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2012 | 7 | 1 | 91-94
Tytuł artykułu

Double-trouble: An unusual case of two simultaneous arterial thromboses in thrombophilia

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Multiple arterial and venous thromboses are usually related to thrombophilia or antiphospholipid syndrome. Recurrent pulmonary embolism strongly indicates the presence of genetic or acquired thrombophilic factors. Simultaneous double arterial in situ thromboses are unusual, even in thrombophilic conditions. Simultaneous occurrence of pulmonary embolism and cerebrovascular ischaemic insult are highly indicative of existence of patent foramen ovale. We present herein a patient with the double simultaneous arterial thromboses as the manifestation of thrombophilia (heterozygous for methylenetetrahydrofolate-reductase (MTHFR) C677T gene mutation). There was no patent foramen ovale suspected upon the patient’s admittance to hospital. To the best of our knowledge there have been no similar cases presented to date.
Wydawca
Czasopismo
Rocznik
Tom
7
Numer
1
Strony
91-94
Opis fizyczny
Daty
wydano
2012-02-01
online
2011-11-24
Twórcy
  • Department of Cardiology, University Clinical Hospital Center Bezanijska Kosa, 11000, Belgrade, Serbia
autor
  • Department of Cardiology, University Clinical Hospital Center Bezanijska Kosa, 11000, Belgrade, Serbia
autor
  • Department of Cardiology, University Clinical Hospital Center Bezanijska Kosa, 11000, Belgrade, Serbia
Bibliografia
  • [1] Goldhaber S.Z. Epidemiology of pulmonary embolism and deep vein thrombosis. In: Bloom A.L., Forbes C.D., Thomas D.P., Tuddenham E.G.D. (eds) Hemostasis and Thrombosis, 3rd ed. Edinburgh, UK: Churchill Livingstone, 2007, pp 1327–1333
  • [2] Bezemer I.D., Doggen C.J., Vos H.L., Rosendaal F.R. No association between the common MTHFR 677C-[T polymorphism and venous thrombosis: results from the MEGA study. Arch Intern Med., 2007, 167, 497–501 http://dx.doi.org/10.1001/archinte.167.5.497[Crossref][WoS]
  • [3] Charafeddine K.M., Mahfouz R.A., Ibrahim G.Y., Taher A.T., Hoballah J.J., Taha A.M. Massive pulmonary embolism associated with Factor V Leiden, prothrombin, and methylenetetrahydrofolate reductase gene mutations in a young patient on oral contraceptive pills: a case report. Clin Appl Thromb Hemost., 2010, 16, 594–598 http://dx.doi.org/10.1177/1076029609334629[WoS][Crossref]
  • [4] Glueck C.J., Wang P. Ocular vascular thrombotic events: a diagnostic window to familial thrombophilia (compound factor V Leiden and prothrombin gene heterozygosity) and thrombosis. Clin Appl Thromb Hemost., 2009, 15, 12–18 http://dx.doi.org/10.1177/1076029608321438[Crossref][WoS]
  • [5] Ivanov P., Komsa-Penkova R., Kovacheva K. Impact of thrombophilic genetic factors on pulmonary embolism: early onset and recurrent incidences. Lung., 2008, 186, 27–36 http://dx.doi.org/10.1007/s00408-007-9061-7[WoS][Crossref]
  • [6] Dixon T., Panda M., Desbiens N. The simultaneous occurrence of deep vein thrombosis and pulmonary and arterial embolization. J Gen Intern Med., 2007, 22, 1040–1041 http://dx.doi.org/10.1007/s11606-007-0169-5[Crossref][WoS]
  • [7] Torbicki A., Perrier A., Konstantinides S., Agnelli G., Galiè N., Pruszczyk P., et al. ESC Committee for Practice Guidelines (CPG). Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur Heart J., 2008, 29, 2276–315 http://dx.doi.org/10.1093/eurheartj/ehn475[Crossref]
  • [8] Kuisma M., Alaspaa A. Out of Hospital Cardiac Arrests of Non-Cardiac Origin: Epidemiology and Outcome. Eur Heart J., 1998, 18, 1122–1128
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11536-011-0110-5
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