The own method of the pancreas cannulation was introduced and the examinations were done on two groups of pigs, 10 animals each, for 14 days. In the 1st group an operation was performed in a way to be able to collected the whole of the secreted pancreatic juice. The twenty-four hour excretion of pancreatic juice was evaluated, taking into account the dynamic of excretion depending on the time of day and meals. On the 14th day-x-ray contrast examinations were performed to evaluate the pancreatic excretory ducts, and then, after slaughter, gross lesions were estimated and the pancreas samples were collected to estimate the structure of pancreatic parenchyma. In the 2nd group, a cannula of the own construction was used to collect pancreatic juice transported into the duodenum. The whole juice was not collected to prevent disturbances in the regulatory system of excretion. The apllied system therefore enabled an uncomplicated collection of pancreatic juice and duodenal content. The identical examinations as in group 1 were done in group 2. The applied method of the pancreas cannulation appeared to be effective, technically simple and non-invasive for pancreatic parenchyma. Transportation of pancreatic juice into the duodenum eliminates its hypersecretion that is of a great value for the condition of the pancreas after the experiment.