Wyniki wyszukiwania - Biblioteka Nauki

1

Comparison of SVM and K-NN Classifiers in the Estimation of the State of the Arteriovenous Fistula Problem

100%

Grochowina M. , Leniowska L.

Annals of Computer Science and Information Systems

|

2015

|

tom 5

241-246

EN

The paper presents a concise report on the comparison of the classifiers k-NN and SVM in the case of a fuzzy classification of the arterio-venous fistula based on audio recordings. What has been used in the studies are the acoustic signals taken from both healthy patients as well as those diagnosed with the narrowing of a fistula in a mild and major degree of stenosis. In the publication there have been selected two features, each presenting one- time and frequency domain, which enable a quite clear depiction of the classification result. The aim of the study is to develop a solution enabling the detection of fistula's pathologies at an early stage.(original abstract)

2

Clinical and Economic Analysis of Non-Medical Technologies in Russia

80%

Holownia M. , Vorobiev P. , Krasnova L. , Bezmelnitsina L.

Journal of Health Policy and Outcomes Research

|

2013

|

nr nr 2

58-69

EN

Health technology assessment includes several aspects: (1) technology position in health care system (characteristic of disease burden and expected socio-economic impact of technology), (2) the main characteristics of studied technologies, (3) clinical efficacy (experimental and in typical clinical practice), (4) safety, (5) clinical and economic evaluation, (6) the ethical aspects of technology applications, (7) psychological aspects, (8) legal aspects, (9) organizational and logistic issues, (10) social issues, including equitable distribution of resources and fair access to technology. Any assessment of medical technology expects answers to be provided to all the above questions. Non-drug medical technologies can be divided on the basis of different classification approaches. From the position of the functional approach - there are diagnostic, therapeutic (invasive, non invasive), rehabilitation, prevention, and technologies for care and maintenance functions. Regarding the use of different components, there are technologies which include drugs or blood components, also foodstuffs for special nutritional uses or medical devices. An example of medical devices may be laboratory gear used for in vitro studies. The paper presents evaluation results of technologies, which employ medical devices. Finally, there are institutional medical technologies. In this article, the authors present studies about therapeutic, prophylactic and organizational technologies. Prevention of contact dermatitis and ulcers in immobilized patients with urinary incontinence. Clinical and economic research unit for physiotherapy and an assessment of the organization of medical technologies that was conducted, due to reforms in the Russian health care system.(original abstract)

3

The German AMNOG and its Current Potential Implications on the Spanish and Belgian Pricing and Reimbursement Decisions

80%

Walzer S. , Annemanns L. , Parow D. , ZoellneZoellner r Y. , Shekarriz S. , Antonanzas F.

Journal of Health Policy and Outcomes Research

|

2013

|

nr nr 1

64-71

EN

Background: EU policymakers have implemented mechanisms to slow down the rate of increase in health care costs. The most recent reform that came into effect in Germany was the Act to Reorganise the Pharmaceutical Market (AMNOG - Das Arzneimittelmarktneuordnungsgesetz (). Methods: Exemplarily for countries, which used Germany as a price reference country, Spain and Belgium were chosen for pilot evaluation if AMNOG might have any further impact on reimbursement and pricing decisions in these countries. The general market access and potential impacts on clinical development programs will be discussed and evaluated. Results: In Spain, GBA assessments may influence the central decisions in pricing and reimbursement in the sense that lower prices will be expected for new drugs in the benchmarking process. In Belgium, AMNOG will also have an impact: the Price Commission will possibly observe lower prices than before, what may lead to other decisions for approved Belgian prices. More importantly, the decisions in Germany, related to added benefits of new drugs, might influence the Commission members. Finally, clinical developments of new compounds may also be influenced by AMNOG, regarding the requests of reimbursement decision makers for special clinical trial designs. Conclusions: The potential impact on additional clinical benefits and price decisions with the Spitzenverband der Krankenkassen may be observed in some other countries as well. Furthermore, the impact on future clinical development programs of new compounds might as well be significant. Further research and experience in Germany and other countries is needed and awaited. (original abstract)

4

Development of a Novel Technology for Rapidly Rotating Systems for Medical Technology

80%

Klaeger U. , Schmucker U. , Galazky V.

