Wyniki wyszukiwania - Biblioteka Nauki

1

Quality of Life and Sleep Disorders Among Patients Treated with Hemodialysis in Relation to Dialysis Adequacy

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Dryl-Rydzyńska T. , Sak J. , Książek A.

Polish Journal of Public Health

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2015

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tom 124

|

nr 3

111-114

EN

Introduction. Recent studies in this field are insufficient to determine the relationship between life quality and hemodialy-sis adequacy. The problem, which requires further analysis is the issue of verification of these relationships and the problem of the relationship between sleep disorders and hemodialysis indicators. Aim. The aim of this study is to determine the relationship between quality of life and sleep disorders occurring among patients with end stage renal disease (ESRD) treated with hemodialysis and the dialysis adequacy parameters. Material and methods. The survey was based on two standardized international scales: the Quality of Life Scale (SF-36) and the Pittsburg Sleep Quality Index (PSQI). The study was conducted among 150 patients (67 women and 83 men) treated with hemodialysis at the Fresenius center. All patients participating in the study were undergoing dialysis three times a week. The average value of Kt/V was 1.45 (SD=0.22) and URR ration 71.78 (SD=5.95). Results. The urea level prior to hemodialysis moderately strongly correlates with life energy deficit (r=-0.34, p=-0.049) and that the values of urea reduction ratio URR weakly correlates with the patient's conviction on restricting life's activity (SF-36) (r=0.18, p=0.046). The level of urea prior to dialysis correlates positively with the time of falling asleep in PSQI scale (r=-0.39, p=0.023). Conclusions. Patients with lower urea level before hemodialysis have a significantly higher vitality level. Higher fluctuations of urea concentrations before and after hemodialysis (higher urea reduction ratio URR) are associated with restrictions of physical activity in hemodialysis patients.

2

High-hydrophilic membranes for dialysis and hemodialysis

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Suberlyak O. , Melnyk J. , Baran N.

Engineering of Biomaterials

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2007

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tom Vol. 10, no. 63-64

18-19

3

Cardiac valve calcifications and predictive parameters in hemodialysis patients

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Selcoki Y. , Turgut F. , Kanbay M. , Ozkara A. , Tekin O. , Uz B. , Akcay A.

Open Medicine

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2007

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tom 2

|

nr 3

304-312

EN

Cardiac valvular calcification is frequent among hemodialysis (HD) patients. The presence of valvular calcification can help identify HD patients with a higher risk for cardiovascular diseases. Our aim was to determine the prevalence of valvular calcification (VC) in our maintenance hemodialysis (HD) population and to examine some possible etiologic factors for its occurrence. We studied forty-four patients on hemodialysis (23 women and 21 men; mean age 57 ± 18 year; mean HD duration 34 ± 28 months). Valvular calcification (VC) was observed in 21 patients (48%). Of these patients, 6 patients (13%) had mitral valvular calcification, 9 patients (20%) had aortic valvular calcification, and 6 patients (13%) had calcification of both valves. The patients with VC were older than patients without VC (66±14 vs. 50±18). The patients with aortic calcification had longer HD duration than others (48±29 vs. 27±24 months). Patients with VC had higher systolic and diastolic blood pressures than patients without VC. The patients with mitral calcification had higher C-reactive protein (CRP) levels (14 ± 13 vs. 7 ± 7). No significant differences were found with respect to calcium, phosphorus, parathyroid hormone, alkaline phosphatase and mean Ca × P product. Our study confirmed that there is an increased prevalence of VC in HD patients. Age is a risk factor for cardiac VC in HD patients. Longer HD duration was associated with aortic valve calcification. In addition, elevated level of CRP is associated with mitral valve calcification in HD patients.

4

Relationships Between Perception of Illness, Social Support and Hemodialysis Adequacy

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Sak J. , Dryl-Rydzyńska T. , Książek A.

