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Giant iliac artery aneurysm

100%

Ugurlucan M. , Erdim F. , Alpagut U. , Tireli E. , Dayioglu E.

Open Medicine

2010

tom 5

nr 2

156-158

Isolated iliac artery aneuryms are very rare vascular malformations. They can remain unnoticed for long periods of time because of their deep location in the pelvic region. Most of the patients present to the clinic with rupture of the aneurysm, and thus the condition has a very high mortality rate. We report here the case of an 84-year-old man with giant iliac artery aneuryms who was treated successfully by aneurysmectomy and aortoiliac bypass.

Computational analysis of aortic hemodynamics during total and partial extra-corporeal membrane oxygenation and intra-aortic balloon pump support

51%

Caruzo M. V. , Gramigna V. , Renzulli A. , Fragomeni G.

Acta of Bioengineering and Biomechanics

2016

tom Vol. 18, nr 3

3--9

Purpose: The extracorporeal membrane oxygenation (ECMO) is a temporary, but prolonged circulatory support for cardiopulmonary failure. Clinical evidence suggests that pulsed flow is healthier than non pulsatile perfusion. The aim of this study was to computationally evaluate the effects of total and partial ECMO assistance and pulsed flow on hemodynamics in a patient-specific aorta model. Methods: The pulsatility was obtained by means of the intra-aortic balloon pump (IABP), and two different cases were investigated, considering a cardiac output (CO) of 5 L/min: Case A – total assistance – the whole flow delivered through the ECMO arterial cannula; Case B – partial assistance – flow delivered half through the cannula and half through the aorta. Computational fluid dynamic (CFD) analysis was carried out using the multiscale approach to couple the 3D aorta model with the lumped parameter model (resistance boundary condition). Results: In case A pulsatility followed the balloon radius change, while in case B it was mostly influenced by the cardiac one. Furthermore, during total assistance, a blood stagnation occurred in the ascending aorta; in the case of partial assistance, the flow was orderly when the IABP was on and was chaotic when the balloon was off. Moreover, the mean arterial pressure (MAP) was higher in case B. The wall shear stress was worse in ascending aorta in case A. Conclusions: Partial support is hemodynamically advisable.