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2008 | 14 | 1 | 1-12
Tytuł artykułu

Free radicals in a conglomerate of peripheral blood with a spin trap investigated by the EPR method before and after angioplasty treatment

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The Electron Paramagnetic Resonance (EPR) was used to investigate free radicals in the peripheral blood of patients subjected to angioplasty treatment. To detect these free radicals, a nitrosobenzene spin trap was used in this experiment. The EPR spectra of the blood with a spin trap conglomerate was measured at room temperature and at 170 K. To confirm the kind of free radicals in the conglomerate blood-spin trap, simulation and quantum-chemical calculations were made, and the conglomerate spin trap with ascorbic acid was measured. Two different types of radicals, one at room temperature and the other in a frozen sample of blood, were found.
Wydawca

Rocznik
Tom
14
Numer
1
Strony
1-12
Opis fizyczny
Daty
wydano
2008-01-01
online
2008-12-29
Twórcy
  • Faculty of Physics, Medical Physics Division, Adam Mickiewicz University, Umultowska 85, 61-614 Poznan, Poland
  • Faculty of Physics, Medical Physics Division, Adam Mickiewicz University, Umultowska 85, 61-614 Poznan, Poland
  • Regional Hospital, Kielce, Poland
  • Faculty of Physics, Medical Physics Division, Adam Mickiewicz University, Umultowska 85, 61-614 Poznan, Poland
Bibliografia
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  • Mottley C, Kalyanaraman B, Mason RP. Spin Trapping Artifacts due to the Reduction of Nitroso Spin Traps. FEBS Letters. 1981; 130(1): 12-14.
  • Owenius R, Engstrom M, Lindgren M, Huber M. Influence of Solvent Polarity and Hydrogen Bonding on the EPR Parameters of a Nitroxide Spin Label Studied by 9-GHz EPR Spectroscopy and DFT Calculations. J Phys Chem A. 2001; 105: 10967-10977.
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  • Ytrehus K, Hegstad AC. Lipid peroxidation and membrane damage of heart. Acta Physiol Scand. 1991; S599: 81-91.
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  • Zweier JL, Kuppusamy P, Williams R, Rayburn BK, Smith D, Weisfeldt ML, Flaherty JT. Measurement and Characterization of Postischemic Free Radical Generation in the Isolated Perfused Heart. J Biol Chem. 1989; 264(32): 18890-18895.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_v10013-008-0001-5
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