Management and Production Engineering Review

|

2013

|

tom 4

|

nr nr 4

28-34

EN

Rapidly rotating systems such as centrifuges are widely used in medicine and laboratories to eﬃciently separate different constituents of liquids. Rotors, which hold sample containers, are an essential part of centrifuges. Since they are subjected to extreme mechanical loads, rotors are one of a centrifuge's core safety components. Their deficits served as the point of departure for the development of a novel manufacturing technology, which is based on carbon fiber-reinforced polymers (CFRP). Its supporting structure is entirely in the loading plane, thus enabling the rotor to absorb higher centrifugal forces while requiring the same amount of material. The new design concept for the load-bearing structure includes a geodesically molded annular support member. It transmits forces better than present products and increases rigidity. In order to eliminate the known problems with obtaining the necessary manufacturing quality of hollow fiber composite bodies, the authors developed the process of centrifugal infusion. Their proposed solution is based on generating higher gravitation forces, thus effectively eliminating detrimental gas pockets and simultaneously optimizing surface quality and impregnation. (original abstract)

5

Approach to Uncertainty in Health Technology Assessment in a Central and Eastern European Country: Appraisal of Cancer Drugs by a Polish HTA agency in presence of high Crossover Rates in Clinical Trials.

80%

Panasiuk A. , Homa M. , Pawlik D. , Prząda-Machno P. , Kaczor M.

Journal of Health Policy and Outcomes Research

|

2016

|

nr nr 2

17-34

EN

Background: Health technology assessment (HTA) plays an important role in reimbursement decision making in Poland and its principles are similar to those used in other countries. However, specific inter-country differences, such as substantial divergence in budgetary resources, may lead to variation in actual HTA practices, e.g. in the approach to uncertainty. Cancer drug reimbursement is a decision-taking area associated with substantial uncertainty. One of its important sources is the presence of crossover (treatment switching) in clinical trials. Objectives: To review the appraisal processes completed for cancer drugs by the Polish HTA agency (AOTMiT) and to compare AOTMiT to the British, Australian and Canadian HTA bodies with respect to strategies of addressing crossover-related uncertainty. Methods: Cancer drug assessment processes in AOTMiT, where a substantial crossover took place were reviewed and subsequently matched with the assessments conducted by NICE, PBAC and pCODR. Ways to approach the crossover-related uncertainty, the influence of uncertainty on the recommendation and uncertainty management strategies were examined. Results: 29 HTA processes related to 6 drugs were included. The crossover rate ranged from 51% to 85% and ITT analyses did not show statistically significant survival benefit. AOTMiT more often yielded negative recommendation, showed less consistent approach to crossover-related uncertainty and a narrower scope of adopted uncertainty management strategies. Conclusions: Crossover constitutes a vital source of uncertainty in the assessments of new cancer therapies. The lack of consistent standards decreases the transparency of assessment processes and can contribute to undertaking suboptimal reimbursement decisions.(original abstract)

6

Utilization of Single Whole Body Vibration Training Unit in Rehabilitation of Elderly Patients with Neurological Disorders

80%

Majerník J. , Dziaková M. , Živčák J.

Annals of Computer Science and Information Systems

|

2015

|

tom 5

275-279

EN

-Whole body vibration (WBV) techniques are increasingly applied in rehabilitation processes to improve patients' functional mobility. Therapeutic usage of WBV reported enhanced muscular strength, power or even bone density. Therefore, the purpose of our study was to investigate immediate response of single WBV training unit on mobility of elderly patients with neurological disorders. Nineteen patients (66.74 ± 3.65 years, 6 males and 13 females) were assessed before WBV (10 min, 30 Hz, vertical 2 mm) and then 1 min afterwards. Individual changes in gait kinematics indicated positive effects of WBV, while kinematics of the gait was more symmetric considering right and left side. Individually, depending on the disease's severity, these changes were more or less significant. The improvements in gait kinematics convinced us that WBV can be carefully used in patients' therapy and it may be used together with individually planed rehabilitation processes to bring more satisfying results. (original abstract)

7

Detection of Breast Abnormalities of Thermograms based on a New Segmentation Method

80%

Ali M. A. S. , Sayed G. I. , Gaber T. , Hassanien A. E. , Snasel V. , Silva L. F.

