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2010 | 12 | 2 | 38-45
Tytuł artykułu

Influence of the coating process parameters on the quality of PUR/PVP hydrogel coatings for PVC medical devices

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
To decrease friction factor and enhance the biocompatibility of medical devices manufactured from poly(vinyl chloride), PVC, the surface modification with wear resistant polyurethane/polyvinylpyrrolidone (PUR/PVP) hydrogel coating can be applied. In the present work substrates were dip-coated with PVP and PUR solutions and thermally cured. The variable process parameters were: solvent system; concentration of polymers (1, 2 or 3% w/v); coating baths temperature (22, 38 and 55°C); drying temperature (32, 50 and 67°C); length of break between process steps (5, 30 and 90 s); and solutions storage time (up to 72 hrs). The quality of coatings was determined by friction coefficients against porcine aorta, weights of the deposited layer and the swelling capacity. The solvent system and polymers concentration were crucial factors. The increased temperature of coating solutions caused increased deposition but decreased durability. The most lubricious samples were dried in 50°C. Coatings from the solutions prepared 24h prior to use had better properties than those from fresh solutions.
Wydawca

Rocznik
Tom
12
Numer
2
Strony
38-45
Opis fizyczny
Daty
wydano
2010-01-01
online
2010-07-09
Twórcy
  • The Faculty of Chemical and Process Engineering, Warsaw University of Technology, ul. Warynskiego 1, 00-645 Warszawa, Poland
  • The Faculty of Chemical and Process Engineering, Warsaw University of Technology, ul. Warynskiego 1, 00-645 Warszawa, Poland
autor
  • The Faculty of Chemical and Process Engineering, Warsaw University of Technology, ul. Warynskiego 1, 00-645 Warszawa, Poland
Bibliografia
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  • Karadag, E., Üzüm, Ö. B. & Saraydin, D. (2005). Water uptake in chemically crosslinked poly(acrylamide-co-crotonic acid) hydrogels. Mater. Des. 26(4), 265-270. DOI: 10.1016/j.materdes.2004.07.014.[Crossref]
  • Wichterle, O. & Lim, D. (1960). Hydrophilic gels for biological use. Nature 185, 117-118. DOI: 10.1038/185117a0.[Crossref]
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  • Tunney, M. M. & Gorman, S. P. (2002). Evaluation of a poly(vinyl pyrollidone)-coated biomaterial for urological use. Biomaterials 23(23), 4601-4608. DOI: 10.1016/S0142-9612(02)00206-5.[PubMed][Crossref]
  • Yang, S. H., Lee, Y. S., Lin, F. H., Yang, J. M. & Chen, K. S. (2007). Chitosan/poly(vinyl alcohol) blending hydrogel coating improves the surface characteristics of segmented polyurethane urethral catheters. J. Biomed. Mater. Res. B Appl. Biomater. 83(2), 304-313. DOI: 10.1002/jbm.b.30796[Crossref][WoS]
  • LaPorte, R. J. (1997). Hydrophilic polymer coatings for medical devices: structure/ properties, development, manufacture, and applications. Boca Raton, USA: CRC Press.
  • Micklus, M. J & Ou-Yang, D. T. (1978). U. S. Patent No. 4,100,309. Washington, D. C.: U. S. Patent and Trademark Office.
  • Kaźmierska, K., Szwast, M. & Ciach, T. (2008). Determination of urethral catheter surface lubricity. J. Mater. Sci. Mater. Med. 19(6), 2301-2306. DOI: 10.1007/s10856-007-3339-4.[Crossref]
  • Kaźmierska, K., A., Kuc, K. & Ciach, T. (2008). Polyvi-nylpyrrolidone-polyurethane interpolymer hydrogel coating as a local drug delivery system. Acta Pol. Pharm. 65(6), 763-766. Retrieved January 28, 2010, from http://www.ptfarm.pl/ pub/File/acta_pol_2008/6_2008/763-766.pdf.
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_v10026-010-0016-z
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