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1
High levels of bulky DNA adducts in human sperm correlate with impaired fertility
100%
Horak S. , Polanska J. , Widlak P.
Acta Biochimica Polonica
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2003
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tom 50
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nr 1
EN
Progressive decline in fertility and sperm quality has been reported over the last few decades, especially in industrialized nations. It has been proposed that exposure to factors that induce damage in DNA of spermatogenic cells may significantly contribute to impaired fertility. Here, the 32P-postlabelling method was used to analyze the levels of bulky DNA adducts in sperm cells in a group of 179 volunteers, either healthy subjects or patients with an impaired fertility. The levels of DNA adducts were 1.35-fold higher in the infertile group as compared to healthy individuals (P = 0.012). Similarly, a significant negative correlation between the levels of DNA adducts and measures of semen quality (sperm concentration and motility) has been observed (P < 0.001). In addition, the levels of bulky DNA adducts in sperm cells positively corre­lates with amounts of leukocytes in semen, which were significantly higher in semen of infertile subjects.
2
Usability of the hopoosmotic swelling Water-test - a simple method to assess sperm membrane integrity in mouse spermatozoa
100%
Sliwa L.
Folia Biologica
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1993
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tom 41
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nr 1-2
3
The staining pattern of human sperm with Diff Quik: relationship with sperm head morphology and a sperm chromatin structure assay (SCSA)
84%
Moska N. , Murray E. , Wakefield P. , Matson P.
Reproductive Biology
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2011
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tom 11
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nr 1
4
Effect of reactive oxygen species [ROS] on human sperm cells: the role of magnesium and zinc content of seminal plasma
84%
Kiss S. A. , Zavaczki Z. , Szollosi J. , Koloszar S. , Csikkel-Szolnoki A.
Journal of Elementology
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2002
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tom 07
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nr 2
115-122
5
Adverse effects of endocrine disruptors on the foetal testis development: focus on the phthalates
67%
Habert R. , Muczynski V. , Lehraiki A. , Lambrot R. , Lecureuil C. , Levacher C. , Coffigny H. , Pairault C. , Moison D. , Frydmann R. , Rouiller-Fabre V.
Folia Histochemica et Cytobiologica
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2009
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tom 47
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nr 5
6
New insights about the evaluation of human sperm quality: the aromatase example
67%
Galeraud-Denis I. , Travert C. , De Vienne C. , Said L. , Saad A. , Carreau S.
Folia Histochemica et Cytobiologica
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2009
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tom 47
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nr 5
7
X- and Y-chromosome - bearing sperm selection and detection methods. A review
59%
Gawecka-Szczygiel M. , Kurpisz M.
Folia Histochemica et Cytobiologica
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1995
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tom 33
|
nr 4
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