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FDG-PET-CT in the early response evaluation for primary systemic therapy of breast cancer

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Tőkés T. , Torgyík L. , Kulka J. , Borka K. , Szász A. , Tóth A. , Harsányi L. , Lengyel Z. , Györke T. , Dank M.

Open Medicine

2014

tom 9

nr 2

306-312

Primary systemic therapy (PST) is a standard treatment for patients with locally advanced breast cancer. We report one of our patients to demonstrate the optimal use of FDG-PET-CT in the routine clinical workup during PST, especially when clinicians face contradictory clinical and pathological findings, and to show the advantages of this imaging modality in the decision-making process about the initial treatment choice. By reviewing the literature we would also like to confirm that FDG-PET-CT is highly sensitive in the measurement of the early therapeutic response and the prediction of the complete pathological remission, as early as after the first cycle of chemotherapy is administered.