Polish Journal of Public Health

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2015

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tom 124

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nr 4

174-177

EN

Introduction. The patients in situations of “being ill” have to face not only pain and disabilities, but also problems in their social relationships. Perceptions of illness are results of reactions to the changes in the existential situations, and that these correspond to determined illness coping strategies. Aim. The aim of the research was to determine the relationships between perception of illness and social support, with the indicators of the adequacy of the renal replacement treatment and the level of urea as a biomarker of disease offset. Material and methods. The study was conducted on a group of 150 patients who were on chronic hemodialysis, and who were suffering from end stage renal disease. The patients were treated at on of the several Fresenius Medical centres. As a group, average Kt/V value was 1.45 (SD=0.22) and the URR ratio 71.78 (SD=5.95). Moreover, average urea concentration before HD equaled to 133.78mg% (SD=39.68) and after hemodialysis - 38.22mg% (SD=14.60). The research procedure was based on a questionnaire study. This applied three standardized scales: the Imagination and Perception of Illness Scale (IPIS), the brief Illness Perception Questionnaire (IPQ-Brief) and the Berlin Social Support Scale (BSSS). Results. Patients who exhibited higher values of urea concentration in the blood serum measured before HD, perceived their disease (IPIS scale) as causing more motivation loss to carrying out specific activities, as well as mental and physical sphere destruction, pessimism and lost control over the disease. What is more, higher values of urea reduction ratio (URR) positively correlate with the loss of control over the disease (r=-0.20, p=0.024). Moreover, patients characterized by higher values of urea concentration in the blood serum before hemodialysis, evinced greater need for social support (BSSS). Conclusions. The need for social support among ESRD patients treated by hemodialysis does not correlate with dialysis adequacy indicators. Furthermore, the level of urea marked before hemodialysis exhibits an interdependence with psychological determinants of illness perception and social support.

5

Quality of life and functional status in patients with end-stage renal disease

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Strugała M. , Talarska D. , Niewiadomski T. , Dziechciaż M. , Wojewoda K.

Long-Term Care Nursing

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2020

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tom 5

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nr 2

105-118

EN

Aim The specifics of progressive course of the disease leads to the development of functional dependence which contributes to later disability, significantly influences quality of life. The goal of the research described here was to determine the relationship between the functioning of patients treated with hemodialysis and selected socio-demographic factors and quality of life. Material and methods The research included 100 patients in the range 20-90 years of age who were being treated with hemodialysis in a renal replacement facility in the area of western Poland. The average age for the entire group was 59.5±14.4 years of age. The average time spent on dialysis for the group was 44.7 ± 48.6 months. In order to evaluate patients’ functional status the Barthel Index, Lawton’s IADL and the Karnofsky Performance Status Scale were used. In order to evaluate QOL, the multidimensional instrument – the Health Questionnaire Specific for ESRD was used. Results Using the Spearman coefficient correlation moderate and strong correlations were found between particular sub-scales Health Questionnaire Specific for ESRD and functional capacity. There was no statistically significant dependence between the length of renal-replacement therapy and particular scales on the Parfrey et al Health Questionnaire as well as the functional capacity of patients. Conclusions Demographic variables, especially sex and age, and to a lesser degree educational level and marital status have an influence on the results of the Health Questionnaire Specific for ESRD. Activity levels had a signficant influence on the results in the area of QOL

6

SARS-CoV-2 infection in vaccinated maintenance hemodialysis patients despite anti-spike seroconversion: a report of 3 breakthrough cases

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Biedunkiewicz B. , Tylicki L. , Puchalska-Reglińska E. , Dąbrowska M. , Ślizień W. , Kubanek A. , Rąbalski Ł. , Kosiński M. , Grzybek M. , Renke M. , Dębska-Ślizień A.

European Journal of Translational and Clinical Medicine

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2022

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tom 5

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nr 1

12-16

EN

Chronically hemodialyzed (HD) patients are at a high risk of developing very severe forms of COVID-19 disease. In this article we describe three HD patients (all males, aged 70, 70 and 74 years) vaccinated intramuscularly with a two-dose mRNA BNT162b2 vaccine; BionTech/Pfizer Comirnaty, in whom subsequent breakthrough SARS-CoV-2 infections developed. All patients achieved post-vaccine seroconversion for anti-spike antibodies with IgG titers of 445, 227 and 92.5 AU/mL (cut-off, 13 AU/mL) case 1, 2 and 3 respectively. SARS-CoV-2 infection was diagnosed 44, 28 and 48 days after the second dose of BNT162b2 and confirmed with the polymerase-chain-reaction (PCR) test. Two asymptomatic patients underwent this test because of their direct contact with a person with confirmed COVID-19. The third patient reported only a non-significant drop in oxygen saturation, and was hospitalized (case 3). All these patients were characterized by a low post-vaccination neutralizing antibody titer and a high production of these antibodies after falling ill (795, 845 and 5770). Perhaps this production of antibodies is responsible for the mild course of the disease, and the likely reduction of mortality. These breakthrough cases in no way undermine the importance of the vaccinations, and on the contrary argue for their urgency.

