Pd-catalyzed C-C bond forming reactions have attracted huge interest not only among the synthetic organic chemists but researchers of various disciplines for over two decades because a large panorama of value added organic target molecules can be designed employing this synthesis protocol. Richard F. Heck, Ei-ichi Negishi and Akira Suzuki have been awarded the Nobel Prize in Chemistry 2010 for their pioneering works on these palladiumcatalyzed cross-coupling reactions in organic synthesis. More greener and eco-friendly synthetic conditions together with the recyclability of the Pdcatalyst have been continuously hunted over the years. It is essential to know the different steps and mechanism involved in these C-C coupling reactions together with the active Pd-sites present at the catalytic surfaces. In this review we have focused on discussing various protocols involved in the C-C coupling reactions and gradual developments in Pd-grafted functionalized mesoporous materials. Recyclability and sustainability of the catalyst along with their surface modification strategies have been discussed. Catalytic efficiency of these functionalized mesoporous materials largely depends on strong binding of the Pd-sites with the support matrix. Thus, discussion on different types of supports has also been made.