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1
Content available The effect of hydrazine derivatives of 3-formylchromones on angiogenic basic fibroblast growth factor and fibroblast growth factor receptor-1 in human melanoma cell line WM-115
100%
Łazarenkow A. , Michalska M. , Mirowski M. , Słomiak K. , Nawrot-Modranka J.
Acta Biochimica Polonica
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2017
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tom 64
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nr 3
585-590
EN
The hydrazine derivatives of benzopyrones remain an unexplored group of chemical compounds. This preliminary study investigates the influence of A-5, CH-3 and K-2 derivatives at concentrations of 1, 10, 100 nM and 1 μM on selected biochemical factors of a melanoma cell line WM-115, with regard to their potential angiogenic properties. The studied compounds were found to influence cell proliferation, as well as total protein, bFGF and FGFR1 concentration.
2
Basic fibroblast growth factor and its receptors in human embryonic stem cells
100%
Dvorak P. , Hampl A.
Folia Histochemica et Cytobiologica
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2005
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tom 43
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nr 4
3
The influence of chromone based hydrazones on lipid peroxidation and bFGF concentration in the HL-60 cell line
86%
Lazarenkow A. , Michalska M. , Goraca A. , Mirowski M. , Nawrot-Modranka J. , Piechota-Polanczyk A.
Acta Biochimica Polonica
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2013
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tom 60
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nr 2
EN
 Natural and synthetic derivatives of benzo-γ-pyrones (i.e. flavones, chromones, and coumarins) and their synthetic analogues possess a wide range of biological properties in vitro and in vivo. In this paper we investigated the influence of two hydrazone compounds of chromones, 3-{[(2-dimethoxytiophosphoryl)-2-methylhydrazono]-methyl}-chromen-4-one (CH-3) and 2-amino-6-chloro-3-[(2-hydroxyethyl)-hydrazonomethyl]-chromen-4-one (A-12), on lipid peroxidation and bFGF concentration in the HL-60 cells. Both of the studied compounds had a significant influence on bFGF and TBARS in ranges -137.20 ~ 380.26% and -81.66 ~ -28.68%, respectively, in comparison with the control (counted as 0 %).
4
Content available remote A mutein of human basic fibroblast growth factor TGP-580 accelerates colonic ulcer healing by stimulating angiogenesis in the ulcer bed in rats
72%
Satoh H. , Szabo S.
Journal of Physiology and Pharmacology
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2015
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tom 66
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nr 5
5
Content available Effect of local injection with basic fibroblast growth factor (BFGF) and neutralizing antibody to BFGF on gastric ulcer healing, gastric secretion, angiogenesis and gastric blood flow
72%
Ernst H. , Konturek P. C. , Hahn E. G. , Stosiek H. P. , Brzozowski T. , Konturek S. J.
Journal of Physiology and Pharmacology
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2001
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tom 52
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nr 3
6
Influence of IGF-1, TGF-beta1 and bFGF on gene expression in cruciate ligament and dermal fibroblasts
58%
Hyc A. , Zeberkiewicz M. , Osiecka-Iwan A.
Folia Biologica
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2018
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tom 66
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nr 2
7
Influence of cartilage interstitial fluid on gene expression in dermal fibroblasts
58%
Hyc A. , Moskalewski S. , Stankevic D. , Osiecka-Iwan A.
Folia Biologica
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2017
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tom 65
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nr 1
8
How do tumors actively escape from host immunosurveillance?
51%
Wilczynski J. R. , Duechler M.
Archivum Immunologiae et Therapiae Experimentalis
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2010
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tom 58
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nr 6
435-448
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