Annals of Computer Science and Information Systems

|

2015

|

tom 5

255-261

EN

Breast cancer is one from various diseases that has got great attention in the last decades. This due to the number of women who died because of this disease. Segmentation is always an important step in developing a CAD system. This paper proposed an automatic segmentation method for the Region of Interest (ROI) from breast thermograms. This method is based on the data acquisition protocol parameter (the distance from the patient to the camera) and the image statistics of DMR-IR database. To evaluated the results of this method, an approach for the detection of breast abnormalities of thermograms was also proposed. Statistical and texture features from the segmented ROI were extracted and the SVM with its kernel function was used to detect the normal and abnormal breasts based on these features. The experimental results, using the benchmark database, DMR-IR, shown that the classification accuracy reached (100%). Also, using the measurements of the recall and the precision, the classification results reached 100%. This means that the proposed segmentation method is a promising technique for extracting the ROI of breast thermograms.(original abstract)

8

Materiały porowate do zastosowań medycznych

60%

Szczepkowska M. , Łuczuk M.

Systems Supporting Production Engineering

|

2014

|

nr 2(8) Inżynieria Systemów Technicznych

231-239

XX

W artykule poruszono zagadnienia związane z zastosowaniem materiałów porowatych w medycynie wraz technologią ich wytwarzania oraz właściwościami. Zaprezentowano przegląd literaturowy dotyczący materiałów ceramicznych oraz metalicznych, a także część wyników własnych badań naukowych porowatych stopów z pamięcią kształtu. (abstrakt oryginalny)

EN

The paper addresses the issues associated with the application of porous materials in medicine, properties and technology for their preparation. The review of literature of ceramic and metallic materials and also some results of my own research porous shape memory alloys has been presented. (original abstract)

9

Comparing the Crisp and Fuzzy Approaches to Modelling Preferences Towards Health States

60%

Kamiński B. , Jakubczyk M.

Multiple Criteria Decision Making / University of Economics in Katowice

|

2017

|

tom 12

75-89

EN

Understanding societal preferences towards health is vital in public decisions on financing health technologies. Thought experiments in which respondents choose between health states are used to understand the importance of individual criteria. Competing models of preference structure can be compared by their ability to explain empirical observations. One of the key challenges when constructing such models is that they have to aggregate preferences defined in multiple-criteria space. In the present paper, we test whether treating the impact of health worsening (defined using EQ-5D-5L descriptive system, i.e. decomposing health status in five criteria) as a fuzzy concept can improve the model fit. To test if fuzzy approach to multiple-criteria preferences aggregation is valid, we compare a standard, crisp model (SM) with two models using fuzzy sets (JKL, previously proposed in the literature; and FMN introduced here). We find FMN better than SM, and SM better than JKL. Anxiety/depression and pain/discomfort seem to weigh most in preferences. According to FMN, self-care and usual activities are associated with largest imprecision in preferences. The respondents are susceptible to framing effects when time unit is changed: e.g. measuring the duration in days results in short intervals mattering more than when expressed as weeks. We conclude that the fuzzy-based framework is promising, but requires careful work on the exact specification.(original abstract)

10

Early Medical Technology Assessments of Medical Devices and Tests

60%

Mikudina B. , Redekop K.

Journal of Health Policy and Outcomes Research

|

2013

|

nr nr 1

26-37

EN

Background: Classic medical technology assessment (MTA) is typically conducted at the end of the development process to assess the overall value of a drug, medical device or diagnostic test. Recently, researchers and manufacturers have recognized that MTA in the early phases could help to make better decisions about further development, the regulatory and reimbursement strategy, and allocating public support for new technologies. The aim of this study is to introduce the most commonly used methods in early MTAs of emerging technologies and examine which methods have been used in the early MTAs of medical devices and tests. Methods: An explorative literature review. Results: Classic MTA supports particularly regulators and payers in market and reimbursement decisions, while early MTA primarily supports decisions of manufacturers about investments and strategies regarding further development as well as decisions by policymakers about public support. Important methods that can be used in early MTAs of medical devices include early health economic modelling, the headroom method, the Bayesian analytical framework, clinical trial simulation, multi-criteria decision analysis and value of information analysis. Only a few articles have been described early HTAs of devices and tests and most of these have used economic modelling, sometimes in combination with other methods. Conclusions: Various methods can be applied in performing early MTA. While early MTA follows the same steps as classic MTA, repeated assessments and sensitivity analysis play a more significant role.(original abstract)

11

Smart Solutions for Improving Working Processes. A Research Experiences from Dental Clinic

60%

Bartnicka J. , Lara J.

