Wyniki wyszukiwania - Biblioteka Nauki

1

Early Results of Open Fasciotomy as a Treatment of Dupuytren's Disease in Elderly Patients

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Jabłecki J. , Kaczmarzyk L. , Domanasiewicz A. , Kaczmarzyk J.

Polish Journal of Surgery

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2007

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tom 79

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nr 12

746-752

EN

The demand for treatment of Dupuytren's disease by a procedure of limited invasiveness and quick recovery is increasing in accordance with aging of the Polish population. Such a demand is fulfilled by different types of fasciotomy (open, percutaneous needle fasciotomy).The aim of the study was to asses the early results of the open fasciotomy in elderly patients.Material and methods. We treated 38 patients (61 fingers) whose mean age was 72 (SD 12) by open fasciotomy; 43 fingers presented stage III Tubiana contracture, 18 stage IV. The pre-operative total passive extension deficit was 123° (78° for stage III group, 111° for stage IV group). All the procedures were performed in outpatient setting. Patients used splint for 5 days, then performed finger - extension exercises and were encouraged to use their hands normally after 1 week.Results. The evaluation of the results was performed 4 weeks post-op. The greatest improvement in both of the groups was noted in MCP joint - 80% and in PIP joint - 48%, this difference is statistically significant. The general improvement ratio was 76%, greater in stage III group - 82% whereas in stage IV group 69%, but this difference was not statistically significant. All of the wounds healed up to 3 weeks, no complications were observed.Conclusion. The open fasciotomy is a recommendable short term treatment in patients of advanced age, suffering from stage III and stage IV of Dupuytren's disease.

2

Boerhaave Syndrome – over 290 years of surgical experiences. Can the disorder recur?

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Rokicki M. , Rokicki W. , Moj M. , Bsoul T. , Rydel M.

Polish Journal of Surgery

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2019

|

tom 91(3)

27-29

EN

Spontaneous perforation of the esophagus (Boerhaave syndrome) is a rare disease that poses a serious surgical challenge. The analysis of literature concerning the Boerhaave syndrome reveled cases of recurrent spontaneous perforation of the esophagus. The incidental nature of this condition calls for more accurate assessment of all such cases. The authors made a detailed evaluation of the data obtained from eight reports of recurrent Boerhaave syndrome. The data is presented as a summary table comparing the clinical course and outcomes of patients with the primary Boerhaave syndrome as well as recurrent Boerhaave syndrome.

3

Is there any role left for conservative treatment of ameloblastoma?

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Bittar R. F. , Neutzling Lehn C.

Polski Przegląd Otorynolaryngologiczny

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2016

|

tom 5(1)

36-40

EN

Objectives: Ameloblastoma is an aggressive benign tumor of epithelial origin that may arise from the enamel organ, remnants of the dental lamina, the lining of an odontogenic cyst, or possibly from basal epithelial cells of the oral mucosa. It occurs both in maxilla and mandible and may cause important facial deformities. Treat-ment involves radical surgery with a safety margin. The main objective of this paper was to review the most sig-nificant case series in the literature to define which kind of treatment achieves best results, regarding disease control and recurrence rates. Methods: We conducted an analytic literature review of the following databases: Medline and Scielo. Discussion: Treatment with curettage is inadequate and may leave islands of the tumor within the bone. Marginal or en bloc resection is the widest form of therapy with many surgeons advocating margins of excision to include 1.5 cm of clinically normal bone. Conclusion: The high recurrence rates of conservative treatment make it prohibitive.

4

When a constant subsequence implies ultimate periodicity

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Miska P.

Bulletin of the Polish Academy of Sciences. Mathematics

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2019

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tom Vol. 67, no. 1

41--51

EN

We show a curious property of sequences given by the recurrence a0 = h1(0), an = f(n) an-1 + h1 (n) h2 (n)n, n > 0, where f, h1, h2 ϵ Z[X]. Namely, if the sequence (akn+l)n ϵ N is constant for some k ϵ N+ and l ϵ N, then either (a2n+l)n ϵ N = (0)n ϵ N and (a2n)n ϵ N is a geometric progression, or (an)n ϵ N is ultimately periodic with period dividing 2.

5

Lymphovascular space invasion, a prognostic marker for disease recurrence in patients with early endometrioid endometrial cancer

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Hyun Lee S. , Park J.-W. , Han M.

