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2007 | 79 | 12 | 762-772
Tytuł artykułu

Hand Transplantation: The Milan Experience

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The authors describe the most critical aspects of transplantation of the hand. Three successful cases are presented from the Italian Hand Transplantation National Program. The key issues of this new type of surgical reconstruction for major amputations are selection criteria of suitable candidates, technical aspects of surgery, postoperative regime and functional rehabilitation. Other important aspects are staff requisites and organisation of the clinical trial, ethical and legal implications, dealing with the media. The authors comment on the fact that we might be ready to accept that almost anything could come from a cadaver, even if it is not a life-saving organ, to reconstruct missing parts and restore anatomical integrity and, especially, function.
Słowa kluczowe
Wydawca

Rocznik
Tom
79
Numer
12
Strony
762-772
Opis fizyczny
Daty
wydano
2007-12-01
online
2008-02-11
Twórcy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
autor
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
autor
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
autor
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
  • Hand Surgery and Reconstructive Microsurgery, Unit San Gerardo Hospital, Monza University of Milan-Bicocca, Italy
Bibliografia
  • Lanzetta M, Nolli R, Borgonovo A et al.: Hand transplantation: Immunosuppression, ethics and indications. J Hand Surg (B) 2002; 26B: 511.
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  • Graham B, Adkins P, Tsai TM et al.: Major replantation versus revision amputation and prosthetic fitting in the upper extremity: a late functional outcomes study. J Hand Surg [Am] 1989; 23(5): 783-91.
  • Gasperschitz F, Genelin F, Karlbauer A et al.: Decrease in disability pension following replantation. Handchir Mikrochir Plast Chir 1990; 22(2): 78-81.[PubMed]
  • Peters DH, Fitton A, Plosker GL: A review of its pharmacology, and therapeutic potential in hepatic and renal transplantation. Drugs 1993; 46: 746.[Crossref][PubMed]
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  • Gold BG, Storm-Dickerson T, Austin DR: The immunosuppressant FK506 increases functional recovery and nerve regeneration following peripheral nerve injury. Rest Neurol Neurosci 1993; 6: 287.
  • Flor H, Elbert T, Knecht S et al.: Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. Nature 1995; 375: 482.
  • Ramachandran VS, Rogers-Ramachandran D et al.: Correlates of massive cortical reorganization. Science 1992; 258: 1159.
  • Giraux P, Sirigu A, Schneider F et al.: Cortical reorganization in motor cortex after graft of both hands. Nature Neuroscience 2001; 4: 1.
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  • Stark GB, Swartz WM, Narayanan K: Hand transplantation in baboons. Transpl Proc 1987; 19: 3968.
  • Egersezi EP, Samulack DD, Daniel RK: Experimental models in primates for reconstructive surgery utilizing tissue transplants. Ann Plast Surg 1984; 13: 423.[Crossref]
  • Hovius SER, Stevens HPJD, Van Nierop PWM: Allogenic transplantation of the radial side of the hand in the rhesus monkey. Plast Reconstr Surg 1992; 89: 700.[Crossref]
  • Benhaim P, Anthony JP, Ferreira L et al.: Use of combination of low-dose Cyclosporine and RS61443 in a rat hind limb model of composite tissue allotransplantation. Transplant 1996; 61: 527.[Crossref]
  • Llull R: An open proposal for clinical composite tissue transplantation. Transpl Proc 1998; 30: 2692.[Crossref]
  • Hewitt CW: Update and outline of the experimental problems facing clinical composite tissue transplantation. Transpl Proc 1998; 30: 2704.[Crossref]
  • Saltonstall R: Healthy bodies, social bodies: men's and women's concepts and practices of health in everyday life. Soc Sci Med 1993; 36(1): 7-14.[Crossref]
  • Zerbe KJ: Anorexia nervosa and bulimia nervosa. When the pursuit of bodily ≪perfection≫ becomes a killer. Postgrad Med 1996; 99(1): 161-4: 167-69.
  • Beasley RW, de Bese GM: Upper limb amputations and prostheses. Orthop Clin North Am 1986; 17(3): 395-405.[PubMed]
  • Evans RW, Manninen DL, Garrison LP Jr. et al.: The quality of life of patients with end-stage renal disease. N Engl J Med 1985, 28; 312(9): 553-59.
  • Gross CR, Zehrer CL: Health-related quality of life outcomes of pancreas transplant recipients. Clin Transplant 1992; 6(3 part 1): 165-71.[PubMed]
  • Zehr PS, Milde FK, Hart LK: Pancreas transplantation: assessing secondary complications and life quality. Diabetologia 34 Suppl 1991; 1: 138-40.[Crossref]
  • Asencio G, Abihaidar G, Leonardi C: Human composite flexor tendon allografts. A report of two cases. J Hand Surg [Br] 1996; 21(1): 84-88.[Crossref]
  • Carpenter JP, Tomaszewski JE: Immunosuppression for human saphenous vein allograft bypass surgery: a prospective randomized trial. J Vasc Surg 1997; 26(1): 32-42.[Crossref][PubMed]
  • Hofmann GO, Kirschner MH, Gonschorek O: V Bridging long bone and joint defects with allogeneic vascularized transplants. Langenbecks Arch Chir Suppl Kongressbd 1989; 115: 1285-87.
  • Jones TR, Humphrey PA, Brennan DC: Transplantation of vascularized allogeneic skeletal muscle for scalp reconstruction in renal transplant patient. Transplant Proc 1998; 30(6): 2746-53.[PubMed][Crossref]
  • Mackinnon SE, Hudson AR: Clinical application of peripheral nerve transplantation. Plast Reconstr Surg 1992; 90(4): 695-99.[Crossref][PubMed]
  • Gallagher S, Butterworth GE, Lew A et al.: Cole J Hand-mouth coordination, congenital absence of limb, and evidence for innate body schemas. Brain Cogn 1998; 38(1): 53-65.[Crossref]
  • Melzack R: Phantom limbs and the concept of a neuromatrix. Trends Neurosci 1990; 13(3): 88-92.[PubMed][Crossref]
  • Moore TJ, Barron J, Hutchinson F 3rd: DP rosthetic usage following major lower extremity amputation. Clin Orthop Relat Res 1989; 238: 219-24.
  • Folsom D, King T, Rubin JR: Lower-extremity amputation with immediate postoperative prosthetic placement. Am J Surg 1992; 164(4): 320-22.[PubMed][Crossref]
  • Macklin R: Understanding informed consent. Acta Oncol 1999; 38(1): 83-87.[Crossref][PubMed]
  • Alderson P: Informed consent: ideal or reality? J Health Serv Res Policy 1998; 3(2): 124-26.
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  • Dubernard JM, Owen ER, Herzberg G et al.: Human hand allograft: report on first 6 months. Lancet 1999; 353: 1315.
  • Dubernard JM, Owen ER, Lanzetta M et al.: What is happening with hand transplants? Lancet 2000; 1357: 1711.
  • Dubernard JM, Owen ER, Lefrancois N et al.: First human hand transplantation. Case report. Transpl Int 2000; 13: 521.
  • Jones JW, Gruber SA, Barker JH et al.: Successful hand transplantation. One-year follow-up. N Engl J Med 2000; 343: 468.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_v10035-007-0118-3
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