7

Survival of tunneled hemodialysis catheters after percutaneous placement

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Weber E. , Liberek T. , Wołyniec W. , Gruszecki M. , Rutkowski B.

Acta Biochimica Polonica

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2016

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tom 63

|

nr 1

139-143

EN

Background. Tunneled catheters are becoming increasingly used as a permanent dialysis access. Easy way of insertion and good long-term patency make them competitive to fistulas in some groups of patients. Methods. Late complications and survival of 180 tunneled catheters inserted from June 2010 to December 2013 in 171 unselected hemodialysis patients were analyzed. Results. The cumulative time of observation was 2103.5 patient-months and median observation was 9 months (range of 0.5-45 months). Only 19 out of 180 catheters were removed due to complications (12 for infections, 4 due to malfunction and 3 because of mechanical damage). Majority of catheters were removed electively: 27 after maturation of arterio-venous fistula (AVF), 4 after kidney transplant, 5 after transfer to peritoneal dialysis and 3 due to the recovery of renal function. At the end of the observation, 58 catheters were still in use and 64 patients had died with functioning catheter. When censored for elective catheter removal and patient death, 88.2% of catheters survived for 1 year. Catheter survival was significantly better in older patients (over 65 years, in comparison to patients < 65 years, p = 0.046). Conclusions. Nearly 90% of all inserted catheters gave reliable dialysis access as long as it was needed. Among them, over 30% of the inserted catheters were in use at the end of the observation period, and over 30% of patients had died with a functioning catheter. The results of tunneled catheters survival are encouraging and they should be taken into consideration during decision-making on vascular access, especially in the older patients.

8

Blood platelets apoptosis in hemodialyzed patients

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Sobol A. , Kamińska M. , Walczyńska M. , Stasiak M. , Szymański J. , Walkowiak M. , Walkowiak B.

Engineering of Biomaterials

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2009

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tom Vol. 12, no. 89-91

29--30

EN

Blood platelet proteome of hemodialyzed uremic patients exhibits significant difference in comparison to the blood platelet proteome of healthy subjects. This alteration is manifested by the presence of high concentrations of low molecular peptides within the whole range of pI. Increased platelet apoptosis has been put forward as a possible cause of this phenomenon (1). The aim of the present research was to assess whether blood platelet populations from hemodialyzed uremic patients exhibit more binding sites for Annexin V (a marker of apoptosis) than control samples from healthy donors. Blood was obtained from uremic patients immediately before and after hemodialysis. At the same time samples from control healthy donors were also collected. Blood was anticoagulated with sodium citrate and was immediately exposed to propidium iodide, fluorescent labeled Annexin V and CD61 antibodies. The samples were incubated for 10 minutes in the dark and next the labeled samples were processed in a BectonDickinson FACScan flow cytofluorymeter. Our preliminary study was performed for 12 hemodialyzed patients, 13nondialyzed uremic patientsand 12 controls. It was found that the blood platelet population of hemodialyzed patients exhibited significantly higher level of fluorescence intensity attributed to Annexin V. Furthermore, this intensity was comparable before and after hemodialysis and was independent on patient age. The results support the hypothesis that blood platelet contact with artificial surfaces during the process of hemodialysys may be partially responsible for triggering blood platelet apoptosis.

9

Assessment and management of pain in hemodialysis patients: A pilot study

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Kafkia T. , Vehviläinen-Julkunen K. , Sapountzi-Krepia D.

Progress in Health Sciences

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2014

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tom 4

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nr 1

53-60

XX

Purpose: To assess pain levels of hemodialysis (HD) patients and to report pain management techniques. Materials and methods: A quantitative descriptive study design with a summative approach to qualitative analysis was held, with a personal interview of the HD patients in a Southern European city hospital (n=70), using the Visual Analog Scales (VAS), the Wong-Baker Pain Scales (WBPS) and McGill Pain Questionnaire. People confused or in a coma, with hearing or reading problems and inability to communicate in the spoken language were excluded. Results: Renal patients under investigation were 69.72 ±12.45 years old, male (58.5%) and on HD for 35.5 ± 27.4 months. In the Wong Baker Scale, pain was rated as “hurts little more” 30.8%, (n=20) and in the VAS 30.8% (n=20) reported 6/10 the amount of pain experienced. Forty-six percent pinpointed internal pain in the legs. Pain experienced was characterized as sickening (70.8%), tiring (67.7%), burning (66.2%), rhythmic (86.2%), periodic (66.2%) and continuous (61.5%). The patients studied mainly manage pain either with warm towel/cloth (85.2% females and all male patients), with massage (84.2% and 88.9%, respectively) or painkillers (47.4% and 52.6%, respectively). In a correlation of gender and pain management techniques, statistical significance was found only with warm towel (p=0.038). Conclusions: As renal patients are an increasing group of healthcare service users, and pain is affecting their everyday life, it is essential to individualize pain evaluation and to provide further education to clinical nurses so that they can effectively manage pain.

