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2012 | 7 | 1 | 112-117
Tytuł artykułu

Insomnia severity in chronic kidney disease patients with various therapies

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The prevalence of insomnia is greater in end-stage renal disease. The aim of our study was to determine the frequency of insomnia and subclinical insomnia in patients with various dialysis therapy and kidney transplant recipients, in order to assess the severity of insomnia and examine whether there is a difference in severity among groups. In cross-sectional study, we evaluated 120 patients with terminal renal failure. Based on therapy, patients were divided into four groups: hemodiafiltration, standard bicarbonate dialysis, peritoneal dialysis and kidney transplant recipients. The severity of insomnia was evaluated through the use of the Insomnia Severity Index (ISI). Most patients who reported any kind of insomnia problems with ISI were on conventional dialysis (80%), followed by hemodiafiltration (76.7%) and peritoneal dialysis (63.3%). Transplant recipients had least difficulties with insomnia (46.7%). Insomnia Severity Index showed that insomnia in end-stage renal patients is not very severe. Most of the patients had “no clinically significant insomnia”. Our findings indicate that patients on hemodiafiltration and transplant recipients have a significantly lower score on Insomnia Severity Index. Patients with end-stage renal disease have high frequency insomnia problems. However, our study shows that insomnia in these patients is not severe. Insomnia is the most frequent and severest in patients on standard bicarbonate dialysis.