Multidisciplinary Aspects of Production Engineering

|

2019

|

tom 2

600-611

EN

Arm Mbed. (2018). Understanding the different types of BLE Beacons,https://os.mbed.com/blog/entry/BLE-Beacons-URIBeacon-AltBeacons-iBeacon/^^Brokaw, S. (2014). The expectation of Quick Response (QR) Codes in print media: An empirical data research anthology. Journal of undergraduate research.^^Davenport ,T.H., Prusak, L. (1998). Working knowledge. Harvard Business School Press, Boston.^^Filos, E. (2006). Smart organizations in the digital age In: Mezgár, I. (ed.) Integration of Information and Communication Technologies in Smart Organizations. Idea Group, Hershey.^^Ghosh, B., Scott, J.E. (2008). Knowledge Management for Healthcare Organizations: Comparing Strategies with Technical Support. Proceedings of the 41st Hawaii International Conference on System Sciences (http://www.ae.isu.edu.tw/upload/83202/12/files/dept_12_lv_3_12612.pdf).^^Jia, X. (2012). RFID technology and its applications in Internet of Things (IoT).^^Kaźmierczak, J., Loska, A., Kucera, M., Abashidze, I. (2018) Technical infrastructure of "smart city": needs of integrating various management tasks. In: MAPE 2018. Conference proceedings. 1,(1), 467-473.^^Liebowitz, J., Wilcox, L.C. (1997). Knowledge management and its integrative elements. CRC Press, Boston.^^Bhuptani, S.M. (2005). Components of RFID systems. Deploying Radio Frequency Identification Systems.^^Newell, S., Robertson, M., Scarbrough, H., Swan, J. (2002). Managing knowledge work. Palgrave, New York.^^Nonaka, I. (1994). A dynamic theory of organizational knowledge creation. Organizational Science 5, 14-37.^^Nonaka, I., Takeuchi, H. (1995). The knowledge-creating company. Oxford University Press, New York.^^O'Leary, D.E. (1998). Knowledge management systems: converting and connection. IEEE Intelligent Systems, May/June, 30-33.^^Polanyi M. (1966) The tacit dimension. Routledge and Kegan Paul, London.^^Preto, S., Gomes, C.C. (2018). Three Times Smart - Smart Workplaces, Smart Lighting &Smart Glass. In: P. Arezes (ed.), Advances in Safety Management and Human Factors, Advances in Intelligent Systems and Computing 604.^^Ruggles, R. (1998) The state of the notion: knowledge management in practice. California Management Review 40, 80-89^^Swan, J., Scarbrough, H., Preston, J. (1999). Knowledge management: The next fad to forget people? 7th European Conference on Information Systems, Copenhagen, Denmark.^^Zhao J., Ordóñez de Pablos, P., Qi, Z. (2012). Enterprise knowledge management model based on China's practice and case study. Computers in Human Behavior 28, 324-330.

12

Ocena nielekowych technologii medycznych

60%

Łanda K.

Problemy Zarządzania

|

2004

|

tom 2

|

nr nr 4 (6) Farmakoekonomika

99-110

XX

Artykuł dotyczy problemów związanych z oceną nielekowych technologii medycznych oraz implementacji raportów i implikacji systemowych w obszarze tych technologii. Dokonując oceny technologii nielekowych, w większości przypadków należy spodziewać się, że odnalezione badania kliniczne będą niższej jakości niż te dotyczące leków. Autor wskazuje również podstawowe ograniczenia „evidence" w obszarze technologii nielekowych oraz przyczyny takiego stanu rzeczy. Zwraca uwagę, że standaryzacja w obszarze rejestracji i finansowania technologii nielekowych jest daleko mniej posunięta. Podaje przykłady raportów HTA (Health Technology Assessment) w omawianym obszarze oraz efekty ich systemowego wykorzystania w Polsce.

