Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2013 | 8 | 4 | 499-502
Tytuł artykułu

Progressive course of isolated splenic myeloid sarcoma

Treść / Zawartość
Warianty tytułu
Języki publikacji
A previously healthy 40-year-old male presented with a 2-week history of fever and abdominal discomfort that was resistant to empirical broad-spectrum antibiotic treatment. The patient’s blood cell count and complete biochemical panel was normal, except for an increased lactate dehydrogenase level. Ultrasonography and computed tomography of the abdomen showed a large, soft tissue mass had infiltrated superior part of the spleen. Splenectomy with total tumor mass removal were performed. The pathological examination of the tumor tissue confirmed diagnosis of isolated myeloid sarcoma with monoblastic differentiation. Despite intensive antileukemic therapy, patient died four months after diagnosis was established.
Słowa kluczowe

Opis fizyczny
  • Clinic for Hematology, Clinical Center Serbia, Belgrade, Serbia
  • Clinic for Digestive Surgery, Clinical Center Serbia, Belgrade, Serbia
  • [1] Pileri SA, Orayi A, Falini B: Myeloid sarcoma. In Swerdlow S, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (eds) WHO classification of tumours of haematopoetic and lymphoid tissues. Lyon, IARC, 2008, pp 140–141
  • [2] Burns A. Observation of surgical anatomy, head and neck. Edinburgh: Thomas Royce and co;1811, pp 364–366
  • [3] King A. A case of chloroma. Monthly J med 1853;17:97
  • [4] Rappaport H. Tumors of the hematopoetic system. Armed Forces Inst Pathol 1966; 241–243
  • [5] Hutchinson RE, Kurec AS, Davey FR. Granulocytic sarcoma. Clin Lab Med. 1990; 10; 889–901
  • [6] Paydas S, Zorludemir S, Ergin M. Granulocytic sarcoma: 32 cases and review of the literature. Leuk Lymphoma. 2006; 47(12)
  • [7] Antic D, Verstovsek S, Elezovic I, Grujicic D, Gotic M, Bila J et al. Spinal epidural granulocytic sarcoma in non-leukemic patient. Int J Hematol. 2009 Jan;89(1):95–97[WoS][Crossref]
  • [8] Antic D, Elezovic I, Bogdanovic A, Vukovic NS, Pavlovic A, Jovanovic MP Isolated myeloid sarcoma of the gastrointestinal tract. Intern Med. 2010;49(9):853–856[WoS][Crossref]
  • [9] Audouin J, Comperat E, Le Tourneau A, Camilleri-Broët S, Adida C, Molina T et al. Myeloid sarcoma: clinical and morphologic criteria useful for diagnosis Int J Surg Pathol. 2003; 11(4):271–282[Crossref]
  • [10] Alexiev BA, Wang W, Ning Y, Chumsri S, Gojo I, Rodgers WH et al. Myeloid sarcomas: a histologic, immunohistochemical, and cytogenetic study. Diagn Pathol. 2007; 2:42[Crossref]
  • [11] Klco JM, Welch JS, Nguyen TT, Hurley MY, Kreisel FH, Hassan A et al. State of the art in myeloid sarcoma. Int J Lab Hematol. 2011;33(6):555–565[Crossref][WoS]
  • [12] Breccia M, Mandelli F, Petti MC, D’Andrea M, Pescarmona E, Pileri SA et al. Clinicopathological characteristics of myeloid sarcoma at diagnosis and during follow-up: report of 12 cases from a single institution. Leuk Res. 2004; 28(11):1165–1169[Crossref]
  • [13] Rund D, Azar I, Shperling O. A mutation in the promoter of the multidrug resistance gene (MDR1) in human hematological malignancies may contribute to the pathogenesis of resistant disease. Adv Exp Med Biol. 1999;457:71–75[Crossref]
  • [14] Bakst RL, Tallman MS, Douer D, Yahalom J. How I treat extramedullary acute myeloid leukemia. Blood. 2011;118(14):3785–3793[Crossref]
  • [15] Meis JM, Butler JJ, Osborne BM, Manning JT. Granulocytic sarcoma in nonleukemic patients. Cancer. 1986; 58(12):2697–2709<2697::AID-CNCR2820581225>3.0.CO;2-R[Crossref]
  • [16] Byrd, J.C., Edenfield, W.J., Shields, D.J. and Dawson, N.A. Extramedullary myeloid cell tumors in acute nonlymphocytic leukemia: A Clinical Review J. Clin. Oncol. 1995; 13(7), 1800–1816
  • [17] Neiman RS, Barcos M, Berard C, Bonner H, Mann R, Rydell RE et al. Granulocytic sarcoma: a clinicopathologic study of 61 biopsed cases. Cancer 1981;48: 1426–1437<1426::AID-CNCR2820480626>3.0.CO;2-G[Crossref]
  • [18] Yamauchi K, Yasuda M. Comparison in treatments of nonleukemic granulocytic sarcoma: report of two cases and a review of 72 cases in the literature. Cancer. 2002; 94(6):1739–1746[Crossref]
  • [19] Tsimberidou AM, Kantarjian HM, Wen S, Keating MJ, O’Brien S, Brandt M et al. Myeloid sarcoma is associated with superior event-free survival and overall survival compared with acute myeloid leukemia. Cancer. 2008; 113(6):1370–1378[Crossref]
  • [20] Pileri SA Ascani S, Cox MC, Campidelli C, Bacci F, Piccioli M et al. Myeloid sarcoma: clinico pathologic, phenotypic and cytogenetic analysis of 92 adult patients. Leukemia. 2007; 21(2):340–350[Crossref][WoS]
  • [21] Lan TY, Lin DT, Tien HF, Yang RS, Chen CY, Wu K. Prognostic factors of treatment outcomes in patients with granulocytic sarcoma. Acta Haematol. 2009;122(4):238–246[Crossref]
  • [22] Antic D, Elezovic I, Milic N, Suvajdzic N, Vidovic A, Perunicic M et al. Is there a “gold” standard treatment for patients with isolated myeloid sarcoma? Biomed Pharmacother. 2013;67(1):72–77[Crossref][WoS]
  • [23] Chevallier P, Labopin M, Cornelissen J, Socié G, Rocha V, Mohty M; ALWP of EBMT. Allogeneic hematopoietic stem cell transplantation for isolated and leukemic myeloid sarcoma in adults: a report from the Acute Leukemia Working Party of the European group for Blood and Marrow Transplantation. Haematologica.2011;96(9):1391–1394[Crossref]
Typ dokumentu
Identyfikator YADDA
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.