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Is consumption of vegetables and fruit a protective factor against kidney cancer?

100%

Azeem K. , Tomášková H. , Horáková D. , Magnusková S. , Ševčíková J. , Janout V. , Kollárová H.

Open Medicine

2013

tom 8

nr 3

364-368

The role of vegetable and fruit consumption in the aetiology of kidney cancer was analyzed using data from a case-control study conducted in two centres in the Czech Republic between 1999 and 2003. The study comprised 300 patients with newly diagnosed, histologically confirmed kidney cancer and 335 controls. Information on dietary habits was obtained using a standardized food frequency questionnaire including 23 food items. Odds ratios (ORs) and 95% confidence intervals were calculated using logistic regression models. A strong protective effect of vegetables consumption on renal cell carcinoma risk was observed among people with high consumption of fresh vegetables (OR 0.42 95% CI (0.29–0.60)) and cooked vegetables (OR 0.71, 95% CI (0.51–1.00)). The protective role of fresh fruit was significant as crude OR 0.71, 95% CI (0.50–1.00), but after adjusting for the main risk factors no association was found (OR 1.08, 95% CI (0.71–1.64)). The protective role of pickled vegetables disappeared after adjustment for the main risk factors.

Imaging studies of kidney cancer

100%

Piotr Przyczyna P. , David Aebisher D. , Joanna Gustalik J. , Sabina Galiniak S. , Dorota Bartusik-Aebisher D. , Ewa Kaznowska E.

European Journal of Clinical and Experimental Medicine

2019

nr 4

334-337

In 2017 in the USA about 5% in men and 3% in women newly diagnosed cases of malignant tumors were kidney and renal pelvis cancer. Aim. Kidney cancer in adults includes malignant tumors derived from kidney parenchyma and renal pelvis. The dominating types are kidney parenchyma, and mainly renal cell carcinomas Material and methods. This review was performed according to systematic literature search of three major bibliographic databases (Scopus, PubMed, and Cochran). Results. Imaging studies play a very important role in kidney cancer. They allow one to assess the clinical stage, justify the extent of surgery and have an impact on the prognosis. Conclusion. The field for research involves the use of magnetic resonance and positron emission tomography in diagnosing kidney changes.

Analyzing selected risk factors for the development of kidney cancer

88%

Kollárová H. , Azeem-Skřejpková K. , Tomášková H. , Horáková D. , Magnusková S. , Janout V.

Open Medicine

2012

tom 7

nr 1

78-84

The aim of this study was to determine influence of selected lifestyle factors on kidney cancer. The study brings data from two centres of international multicentric hospital-based analytical observational case-control studies. Data were obtained from a group of 300 patients newly diagnosed with kidney cancer (ICD-O-2 code C64) and 335 controls from two centres in the Czech Republic. Results showed that smoking increased OR to 1.09 (95% CI 0.77–1.55) and 1.06 (95% CI 0.73–1.52), but the results were not statistically significant. Obesity (BMI⩾30) created adjusted OR 1.71 (95% CI 1.11–2.66) and 1.44 (95% CI 0.91–2.28), showing a minor, statistically insignificant, effect of obesity on the development of kidney cancer. For hypertension, adjusted OR was 1.73 (95% CI 1.25–2.40), suggesting a minor to moderate effect of hypertension on kidney cancer. The analysis results showed a positive association between hereditary predisposition and the development of kidney cancer with an OR of 1.97 (95% CI 1.41–2.76) and 1.97 (95% CI 1.40–2.77) depending on the model of adjustment. The reasons for the high incidence of kidney cancer are not fully understood. Genetic polymorphisms, together with other lifestyle and environmental factors, are likely to contribute to various rates of kidney cancer incidence throughout the world.