EN

The article describes the most important analytical issues related to assessments of non-drug medical technologies as well as implementation of results of HTA reports in Poland and systemic implications in the area of non-drug technologies. Economic evaluation of non-drug technology is usually based on lower quality of clinical trials in comparison to drugs. Considerations refer to basic limitations of evidence in the area and causes of their presence. Standardisation of registration and reimbursement of non-drug technologies is much less developed - the reasons were discussed. Some examples of HTA reports are presented and effects of their use in reimbursement policy in Poland described. (original abstract)

13

Koszty medyczne w farmakoekonomice

60%

Wrona B.

Folia Oeconomica Bochniensia

|

2006

|

nr nr 5

117-124

XX

Opracowanie porusza problem kosztów medycznych w farmakoekonomice. Farmakoekonomika to dziedzina wiedzy ale także doskonałe narzędzie praktyczne. Pozwala się zorientować w jaki sposób należy podchodzić do kosztów i sposobu leczenia, pamiętając równocześnie, że najważniejsze jest nie tylko rachunek ekonomiczny ale zorientowanie na pacjenta i ratowanie życia ludzkiego za wszelką cenę.

EN

This article focuses on issues of costs in pharmacoeconomic. The most important is to safe people’s life and patient orientation, not economic calculus.(KZ)

14

Health Technology Assessment in Reimbursement Policy of the Slovak Republic

60%

Tesar T.

Journal of Health Policy and Outcomes Research

|

2012

|

nr nr 1

21-23

EN

Evidence suggests that availability of medicines on the Slovak market is both comprehensive and prompt. The low co-payment rate of reimbursed products results in easy access to highly priced patented products. There is always at least one treatment available in determined therapeutic classes with no co-payment. Evidence suggests that Slovak pharmaceutical expenditures do not result in the most cost effective outcomes. The use of HTA in the decision-making process is vague.(original abstract)

15

Analizy ekonomiczne w procesie oceny technologii medycznych

60%

Kolasa K.

Master of Business Administration

|

2009

|

tom 17

|

nr nr 3

65-72

XX

Rosnące potrzeby zdrowotne wywierają coraz większą presję na ograniczone budżety systemów ochrony zdrowia na całym świecie. Nieustannie poszukuje się coraz nowych metod racjonalizacji dostępu do świadczeń zdrowotnych. Powołanie Agencji Oceny Technologii Medycznych przyczyniło się do rozpowszechnienia farmakoekonomiki na polskim rynku. Analiza kosztów-efektywności (CEA) oraz wpływu na budżet (BIA) jest uznawana za skuteczne narzędzie farmakoekonomiczne w budowaniu optymalnej alokacji ograniczonych zasobów w sektorze ochrony zdrowia. Coraz częściej podkreśla się potrzebę oceny ekonomicznych konsekwencji wprowadzenia nowych metod leczenia, stąd zagraniczne doświadczenia w tym zakresie wydają się szczególnie cenne. Analiza kosztów-efektywności polega na jednoczesnym porównaniu kosztów i wyników zdrowotnych dwóch alternatywnych terapii. Jej celem jest maksymalizacja korzyści zdrowotnych w ramach dostępnych zasobów finansowych. Analiza wpływu na budżet koncentruje się na badaniu konsekwencji finansowych wprowadzenia nowej metody leczenia i pozwala płatnikowi podejmować decyzje w ramach dostępnych środków finansowych. Podczas gdy analizę kosztów-efektywności prowadzi się głównie z perspektywy społecznej, w drugiej z analiz przyjmuje się perspektywę płatnika. Przyjęcie takiego założenia rodzi wiele konsekwencji i może prowadzić do przeciwstawnych decyzji. (abstrakt oryginalny)

EN

The growing patients' demands exert heavy pressure on health care budgets all over the world. There is a constant search for new methods for the rationalization of health care resources. The foundation of the Health Technology Assessment Agency introduced pharmacoeconomics techniques in the Polish market. Cost Effectiveness Analysis (CEA) and Budget Impact Analysis (BIA) are regarded as an effective tool for the allocation of scarce financial resources. As the need for economic evaluation of health care programs is becoming more and more recognized in Poland, foreign experience in this field seems to be very desirable. CEA is a form of economic evaluation where costs and health effects are estimated simultaneously against other relevant intervention methods. Budget Impact Analysis is a financial tool that helps health care providers estimate the financial consequences of the introduction of new intervention methods. The aim of CEA is the maximization of health gains. The aim is to establish which intervention method is more efficient. On the other hand, BIA focuses on the issues of ffordability and helps decision-makers remain within a certain budget. While CEA is usually carried out from the societal perspective, BIA is always preformed from the budget-holder perspective. This assumption has various implications and may sometimes lead to contradictory decisions. (original abstract)

16

Reimbursement and Value Assessment Frameworks: Ensuring Patients' Access to Asthma Medicines in Ukraine

60%

Zaliska O. , Piniazhko O. , Ilyk R. , Irynchyn H.