Opis fizyczny
  • Clinic of Mental Health Protection, Clinical centre Nis, Zorana Djindjica 48, Nis, 18 000, Serbia
  • Medical Faculty, University of Kragujevac, Svetozara Markovica 69, Kragujevac, 34 000, Serbia
  • Health Center Uzice, Primary Health Care Center, Jug Bogdanova 4, Uzice, 31 000, Serbia
  • Clinic of Nephrology, Clinical centre Nis, Zorana Djindjica 48, Nis, 18 000, Serbia
  • [1] World Health Organization, The ICD-10 Classification of Mental and Behavioural Disorders, Diagnostic criteria for research, Geneva, 1993
  • [2] Gusbeth-Tatomir P., Boisteanu D., Seica A., Buga C., Covic A., Sleep disorders: a systematic review of an emerging major clinical issue in renal patients, Int. Ur ol. Nephrol., 2007, 39, 1217–1226[Crossref]
  • [3] Noda A., Nakai S., Soga T., et al., Factors contributing to sleep disturbance and hypnotic drug use in hemodialysis patients, Intern. Med., 2006, 45, 1273–1278[Crossref]
  • [4] Musci I., Molnar M.Z., Rethelyi J., et al., Sleep disorders and illness intrusivness in patients on chronic dialysis, Nephrol. Dial. Transplant., 2004, 19, 1815–1822[Crossref]
  • [5] Williams S.W., Tell G.S., Zheng B., Shumaker S., Rocco MV., Sevick MA., Correlates of sleep behavior among hemodialysis patients. The kidney outcomes prediction and evaluation (KOPE) study, Am. J. Nephrol., 2002, 22, 18–28[Crossref]
  • [6] Adbelwhab S., Kamel M., Noshey M., Sleep disorders in hemodialysis patients, Kidney., 2010, 19, 175–181[Crossref]
  • [7] Merlino G., Piani A., Dolso P., et al., Sleep disorders in patients with end-stage renal disease undergoing dialysis therapy, Nephrol. Dial. Transplant., 2006, 21, 184–190[Crossref]
  • [8] Iliescu E.A., Coo H., McMurray M.H., et al., Quality of sleep and health-related quality of life in haemodialysis patients, Nephrol. Dial. Transplant., 2003, 18, 126–132[Crossref]
  • [9] Cengic B., Resic H., Spasovski G., Avdic E., Alajbegovic A., Quality of sleep in patients undergoing hemodialisys, Int. Urol. Nephrol., 2010, (Epub ahead of print)
  • [10] Eryavuz N., Yuksel S., Acarturk G., et al., Comparasion of sleep quality between hemodialysis and peritoneal dialysis patients, Int. Urol. Nephrol., 2008, 40, 785–791[Crossref]
  • [11] Sabbatini M., Minale B., Crispo A., et al., Insomnia in maintenance haemodialysis patients, Nephrol. Dial. Transplant., 2002, 17, 852–856[Crossref]
  • [12] Di Iorio B., Bartiromo M., Cesare M.C., De Santo R.M., Do sleep disorders start in dialysis or in early chronic kidney disease?, Nephrol. Dial. Transplant., 2006, 21, 1731[Crossref]
  • [13] De Santo R.M., Bartiromo M., Cesare C.M., Cirillo M., Sleep disorders occur very early in chronic kidney disease, J. Nephrol., 2008, 21, S59–65
  • [14] Sabbatini M., Pisani A., Crispo A., et al., Renal transplantation and sleep: a new life is not enough, J. Nephrol., 2008, 21, S97–101
  • [15] Sabbatini M., Crispo A., Pisani A., et al., Sleep quality in renal transplant patients: a never investigated problem, Nephrol. Dial. Transplant., 2005, 20, 194–198[Crossref]
  • [16] Leger D., Scheuermaier K., Philip P., Paillard M., Guilleminault C., SF-36: evaluation of quality of life in severe and mild insomniacs compared with good sleepers, Psychosom. Med., 2001, 63, 49–55 [Crossref]
  • [17] Han S.Y., Yoon J.W., Jo S.K., et al., Insomnia in diabetic hemodialysis patients. Prevalence and risk factors by a multicenter study, Nephron., 2002, 92, 127–132[Crossref]
  • [18] Kimmel P.L., Patel S.S., Quality of life in patients with chronic kidney disease: focus on end-stage renal disease treated with hemodialysis, Semin. Nephrol., 2006, 26, 68–79[Crossref]
  • [19] Unruh M.L., Buysse D.J., Dew M.A., et al., Sleep quality and its correlates in the first year of dialysis, Clin. J. Am. Soc. Nephrol., 2006, 1, 802–810[Crossref]
  • [20] Bastien C.H., Vallières A., Morin C.M., Validation of the Insomnia Severity Index as an outcome measure for insomnia research, Sleep. Med., 2001, 2, 297–307[Crossref]
  • [21] Diagnostic Classification Steering Committee of the American Sleep Disorders Association, The International Classification of Sleep Disorders: Diagnostic and Coding Manual, Rochester, MN, 1990
  • [22] Perl J., Unruh M.L., Chan C.T., Sleep disorders in end-stage renal disease: ‘Markers of inadequate dialysis’?, Kidney. Int., 2006, 70, 1687–1693[Crossref]
  • [23] Sabry A.A., Abo-Zenah H., Wafa E., et al., Sleep disorders in hemodialysis patients, Saudi. J. Kidney. Dis. Transpl., 2010, 21, 300–305
  • [24] Al-Jahdali H.H., Khogeer H.A., Al-Qadh W.A., et al., Insomnia in chronic renal patients on dialysis in Saudi Arabia, J. Circadian. Rhythms., 2010, 8, 7[Crossref]
  • [25] Pai M.F., Hsu S.P., Yang S.Y., Ho T.I., Lai C.F., Peng Y.S., Sleep disturbance in chronic hemodialysis patients: the imact of depression and anemia, Ren. Fail., 2007, 29, 673–677[Crossref][WoS]
  • [26] Chiu Y.L., Chuang Y.F., Fang K.C., et al., Higher systemic inflammation is associated with poorer sleep quality in stable haemodialysis patients, Nephrol. Dial. Transplant., 2009, 24, 247–251[Crossref]
  • [27] Holley J.L., Nespor S., Rault R., A comparison of reported sleep disorders inpatients on chronic hemodialysis and continuous peritoneal dialysis, Am. J. Kidney. Dis., 1992, 19, 156–161 [Crossref]
  • [28] Molnar M.Z., Novak M., Musci I., Sleep disorders and quality of life in renal transplant recipients, Int. Urol. Nephr., 2009, 41, 373–382[Crossref][WoS]
  • [29] Kovacs A.Z., Molnar M.Z., Szeifert L., et al., Sleep disorders, depressive symptoms and health-related quality of life - a cross-sectional comparasion between kidney transplant recipients and waitlisted patients on maintenance dialysis, Nephrol. Dial. Transplant., 2011, 26, 1058–1065[Crossref]
  • [30] De Santo R.M., Lucidi F., Violani C., Di Iorio B.R., Sleep disorders in hemodialyzed patients -the role of comorbidities, Int. J. Artif. Organs., 2005, 28, 557–565
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