economic factors influencing economic behaviour of individuals on a labour market. The analysis of factors of involving of the population in one of kinds of informal employment (in employment without official registration) allows generating social portraits of this part of the population. Social portraits of informally occupied underlie modelling of possible behaviour of the population on a labour market. Modelling of probability of involving of various layers of the population in informal employment allows to develop measures on regulation of a level of informal employment and to reduce economic contradictions between subjects of a labour market.
EN
The article presents an attempt to combine some of the links between migration and development into a model to evaluate the influence of migration on economy of sending and receiving countries and then define the factors of this kind of an influence. Developed model describes the migration influence on GDP, consumption, budget revenues and expenses, current account balance receipts and expenditures, labour force, unemployment rate. Calculation methodology with limitation for use is provided. The end of the article presents the results of calculations for Ukraine as the sending country according to the proposed model during 2010 – 2015.
EN
The paper presents a method of assessment of the long-term impact of migration on the development of population and labour force in 287 regions of Europe in 31 countries. The first stage of the study was to prepare population projections in several variants. An important issue was to address the problem of the availability and quality of data on international migration. The measurement of the impact of migration on total population and labour force was conducted by comparing the percentage changes in population and labour force obtained in various simulations. The impact on the age structure was examined by analyzing demographic and labour force dependency ratios. A method of comparing the impact of various components of population change: natural change and different categories of migration flows (extra-European migration, international migration within Europe and internal migration) was proposed. In the second part of the paper, selected results of the simulations, showing potential long-term consequences of the observed migration flows, were presented. Special attention was paid to the regional differences in the consequences.
EN
The article is a comment in a discussion on conditions concerning design and usage of macroeconomic models. Building of macromodels is determined by three elements: theory of economics, within the scope of which they are built, accessible modelling techniques, and sets of reliable numerical data. The use of macromodels results from the guidelines of economic policy, and their structure is determined by concrete current and future challenges connected with creating of strategic visions of economic development. In the article, the authors also highlight the dynamic of globalization processes which, together with the effects of the global crisis of the period 2007-2009, provide new perspectives for creators of macroeconomic models. In addition, the article provides numerous examples of model constructions and recommendations concerning utilization of model techniques in the process of making macroeconomic decisions.
EN
The main objective of the paper is to examine the role of measured competencies in the labour market outcomes in two groups of European nations (the Czech Republic, Slovakia and Poland on the one hand, and Denmark, the Netherlands and Belgium on the other) that differ not only in their long term historical development, but also in their current orientation toward innovations, labour market flexibility, the openness of tertiary education and gender equality. The results of structural modelling based on data from the PIAAC (adult competencies) project of the OECD provide strong evidence for the hypothesis that the direct positive effect of competencies on labour market outcomes (namely on wages) are stronger in innovation-oriented countries, while the transitive (Central European) countries exhibit a stronger tendency towards factors typical for a “credential society” (characterised by the stronger role of formal education and larger wage gender gaps).
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The paper presents work procedures developed within the project Centre for the Research into the Oldest History of the Middle Danube River Basin. One of the activities is a search for and testing of new methods and technologies in the areas of documentation and presentation – photography, 2D and 3D photogrammetry, 3D scanning, visualisation, modelling 3D printing. We introduced the search for archaeological sites using various kinds of historical maps, ort-photomaps, satellite images and GoogleEarth-Pro, and provided details of the procedures applied during various kinds of photogrammetric documentation (from the ground, from pilotless models, from aeroplane, or a combination). There is a short description of experience with the use of individual instruments, from scanners for archaeological finds to the LIDAR. A special attention is given to the visualisation and digital modelling of movable and immovable archaeological finds. In the final part experience with a 3D printing of archaeological features is described. The obtained data are archived in the ISAU – a newly created Information System of the Institute of Archaeology. Practical experience confirms that there is no ideal method of 3D documentation suitable for all kinds of features. The outcomes are intensively used in the research process as well as during the documentation and renewal of archaeological cultural heritage, and, last but not least, for scientific popularisation aims in exhibitions and other events.
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