Current Gynecologic Oncology

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2017

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tom 15

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nr 3

183-188

EN

Aim of the study: To evaluate the clinicopathologic factors of early International Federation of Gynecology and Obstetrics (FIGO) stage I–II endometrioid endometrial cancer in a single institution and to emphasize factors contributing to recurrence. Material and methods: We selected several clinicopathologic factors including age, height, body weight, body mass index, cancer antigen-125, FIGO tumor grade, myometrial invasion, lymphovascular space invasion, estrogen receptor/ progesterone receptor status, and adjuvant radiation therapy or systemic chemotherapy. Univariate and multivariate Cox proportional hazard model and Kaplan–Meier estimates were used for analyzing all clinicopathologic factors related to the risk of disease recurrence. Results: The median age was 55.05 years, and the median follow-up time was 35 months. Eleven patients (11%) showed disease recurrence, 3 patients – distant, and 8 patients – local metastasis. In univariate analysis, tumor grade (P = 0.0045) and lymphovascular space invasion (P = 0.0374) were associated with disease recurrence. Multivariate analysis demonstrated an association between any type of recurrence and lymphovascular space invasion (hazard ratio, HR, 6.308; 95% confidence interval, CI 1.851–11.484). Conclusions: Our study showed that the presence of lymphovascular space invasion is an important factor for disease recurrence in early endometrial cancer. Therefore, adjuvant systemic chemotherapy may be considered in patients with early endometrial cancer with lymphovascular space invasion.

PL

Celem pracy była ocena kliniczno-patologicznych cech endometrioidalnego raka błony śluzowej trzonu macicy w stadium I–II według klasyfikacji Międzynarodowej Federacji Ginekologii i Położnictwa (International Federation of Gynecology and Obstetrics, FIGO) w jednym ośrodku oraz podkreślenie czynników wpływających na wznowę choroby. Materiał i metody: W pracy wybrano kilka kliniczno-patologicznych czynników, takich jak wiek, wzrost, masa ciała, wskaźnik masy ciała, wartość antygenu nowotworowego CA-125, stopień w klasyfikacji FIGO, inwazja myometrium, inwazja przestrzeni limfatycznej, status receptorów estrogenowych/progesteronowych, a także radioterapia lub chemioterapia adiuwantowa. W celu oceny wszystkich cech kliniczno-patologicznych związanych z ryzykiem nawrotu choroby zastosowano jednoi wieloczynnikowy model proporcjonalnego ryzyka Coxa oraz analizę metodą Kaplana–Meiera. Wyniki: Mediana wieku wynosiła 55,05 roku, a mediana czasu obserwacji – 35 miesięcy. Nawrót choroby odnotowano u 11 chorych (11%): przerzuty odległe w 3, a wznowę miejscową w 8 przypadkach. W analizie jednoczynnikowej z nawrotem choroby powiązane były stopień złośliwości guza (P = 0,0045) oraz inwazja przestrzeni limfatycznej (P = 0,0374). Analiza wieloczynnikowa wykazała związek między każdym rodzajem nawrotu a inwazją przestrzeni limfatycznej (współczynnik ryzyka – hazard ratio, HR, 6,308; 95% przedział ufności CI 1,851–11,484). Wnioski: Wyniki niniejszego badania wskazują, że obecność inwazji przestrzeni limfatycznej jest ważnym czynnikiem nawrotu wczesnego raka endometrium. Można zatem rozważyć zastosowanie adiuwantowej chemioterapii u chorych na raka endometrium we wczesnym stopniu zaawansowania z inwazją przestrzeni limfatycznej.

6

Mycophenolate mofetil for treatment of idiopathic nephrotic syndrome – a single center experience (preliminary study)

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Tomczyk D. , Jander A. , Mihailescu J. , Tkaczyk M.

