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2013 | 67 | 1 | 67-73
Tytuł artykułu

Aspiryna – 115 lat po odkryciu

Treść / Zawartość
Warianty tytułu
EN
Aspirin – 115 years after the discovery
Języki publikacji
PL
Abstrakty
EN
Aspirin has been known as a commercial drug for over a century, however, a much deeper understanding of its mechanism of action as an inhibitor of cyclooxygenase (COX) activity and thus, of prostanoid synthesis, is still lacking. Recent advances in understanding the central role of platelets in the pathophysiology of cardiovascular diseases and the identification of novel lipid mediators synthesized in the presence of aspirin have increased research upon the mechanisms of aspirin action.
PL
Aspiryna jest lekiem dostępnym komercyjnie od ponad stu lat, chociaż wciąż brakuje głębszego zrozumienia mechanizmu jej działania jako inhibitora aktywności cyklooksygenazy i syntezy prostanoidów. Niedawne odkrycia dotyczące centralnej roli płytek krwi w patofizjologii chorób układu sercowo-naczyniowego oraz identyfikacja nowych mediatorów lipidowych syntetyzowanych w obecności aspiryny nasiliły badania nad mechanizmami działania aspiryny.
Słowa kluczowe
Wydawca

Rocznik
Tom
67
Numer
1
Strony
67-73
Opis fizyczny
Twórcy
  • Katedra i Zakład Biochemii Wydziału Farmaceutycznego z Oddziałem Medycyny Laboratoryjnej Śląskiego Uniwersytetu Medycznego w Katowicach ul. Narcyzów 1 41-200 Sosnowiec tel. +48 32 364 10 03, e-mail: epimer@wp.pl
  • Katedra i Zakład Biochemii Wydziału Farmaceutycznego z Oddziałem Medycyny Laboratoryjnej Śląskiego Uniwersytetu Medycznego w Katowicach
Bibliografia
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Typ dokumentu
article
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.psjd-03b43291-014d-4ab7-91da-71cc06a10bfb
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