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Tytuł artykułu

Cellular aspects of folate and antifolate membrane transport

Warianty tytułu
Języki publikacji
Folates one carbon carriers take part in the metabolism of purine, thymidylate and some amino acids. Internalization of these compounds employs several mechanisms of transport systems. Reduced folate carriers and folate receptors play the most important role in this process. The physiological role of these molecules in normal and neoplastic cells is described regarding changes in transport activity and connection of transport systems with resistance to antifolates and cancer development.
Opis fizyczny
  • Polish Academy of Sciences, L.Pasteura 3, 02-093 Warsaw, Poland
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