Progress in Health Sciences

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2014

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tom 4

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nr 1

61-67

XX

Introduction: Mycophenolate mofetil (MMF) is used in treatment of idiopathic nephrotic syndrome in children (INS). Purpose: To evaluate clinical results of MMF treatment in steroid-dependent (SD) and steroid-resistant (SR) nephrotic syndrome. Materials and methods: A retrospective analysis of 26 patients (19 boys, 7 girls) with SDINS and SRINS treated with MMF during the years 2003–2013 was made. The remission length of INS and number of relapses per year before the introduction of MMF and after 12 months was calculated. An analysis of the side effects was made. Results: The median age of INS diagnosis was 26.5 months (IQRs 24-36 months). Nineteen of the patients (73%) suffered from SDINS whereas the remaining 7 (27%) had SRINS. Twenty three (88.5%) patients underwent renal biopsy: minimal change disease (MCD) in 69.6% (n=16), focal segmental glomerulosclerosis (FSGS) in 17.4% (n=4), membranoproliferative glomerulonephritis (MPGN) in 8.7% (n=2) and mesangial cell proliferation in one case. The median MMF dosage was 956.0 mg/m2/24h (IQRs 768.1-1059.7 mg/m2/24h). Eleven patients (42.3%) were taking MMF together with cyclosporine A (CsA). In patients suffering from SDINS, there was a trend to lower the recurrence rate during MMF treatment [2.0/year (IQRs 0.25-2.0 per year) vs 2.0/year (IQRs 1.0-2.75 per year), p=0.09]. Remission without proteinuria was significantly longer in patients treated with MMF; remission median was 8.5 month (IQRs 6.25-11.0 month) vs 4.5 month (IQRs 4.0-7.5 month), (p=0.014), similarly the average length of remission without corticosteroids was 6.0 months (IQRs 0.25-8.5 months) vs 3.0 months (IQRs 0.0-7.25) months (p=0.028). In children SRINS, 4/7 children MMF treatment was clinically ineffective. Side effects of the treatment were: leucopenia (n =10), hyperbilirubinemia (n = 3), gastrointestinal disorders (n = 1) and anemia (n = 1). Conclusion: This study confirmed the efficacy of the treatment with MMF in SDINR in comparison with previously used drugs, with a small number of side effects.

7

A family of symmetric stable-like processes and its global path properties

100%

Isozaki Y. , Uemura T.

Probability and Mathematical Statistics

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2004

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tom Vol. 24, Fasc. 1

145--164

EN

We extend the idea of the symmetric stable-like processes so that it includes the Brownian motion as well as the symmetric α-stable processes. We exhibit some sufficient conditions for their recurrence and conservativeness relying on the no-tion of Dirichlet forms. A criterion for conservativeness (Lemma 3.2) is also shown in terms of general Dirichlet forms and the associated generators.

8

Safety and efficacy of a Ventralight ST echo ps implant for a laparoscopic ventral hernia repair – a prospective cohort study with a one-year follow-up

88%

Stetsko T. , Bury K. , Lubowiecka I. , Szymczak C. , Tomaszewska A. , Śmietański M. , Stetsko T. , Bury K. , Lubowiecka I. , Szymczak C. , Tomaszewska A. , Śmietaski M.

Polish Journal of Surgery

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2016

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tom 88(1)

7-14

EN

Laparoscopic ventral hernia repair has become popular technique. Every year, companies are introducing new products Thus, every mesh prior to introduction in clinical settings should be tested with a dedicated tacker to discover the proper fixation algorithm. The aim of the study was to assess the safety and efficacy of the Ventralight ST implant with an ECHO positioning system and a dedicated fixation device, the SorbaFix stapler, in a prospective cohort of patients. Material and methods. The study was a prospective single centre cohort study with a one-year followup period. Fifty-two patients received operations for a ventral hernia using a laparoscopic IPOM mesh – Ventralight ST ECHO PS. The size of the mesh and the fixation method were based on mathematical considerations. A recurrence of the hernia and pain after 1, 2 and 12 months were assessed as the primary endpoints. Results. Two recurrences were noted, one in parastomal and one in a large incisional hernia. Pain was observed in 22 patients (41%) and mostly disappeared after 3 months (7%). The intensity of pain was low (VAS <2). However, 2 patients still experienced severe pain (VAS>6) until the end of the study. Conclusion. The Ventralight ST Echo PS implant fixed with a Sorbafix stapler is a valuable and safe option for a laparoscopic ventral hernia repair. In our opinion, the implant could be used in all patients due to the hernia ring diameter. According to the mathematical models and clinical practice, we do not recommend this implant in orifices with a width larger than 10 cm.

9

Triple thyroglossal duct cysts in an adult: a rare case report and review of literature

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Abhishek Bhardwaj A. , Kartikesh Gupta K. , Manu Malhotra M. , Madhu Priya M. , Mamta Verma M.