10

Plasma levels of catecholamines and asymmetric dimethylarginine levels as predictive values of mortality among hemodialysis patients

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Dziedzic M. , Orlowska E. , Gawel K. , Zawadzka M. , Bednarek-Skublewska A. , Solski J.

Current Issues in Pharmacy and Medical Sciences

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2014

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tom 27

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nr 1

37-40

EN

The aim of the study was to assess plasma concentration of catecholamines and asymmetric dimethyl arginine levels and a possible relationship to predict the mortality rates among hemodialysis patients. The study population comprised 27 subjects, aged 65-70 years. Each patient underwent dialysis thrice a week. Furthermore, the median duration of hemodialysis was 3.5 years. Based on the conducted research, it can be concluded that the concentrations of adrenaline and the level of asymmetric dimethylarginine have predictive value of mortality among hemodialysis patients. Of note, lowering plasma asymmetric dimethylarginine concentration may represent therapeutic target for prevention of progressive renal damage.

11

The effect of perceived social support on the quality of life of hemodialysis patients. A preliminary study.

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Theofilou P. , Stefanidou M. , Giannakopoulou N. , Tzavella F. , Zyga S. , Tsironi M. , Alikari V.

Progress in Health Sciences

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2020

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tom 10(1)

19-25

EN

Purpose: Recent studies have shown that the role of social support is a predictive factor influencing the course of the disease. The current study is focused on patients’ assessment of quality of life and the relationship of the latter with perceived social support. Materials and methods: A total sample of 40 hemodialysis patients voluntarily participated in this study. Participants were recruited from two clinics in Athens and have been under hemodialysis. The measures used were the Missoula- Vitas Quality of Life Index–15 and the Multidimensional Scale of Perceived Social Support. For the data analysis descriptive statistics, parametric Pearson r test and Non-parametric Spearman’s rho test were used. Statistical level was set up at 0.05. Results: The results of the current study provide good quality of life of hemodialysis patients and significant statistical significance between quality of life in several domains. Conclusions: This study concludes that the participants’ assessment of quality of life is poor regarding the well-being dimension. Also, perceived social support is significantly related to quality of life

12

Adsorption of fibrinogen and albumin in a cellulose membrane for hemodialysis

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De Reytere H. A. , Boonaert C. J. P. , Rouxhet P. G. , Dewez J.-L.

Inżynieria Biomateriałów

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2001

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tom R. 4, nr 17-19

14-14

13

Bilateral brachiocephalic vein stenosis in a chronic hemodialysis patient with well-functioning arteriovenous fistula – A rare entity

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SINGH M. G. , KUMAR V.

Polish Journal of Surgery

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2021

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tom 93

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nr 4

74-75

EN

Introduction: Central vein stenosis has been reported in patients of end stage renal disease with subclavian vein being more commonly affected than brachiocephalic vein. Case report: We present a case of young female with bilateral brachiocephalic vein obstruction following arteriovenous fistula creation for hemodialysis.

14

Comparison of results of placement of cuffed –tunneled hemodialysis catheter in internal jugular vein with subclavian vein for long -term dialysis

100%

Zafarghandi M.-R. , Nazari I. , Taghavi M. , Salimi J. , Moini M. , Askarpour S.

Polish Journal of Surgery

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2013

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tom 85

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nr 3

133-136

EN

Aim of the study was to comparison between internal jugular vs. subclavian vein cuffed tunnel catheter placement for dialysis. Material and methods. Cases who required central venous catheter for dialysis were included in this study. Forty cases were included in this study and divided to two groups. Catheters were placed randomly in internal jugular vein or subclavian. Patients were followed for 6 months. Early and late complications of catheter’s placement were recorded. Analysis was done using Spss ver 13.0 (Chicago, IL, USA). Results. There were no significant differences between subclavian and internal jugular vein regarding occurrence of infection resulted in extraction or treatment. Also there were no significant differences regarding occurrence of thrombosis resulted in extraction or treatment. Failure rate was significantly higher in cases with internal jugular vein catheter compared to cases with subclavian vein catheter (p=0.04). Conclusion. Failure rate was significantly higher in cases with internal jugular vein catheter compared to subclavian cathether. Subclavian catheter is more appropriate route for catheter placement.

