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2014 | 9 | 1 | 144-147
Tytuł artykułu

Disseminated tuberculosis in an immunocompetent patient

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
A 53-year-old immigrant male patient presented with left scrotal swelling with a draining ulcer on the left hemiscrotum. Patient had intentional weight loss, fever and night sweats, cough, headaches, confusion and difficulty with ambulation. Imaging studies revealed innumerable pulmonary nodules, leptomeningeal enhancement of the brain and bilateral epididymo-orchitis. Acid fast bacilli (AFB) smear was positive from the surgical specimen of bilateral epididymis and left testes. Cerebrospinal fluid (CSF) analysis revealed neutrophilic predominant pleocytosis with low glucose and elevated protein. Polymerase chain reaction (PCR) test performed on the CSF and AFB smear of epididymis was positive for Mycobacterium tuberculosis. Though the CSF and sputum AFB smears were negative, cultures subsequently grew mycobacterium tuberculosis. Patient was diagnosed with disseminated tuberculosis. Human deficiency virus test was negative. Patient was successfully treated with anti-tuberculosis therapy. Steroid was used as adjuvant therapy due to presence of tuberculous meningitis.
Wydawca

Czasopismo
Rocznik
Tom
9
Numer
1
Strony
144-147
Opis fizyczny
Daty
wydano
2014-02-01
online
2014-02-04
Twórcy
  • Division of Infectious Diseases, Scott and White Memorial Hospital, Temple, TX, 76508, USA, sranganath@sw.org
  • Department of Internal Medicine, Scott and White Memorial Hospital, Temple, TX, 76508, USA
  • Division of Infectious Diseases, Scott and White Memorial Hospital, Temple, TX, 76508, USA
autor
  • Division of Infectious Diseases, Scott and White Memorial Hospital, Temple, TX, 76508, USA
Bibliografia
  • [1] Charfi MR, Dougui MH, Louzir B, Mestiri A, Zbiba M, Belalgia MS, et al. Disseminated tuberculosis in non-immunocompromised host: three case reports. Rev Med Interne. 1998 Dec; 19(12):917–920 http://dx.doi.org/10.1016/S0248-8663(99)80065-4[Crossref]
  • [2] Seif F, Armitage K, Petrozzi M. Unusual presentation of a common disease: disseminated tuberculosis in an immunocompetent patient. Am J med 2010; 2010 Sep;123(9):e5–e7. doi: 10.1016/j.amjmed.2010.01.021 [Crossref]
  • [3] Kishore PV, Palaian S, Paudel R, Prabhu M, Van den Ende J. Diagnostic Delay in a Multi-Organ Tuberculosis Immunocompetent Patient: A Case Report. Southeast Asian J Trop Med Public Health. 2007 May;38(3):507–511
  • [4] Phypers M, Harris T, Power C. CNS tuberculosis: a longitudinal analysis of epidemiological and clinical features. Int J Tuberc Lung Dis. 2006 Jan;10(1):99–103 [PubMed]
  • [5] Rock RB, Olin M, Baker CA, Molitor TW, Peterson PK. Central nervous system tuberculosis: Pathogenesis and clinical aspects. Clin Microbiol Rev. 2008 Apr;21(2):243–261, table of contents. doi: 10.1128/CMR.00042-07 http://dx.doi.org/10.1128/CMR.00042-07[WoS][Crossref]
  • [6] Donald PR, Schoeman JF. Tuberculous Meningitis. N Engl J Med. 2004 Oct 21;351(17):1719–1720 http://dx.doi.org/10.1056/NEJMp048227[Crossref]
  • [7] Daikos GL, Cleary T, Rodriguez A, Fischl MA. Multidrug-resistant tuberculous meningitis in patients with AIDS. Int J Tuberc Lung Dis. 2003 Apr;7(4):394–398 [PubMed]
  • [8] Nelson CA, Zunt JR. Tuberculosis of the central nervous system in immunocompromised patients: HIV infection and solid organ transplant recipients. Clin Infect Dis. 2011 Nov;53(9):915–926. doi: 10.1093/cid/cir508. Epub 2011 Sep 29 http://dx.doi.org/10.1093/cid/cir508[PubMed][Crossref]
  • [9] Shenoy VP, Viswanath S, D’Souza A, Bairy I, Thomas J. Isolated epididymo-orchitis is an unusual presentation of tuberculosis. J Infect Dev Ctries. 2012 Jan 12;6(1):92–94 http://dx.doi.org/10.3855/jidc.2145[Crossref]
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11536-013-0261-7
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