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1 2012

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Mimicking the morphology of long bone

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Ficai A. , Andronescu E. , Ficai D. , Sonmez M. , Albu M. , Voicu G.

Open Chemistry

2012

tom 10

nr 6

1949-1953

The aim of this work was to mimic the stratified structure of the median region of long bones. Starting from this desideratum, more COLL/HA composite materials with different morphology were synthesized and characterized, each of these materials mimicking one layer of long bone (endo- and periosteum, compact and cancellous bony tissue). Stratified bone grafts were obtained by assembling these layers; the obtained grafts were similar to the median region of long bones. Even though, natural bones have a more complex microstructure, this is a pioneering work since for the first time a stratified COLL/HA composite material similar to bone was produced. [...]