European Journal of Clinical and Experimental Medicine

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2020

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nr 2

121-126

EN

Introduction. Thyroglossal duct cyst (TDC) is the most common cause of congenital neck mass. These can present anywhere from foramen caecum to mediastinum. Usually presents as a solitary cyst, the double thyroglossal cyst is very rare and a triple thyroglossal cyst has never been reported. Aim. Herein, we report an atypical case of triple thyroglossal cyst, at levels of hyoid, thyrohyoid membrane and thyroid isthmus managed surgically without any complication. Description of the case. We are presenting case of a 48-year-old female who presented to us with the complaint of anterior neck swelling since birth. On work up it was diagnosed as a case of the thyroglossal duct cyst and was intraoperatively found to have 3 distinct cystic swellings connected to a common stalk lying beneath the hyoid. It was successfully treated by modified Sistrunk’s procedure. There was no evidence of recurrence on follow up for 6 months. Considering atypical presentations, there are 9 cases reported with the double thyroglossal duct cyst, TDC within the thyroid gland and sublingual TDC. Such presentations make the diagnosis more challenging, leading to improper treatment. Conclusion. We are presenting this case as there is no case reported in English literature with a triple thyroglossal duct cyst. An awareness that thyroglossal cyst can present as multiple cysts is important for clinician in order to perform correct surgical management and to avoid the most feared complication of recurrence.

10

Analysis of a stochastic difference equation: exit times and invariant distributions

75%

Högnäs G. , Jung B.

Fasciculi Mathematici

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2010

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tom Nr 44

69-74

EN

The mean return time of a discrete Markov chain to a point x is the reciprocal of the invariant probability π(x). We revisit this classical theme to investigate certain exit times for stochastic difference equations of autoregressive type. More specifically, we will discuss the asymptotics, as 0, of the first time that the n-dimensional process ...[wzór] (where ξ1, ξ2, . . . is a sequence of i.i.d. random n-vectors) leaves a given neighborhood of the fixed point of the contraction f.

11

Choroba Związana z Clostridium difficile u pacjentów hospitalizowanych w Centrum Medycznym w Łańcucie – badanie retrospektywne

75%

Musz-Kawecka M. , Hawro M. , Golec K.

Medical Review

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2013

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nr 3

342–355

PL

W związku z bardzo znacznym wzrostem zakażeń o etiologii C. difficile, w tym przede wszystkim zakażeń szpitalnych, zwiększa się zainteresowanie powyższym zagadnieniem oraz profilaktyką, diagnostyką i terapią Choroby Związanej z Clostridium difficile (CZCD) (1). Zakażenia związane z opieką zdrowotną stanowią dominującą część wszystkich zakażeń o etiologii C. difficile, co wynika zarówno z badań zewnętrznych (2) jak i z badań objętych tą pracą. Zakażenia szpitalne zależą od hospitalizacji i środowiska szpitalnego (3), dlatego ważne jest rozpoznanie sytuacji epidemiologicznej o etiologii C. difficile lokalnie w polskich szpitalach. Niniejsza praca analizuje zachorowalność na Chorobę Związaną z Clostridium difficile z zawężeniem do danych pochodzących z hospitalizacji w Centrum Medycznym w Łańcucie w latach 2009–2011. Przeprowadzane w ramach pracy badania wykazały, że badana populacja i środowisko odzwierciedla wyniki badań głównych ośrodków na świecie. Potwierdzono m.in. generalny wzrost zachorowalności wśród osób hospitalizowanych, zbieżność występowania czynników ryzyka, w tym związanych z wiekiem i antybiotykoterapią oraz częstość występowania przypadków nawrotów CZCD. Ponadto, zaobserwowano prawidłowości, wskazujące zakażenia C. difficile jako jedną z głównych przyczyn występowania biegunki u pacjentów hospitalizowanych. O istotności problemu zakażeń C. difficile świadczy również coraz częstsza liczba występowania przypadków CZCD w populacji pozaszpitalnej.

EN

Introduction: Due to a substantial increase in infections caused by Clostridium difficile, in particular hospital-acquired infections, an interest in this issue, as well as prevention, diagnosis and therapy of Clostridium difficile – associated Disease (CDAD) is increasing worldwide (1). Health-careassociated Clostridium difficile infections are prevalent among infections caused by Clostridium difficile, which results both from external study (2) and the research carried out and included in this work. Healthcare associated infections depend on hospitalization and hospital environment (3) so it is important to identify the epidemiological situation caused by Clostridium difficile in Polish hospitals. Aim: This work examines the incidence of Clostridium difficile – associated Disease, narrowing down the data to the ones obtained from the Medical Center in Łańcut in 2009–2011. Results: The research carried out shows that the studied population and the environment reflect the findings of the main world centers. A general increase in the incidence among hospitalized patients, the convergence of risk factors, including those age-related and connected with antibiotic therapy, and the incidence of recurrence have been confirmed. Furthermore, a certain regularity was observed, indicating that Clostridium difficile is one of the major causes of diarrhea in hospitalized patients. The significance of the problem of Clostridium difficile infection is also indicated by a growing number of CDAD incidence in a non-hospital population.