15

QUALITY OF LIFE AND ITS GENERATING FACTORS IN HEMODIALYSIS PATIENTS HOSPITALIZED AT THE REGIONAL HOSPITAL IDRISSI KÉNITRA MOROCCO

88%

Touil D. , Boualam A. , El Harchaoui I. , Louragli I. , Aouane M. , Touhami Ahami A. O.

Acta Neuropsychologica

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2022

|

tom 20(1)

67-79

EN

To assess the quality of life of patients with chronic end-stage renal failure under hemodialysis, and to determine its main generators in hemodialysis patients. This is a descriptive and analytical cross-sectional study carried out at the regional hospital of Kénitra (Morocco) in the level of the hemodialysis unit during a period of 3 months with 70 hemodialysis patients diagnosed and treated for chronic renal failure. Data were collected using a questionnaire comprising the socio-demographic, clinical, and nutritional characteristics of Hemodialysis patients and a KDQOL scale (Kidney Disease Quality Of Life) that assesses the quality of life. The scores of the KDQOL-36 were used to assess family, social support, and social support from caregivers. The average age was 51.66± 15.96 years with 57.1% of patients who are female. The components of the quality of life studied show an alteration in the quality of life with a decrease in the scores of the “component of physical health” dimensions with a score of 27.64 ± 29.13,“Component of mental health” with a score of 37.81 ± 22.99, “effects of kidney disease on daily life” with a score of 48.41 ± 21.22 and “burdens of kidney disease” with a score of 28.47 ± 21.50. While the dimension “Symptoms / problems of kidney disease” remains close to normal with a score of 64.61 ± 17.98. Our results showed that certain dimensions of the quality of life correlate with age, sex, family situation, level of education, the presence of a transplant plan, the presence of comorbidities and the duration of hemodialysis. Our study also found a correlation between family social support and quality of life in its “Burdens of Kidney Disease”, “Effects of Kidney Disease on Daily Living”, and the overall quality of life score. On the other hand, there is no significant relationship with support from caregivers. The quality of life of hemodialysis patients is deteriorating. It is influenced by several parameters including family and caregiver social support. The involvement of the family and the health care team in the psychological support process is paramount.

16

Estimation of Predictive Factors Affecting Patency of Dialysis Arteriovenous Fistulae

88%

Mularczyk T. , Kostewicz W.

Polish Journal of Surgery

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2010

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tom 82

|

nr 3

147-158

EN

Native arteriovenous fistula is considered the best type of access for dialysis. Its function is affected by multiple factors.The aim of the study was to identify risk factors of the loss of fistula patency.Material and methods. Between 1990-2004, 218 patients underwent 276 surgical procedures involving vascular access creation. In 245 (89%) of cases, a fistula was created using only patient's own blood vessels; in 31 (11%) of cases a vascular graft was implanted. 158 (64%) radio-cephalic fistulae were created, 15 (6%) radiobasilic fistulae, 33 (14%) brachiocephalic and 39 (16%) brachiobasilic fistulae. Duration of primary patency was identified for 217 native fistulae. Age, gender, diabetes mellitus, type, mode of creation and fistula location, vein translocation, type of anastomosis and time of initial cannulation were analyzed as potential factors affecting the fistula patency. Cox proportional hazards model was used in the analysis.Results. Probability of fistula patency loss in patients above 46 years of age was 2.12-fold higher than in younger patients and 1.62-fold higher for end-to-side anastomosis versus end-to-end anastomosis. Risk of loss of patency in fistulae cannulated for the first time within the first 14 days, 15-21 days and 22-35 days from their creation was 31-, 19- and 7-fold higher than when they were cannulated after the first 35 days.Conclusions. Type of vascular anastomosis, age above 46 years and time of the first cannulation are independent risk factors of the loss of patency of vascular access. First cannulation should not take place earlier than 7 weeks after its creation.

