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Coronary artery disease associated with radiation therapy

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Celık T. , Yuksel C. , Demırkol S. , Iyısoy A. , Ulutın C.

Open Medicine

2010

tom 5

nr 2

180-183

Recent advancements in curative-intent therapies have led to dramatic improvements in breast cancer-specific mortality but at the direct expense of increased risk of cardiovascular-related mortality. The use of radiation therapy has led to significant improvements in survival for patients treated for breast cancer. However, as patients live longer, the potentially serious adverse effects of radiation on the heart have raised concerns. Coronary artery disease following irradiation is encountered rarely but is one of the most devastating treatable complications.In this article we review the cardiac complications associated with radiation therapy.