12

In vitro testing the potential of a novel chimeric IgG variant for inhibiting collagen fibrils formation in recurrent hereditary gingival fibromatosis: chimeric antibody in a gingival model

75%

Gawron K. , Lazarz-Bartyzel K. , Lazarz M. , Steplewska K. , Pyrc K. , Potempa J. , Chomyszyn-Gajewska M.

Journal of Physiology and Pharmacology

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2014

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tom 65

|

nr 4

13

Approximately linear recurrences

75%

Rasouli H. , Abbaszadeh S. , Eshaghi M.

Journal of Applied Analysis

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2018

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tom Vol. 24, nr 1

81--85

EN

In this paper, we present a Hyers–Ulam stability result for the approximately linear recurrence in Banach spaces. An example is given to show the results in more tangible form.

14

Comparison of properties of solutions of differential equations and recurrence equations with the same characteristic equation (on example of third order linear equations with constant coefficients)

75%

Mikołajski J. , Schmeidel E.

Opuscula Mathematica

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2006

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tom Vol. 26, no. 2

343-349

EN

Third order linear homogeneous differential and recurrence equations with constant coefficients are considered. We take the both equations with the same characteristic equation. We show that these equations (differential and recurrence) can have solutions with different properties concerning oscillation and boundedness. Especially the numbers of suitable types of solutions taken out from fundamental sets are presented. We give conditions under which the asymptotic properties considered are the same for the both equations.

15

Reoperative Surgery for Benign Thyroid Diseases

75%

Alesina P. , Rolfs T. , Walz M.

Polish Journal of Surgery

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2008

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tom 80

|

nr 9

441-445

EN

The aim of the study was to present a retrospective analysis of the experience with completion thyroidectomy for benign thyroid disease in a referral centre.Material and methods. Between October 1999 and December 2007, 2353 thyroid operations were performed for benign diseases. Of these, 113 patients (12 men, 101 women; age: 25-77 years) underwent a reoperation for recurrent goitre (n=107) or recurrent Grave's disease (n=6). A bilateral resection was performed in 33 patients, a unilateral in 80 patients. The mean interval between the initial and the reoperative procedure was 14.5 years.Results. The mean operative time was 78 minutes (range: 20-210) with 68 minutes for unilateral and 96 minutes for bilateral operations. Postoperative complications consisted of transient hypoparathyroidism in 6 patients (5.3%); no patient experienced a permanent hypoparathyroidism. A transient recurrent laryngeal nerve (RLN) palsy occurred in 6 cases (4.1% of "nerves at risk") and a definitive bilateral RLN palsy was registered in a patient with a preoperative unilateral RLN palsy (0.9%). In 4 patients (3.5%) a postoperative bleeding required reoperation. No wound infection was observed. The mean postoperative hospital stay was 2.3 days. Final histology showed a thyroid cancer in 6 patients (5.3%).Conclusion. In experienced hands, reoperative thyroid surgery can be performed safely and with limited morbidity.

16

Radial internal clearance analysis in ball bearings

75%

Ambrożkiewicz B. , Syta A. , Meier N. , Litak G. , Georgiadis A.

Eksploatacja i Niezawodność

|

2021

|

tom Vol. 23, no. 1

42--54

EN

Radial internal clearance (RIC) is one of the most important parameters influencing on rolling bearing exploitation in mechanical systems. Lifetime of rotary machines strongly depends on a condition of applied rolling elements, thus a study on applied clearance is very important in terms of maintenance and reliability. This paper proposes, a novel approach of studying RIC, based on a nonlinear dynamics method called recurrences. The results are confronted with standard analyses, i.e. statistical condition indicators, Fast Fourier Transform and Continuous Wavelet Transform. The application of the mentioned methods allowed us to find the optimal radial clearance for operating bearings. To ensure precise measurements of the clearance, an automated setup for RIC measurements is applied and next mounted in a plummer block and tested to finally measure vibration acceleration. The proposed methods are useful for a condition monitoring and lifetime prediction of bearings or bearing-based systems in which a proper value of radial clearance is crucial.