17

Using proton-pump inhibitors among hemodialysis patients - single academic dialysis center’s preliminary experience

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Rakowska M. , Brzósko S. , Dąbrowska E. , Jabłońska E. , Szczykowska J. , Prusator P. , Kwaśniewska A. , Naumnik B.

Progress in Health Sciences

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2017

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tom 7(1)

39-43

EN

Introduction: Proton-pump inhibitors (PPIs) are a class of drugs which decrease gastric acid production, their overuse is becoming increasingly common. Purpose: The aim of this study was to evaluate medical indications for PPIs in a cohort of prevalent hemodialysis (HD) patients and their awareness about the medical effects of these drugs. Materials and methods: The study was performed in 78 HD patients enrolled in a chronic dialysis program in a single academic dialysis unit. The study was based on medical history obtained from the patients (survey about drugs they take with intention of revealing PPIs, indications for the treatment, their awareness of the mechanism of action of these drugs).Results: 46 patients (59%) took or have been taking PPIs. Almost half (49%; n=22) had no clear medical indications for the drugs. Prescription of PPIs without medical indications was more common among nephrologists (27%), when compared with gastroenterologists (5%; p<0.05). Only 29% (n=13) of patients taking PPIs were aware of the mechanism of action of the drugs. Conclusions: Results of this study reveal the problem of PPI overuse among HD patients. Gastroenterologists usually prescribed PPIs according to medical indications. Lack of patients’ knowledge about the indications for PPI therapy is overwhelming.

18

Selenium supplementation to chronic kidney disease patients on hemodialysis does not induce the synthesis of plasma glutathione peroxidase

88%

Zachara B. A. , Gromadzinska J. , Zbrog Z. , Swiech R. , Wasowicz W. , Twardowska E. , Jablonska E. , Sobala W.

Acta Biochimica Polonica

|

2009

|

tom 56

|

nr 1

183-187

EN

Background: Numerous authors have shown that selenium (Se) concentration and glutathione peroxidase (GSH-Px) activity in plasma of chronic kidney disease (CKD) patients are lower than in healthy subjects, but there are only few publications on the level of GSH-Px protein in those patients and no reports on the effect of Se supplementation to HD patients on the level of this enzyme. Subjects and Methods: Se concentration and GSH-Px protein level in plasma were measured in a group of 30 CKD patients on hemodialysis (HD) supplemented with 200 µg Se/day for 3 months, and 28 patients on HD administered with placebo. Se concentration was measured by graphite furnace atomic absorption spectrometry and plasma GSH-Px protein level by the sandwich ELISA method using polyclonal antibody specific for human plasma GSH-Px. Results: Se concentration in patients on placebo did not change throughout the 3-month study period, but increased significantly in Se supplemented group. Se supplementation to CKD patients on HD had no effect on the level of GSH-Px protein. Conclusions: The lack of GSH-Px protein in CKD patients on HD is not linked to Se deficiency since the level of this element increased after Se supplementation while enzyme protein level did not change. The damaged kidney of HD patients is unable to synthesize GSH-Px, even after induction with selenium.

19

Influence of haemodialysis on magnesium metabolism in patient with chronic renal failure

88%

Walasek L. , Rzeszotarski J. , Marszalek A.

Journal of Elementology

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2005

|

tom 10

|

nr 4 Suppl.1

107-108

20

Venous aneurysm complicating arteriovenous fistula access and matrix metalloproteinases

75%

Serra R. , Butrico L. , Grande R. , Placida G. D. , Rubino P. , Settimio U. F. , Quarto G. , Amato M. , Furino E. , Compagna R. , Amato B. , Gallelli L. , Franciscis S. d.

Open Medicine

|

2014

|

tom 10

|

nr 1

EN

Introduction: An arteriovenous fistula (AVF) for placed for hemodialysis may be burdened by one particular complication-the formation of a venous aneurysm. It has been shown that matrix metalloproteinases (MMPs) and neutrophil gelatinase-associated lipocalin (NGAL) could represent markers of disease in both venous and arterial vessels. Materials and methods: This case study reports a rare case of enormous venous aneurysm-correlated MMP and NGAL levels in a woman with an AVF. Results: Significantly higher levels of plasma MMP-1, MMP-8, MMP-9, and NGAL were detected in this patient during aneurysmal evaluation before the surgery; these levels significantly decreased 1, 3 and 6 months after surgery. Conclusion: MMP and NGAL levels could represent a marker of aneurysmal disease, and their plasma evaluation could help physicians to stratify the risk of complications in patients with an AVF.