Journal of Health Policy and Outcomes Research

|

2017

|

nr nr 1

43-47

EN

Background. Health technology assessment (HTA) introduction and implementation for development of the National List of Essential Medicines (NLEM) took place in Ukraine in 2016 in the context of National Drug Policy until 2025. The study aimed to outline the reimbursement of medicines for asthma treatment, market access for innovative medicines, main steps of HTA development in the decision making process in Ukraine in line with the international requirements and future directions. Methods. Literature review was conducted examining legislation database and scientific publications on the study issues in Ukraine: epidemiology of asthma, reimbursement programs, HTA development, affordability of innovative medicines for asthma treatment, market analysis. The study was performed to investigate the practices, processes and policies of value assessment and their impact in Ukraine. Results. In 2016 a legal framework was developed for the elaboration of NLEM and procedures for reference pricing and reimbursement programs. HTA is used for the inclusion medicines on the list based on the applied evidence of quality, efficacy, effectiveness, safety and economic evaluations adhering to the Order of Ministry of Health (MoH). HTA implementation in 2016 consisted of legislation, HTA training for experts of Expert committee of MoH and development of NLEM. Reimbursement programs for cardiovascular diseases, type 2 diabetes (T2D), asthma have started in April 2017 due to the adopted regulations. Conclusions. HTA use in the decision-making in Ukraine will provide an access to innovative medicines for patients and transparent, consistent decision making process in assessing the health technologies for inclusion on regulatory lists and reimbursement programs.(original abstract)

17

On the Properties of Stochastic Multiple-Criteria Comparison Methods in Health Technology Assessment

60%

Kamiński B. , Jakubczyk M.

Multiple Criteria Decision Making / University of Economics in Katowice

|

2010

|

tom 5

121-133

EN

To ensure the optimal usage of scarce resources in the assessment of health technologies two criteria are used: costs and effectiveness of available options. For each treatment the evaluations of these criteria are obtained from clinical trials, cost and utility studies and therefore are given as random variables. In our research we compare the decision theoretic properties of expected net benefit, cost-effectiveness acceptability curve and expected value of perfect information methods of choosing the optimal treatment.(original abstract)

18

Computer Based Quantification of Normal and Pathological Vocal Folds Phonatory Processes from Laryngovideostroboscopy

60%

Kopczyński B. , Strumiłło P. , Niebudek-Bogusz E.

Annals of Computer Science and Information Systems

|

2015

|

tom 5

269-277

EN

Medical imaging techniques offer novel visualization and analysis methods of the vocal folds during phonation and automatic computation of indices aiding the phoniatrist in a more precise diagnosis of voice disorders. The aim of this study is to apply computer vision algorithms for qualitative and quantitative analysis of vocal folds' vibrations. Videostroboscopic examinations of the larynx were carried out for 30 patients. Image pre-processing and image segmentation algorithms were applied to compute the glottis area during phonation. The glottovibrograms which are spatio-temporal visualizations of the vibrating vocal folds were also built. The proposed indices allow for a quantitative and comparative analysis of normal and disordered phonatory processes. The conducted pilot study has confirmed the validity of the computer aided imaging methods for the qualitative and quantitative analysis of the videostroboscopic images of the phonatory motions of the vocal folds. (original abstract)

19

Degradation of the Polymer Prosthetic Material in Model Body Fluids

51%

Heimowska A. , Brzeska J. , Morawska M. , Górska M.