17

A note on invariant sets

75%

Schilling R. L.

Probability and Mathematical Statistics

|

2004

|

tom Vol. 24, Fasc. 1

47--66

EN

A measurable set A is invariant with respect to a not necessarily symmetric sub-Markovian operator T on Lp (X, m) if T1A ≤ 1A, and strongly invariant if T1A = 1A. We show that these definitions accommodate many of the usual definitions of invariance, e.g., those used in Dirichlet form theory, ergodic theory or for stochastic processes. In finite measure spaces or if T∗ is sub-Markovian and recurrent, the notions of invariance and strong invariance coincide. We also show that for certain analytic semigroups of sub-Markovian operators, (strongly) invariant sets are already determined by a single operator, T1.

18

Textgrammatika in einer Beschwerdeschrift Johann Geilers von Kaysersberg: Zur religiösen Identität und zum juridischen Selbstverständnis im späten Mittelalter

75%

Seyferth S.

Studia Linguistica

|

2014

|

nr 33

123 - 134

EN

The article deals with textual phenomena such as isotopy, recurrence or contiguity within a late medieval text, the so-called 21 articles from 1501 written by Johann Geiler von Kaysersberg. The famous preacher argues against heretic judicial instructions initiated by Strasbourg’s city council. Lexically, Geiler focuses on a certain “judgmental concept” in which he accuses, warns, japes, moderates or constructively proposes his point of view. To sum up, he frequently uses rhetorical features in order to write intelligibly.

19

A recurrence theorem for square-integrable martingales

75%

Alsmeyer G.

Studia Mathematica

|

1994

|

tom 110

|

nr 3

221-234

EN

Let $(M_n)_{n≥0}$ be a zero-mean martingale with canonical filtration $(ℱ_n)_{n≥0}$ and stochastically $L_2$-bounded increments $Y_1,Y_2,..., $ which means that $P(|Y_n| > t | ℱ_{n-1}) ≤ 1 - H(t)$ a.s. for all n ≥ 1, t > 0 and some square-integrable distribution H on [0,∞). Let $V^2 = ∑_{n≥1} E(Y_{n}^{2}|ℱ_{n-1})$. It is the main result of this paper that each such martingale is a.s. convergent on {V < ∞} and recurrent on {V = ∞}, i.e. $P(M_{n} ∈ [-c,c] i.o. | V = ∞) = 1$ for some c > 0. This generalizes a recent result by Durrett, Kesten and Lawler [4] who consider the case of only finitely many square-integrable increment distributions. As an application of our recurrence theorem, we obtain an extension of Blackwell's renewal theorem to a fairly general class of processes with independent increments and linear positive drift function.

20

Work stress and the risk of recurrent coronary heart disease events: A systematic review and meta-analysis

75%

Li J. , Zhang M. , Loerbroks A. , Angerer P. , Siegrist J.

International Journal of Occupational Medicine and Environmental Health

|

2015

|

tom 28

|

nr 1

8-19

EN

Though much evidence indicates that work stress increases the risk of incident of coronary heart disease (CHD), little is known about the role of work stress in the development of recurrent CHD events. The objective of this study was to review and synthesize the existing epidemiological evidence on whether work stress increases the risk of recurrent CHD events in patients with the first CHD. A systematic literature search in the PubMed database (January 1990 – December 2013) for prospective studies was performed. Inclusion criteria included: peer-reviewed English papers with original data, studies with substantial follow-up (> 3 years), end points defined as cardiac death or nonfatal myocardial infarction, as well as work stress assessed with reliable and valid instruments. Meta-analysis using random-effects modeling was conducted in order to synthesize the observed effects across the studies. Five papers derived from 4 prospective studies conducted in Sweden and Canada were included in this systematic review. The measurement of work stress was based on the Demand- Control model (4 papers) or the Effort-Reward Imbalance model (1 paper). According to the estimation by meta-analysis based on 4 papers, a significant effect of work stress on the risk of recurrent CHD events (hazard ratio: 1.65, 95% confidence interval: 1.23–2.22) was observed. Our findings suggest that, in patients with the first CHD, work stress is associated with an increased relative risk of recurrent CHD events by 65%. Due to the limited literature, more well-designed prospective research is needed to examine this association, in particular, from other than western regions of the world.