Towaroznawcze Problemy Jakości

|

2017

|

nr nr 2

45-57

XX

Celem pracy jest oznaczenie podatności polimerowego materiału protetycznego zawierającego poli(metakrylan metylu) na działanie roztworów degradujących. Wymiernym celem pracy jest udowodnienie, jak ważna jest wymiana całkowitych uzupełnień protetycznych podczas leczenia protetycznego, ze względu na degradację materiału, z którego są wykonane. Zakres pracy obejmuje zbadanie podatności materiału protetycznego na działanie płynów symulujących środowisko panujące w jamie ustnej człowieka. Podczas badań zastosowano roztwory: hydrolityczny, utleniający, sztucznej śliny, amylazy. Podatność badanego materiału sprawdzano poprzez zmianę masy i morfologii powierzchni próbek oraz zmianę ich właściwości termicznych. Na podstawie uzyskanych wyników stwierdzono, że polimetakrylan metylu jest podatny na działanie degradacyjne modelowych płynów ustrojowych. (abstrakt oryginalny)

EN

The aim of this work is to determine the susceptibility of a polymer prosthetic material containing poly(methyl methacrylate), to solutions degrading. A measurable aim of this paper is to prove how important it is to exchange total restorations in the prosthetic treatment, due to the degradation of the material from which they are made. The scope of work includes examining the susceptibility of prosthetic material to liquid simulating the environment conditions in the human oral cavity. The hydrolysis, oxidation, artificial saliva and amylase solutions were used during the test. Susceptibility of the test material was checked by changing the weight and surface morphology of samples and changing their thermal properties.The results concluded that poly(methyl methacrylate) is susceptible to degradation in model body fluids. (original abstract)

20

Zasady przeprowadzania strategii wyszukiwania na potrzeby raportów HTA

51%

Pirek K. , Garbaty T. , Owczarek M.

Zdrowie Publiczne i Zarządzanie

|

2019

|

tom 17

|

nr nr 4

230-240

XX

Systematyczne wyszukiwanie informacji i przygotowanie na ich podstawie przeglądu systematycznego literatury jest stałym elementem pracy nad każdym raportem z zakresu oceny technologii medycznych (ang. Health Technology Assessment, HTA) lub medycyny opartej na dowodach (ang. Evidence-Based Medicine, EBM). Źródłem najnowszych i wiarygodnych informacji naukowych są publikacje z recenzowanych czasopism naukowych, których zawartość można wyszukiwać w przeznaczonych do tego celu bazach danych (między innymi Medline, Embase i Cochrane Library). Celem przeprowadzania strategii wyszukiwania jest odnalezienie w bazie danych wszystkich zamieszczonych w niej materiałów dotyczących interesującego nas tematu. W związku z tym przed przystąpieniem do samego przeszukiwania poszczególnych baz danych należy określić, w jaki sposób będziemy te informacje wyszukiwali. W niniejszym artykule zostaną przedstawione zasady przygotowywania oraz wykonywania strategii wyszukiwania i przeglądów systematycznych literatury na potrzeby raportów HTA na przykładzie baz danych PubMed, Embase i Cochrane Library. Należy jednak zwrócić uwagę, iż przedstawione zasady znajdą zastosowanie również w pozostałych bazach danych publikacji naukowych. Omówione zostaną podstawowe kroki i narzędzia konieczne do przygotowania czułych i swoistych strategii wyszukiwania, w tym: przygotowanie schematu PICO (ang. Population, Intervention, Comparison, Outcome), rodzaje wyszukiwania, operatory logiczne i znaki specjalne oraz filtry. Przedstawione zostaną również najczęściej spotykane problemy i możliwości ich rozwiązania. Dodatkowo zamieszczono również propozycje filtrów do zastosowania w poszczególnych bazach danych, pozwalających na wyszukiwanie specyficznych zbiorów danych (między innymi typy publikacji, rodzaje badań, linie leczenia, specyficzne subpopulacje: wiek, rasa, płeć). (fragment tekstu)

EN

Preparation of HTA reports requires access to the latest and most reliable knowledge in the field of health care. Systematic reviews are the basic tools used to obtain it. In order to find the literature necessary for a systematic review, search strategies are performed in databases. With their help it is possible to thoroughly and reliably search the resources of individual databases and find the required information. Properly executed search strategies also reduce the risk of missing valuable publications. During the preparation of the search strategy, one should use the tools and additional functions implemented in individual databases, thanks to which it is possible to strictly control the process and adapt it to your own needs. Performing a search strategy is a basic skill for anyone who prepares HTA reports. (original abstract)