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2012 | 7 | 1 | 25-29
Tytuł artykułu

Alteration of secretory IgA in human breast milk and stool samples after the intake of a probiotic - report of 2 cases

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Only a few studies reveal immunological changes in breast milk after the intake of probiotic and none focus on secretory IgA (sIgA). The aim our report was to investigate the levels of sIgA in human breast milk and stools before and after 4 weeks of probiotic intake in a patient with ulcerative colitis (UC) and a control. The study included 2 lactating women: 1 with UC and 1 control. Both received daily 3.75 billion viable Lactobacillus bulgaricus for 28 days. SIgA was measured in breast milk and stools before and after the probiotic intake. The concentration of sIgA in breast milk before the probiotic intake in UC was 408.5 vs 137.4 µg/ml in contol. Fecal sIgA in UC was 420 vs 274 µg/ml in control. After 28 days of probiotic intake there was a decrease in breast milk sIgA in UC but an increase in control - 266.7 vs 914 µg/ml respectively. There was an increase in fecal sIgA both in UC and control - 674.4 vs 1033 µg/ml. It is tempting to speculate that the different sIgA secretion towards the probiotic may be a result of an altered mucosal immune response in UC.
Wydawca
Czasopismo
Rocznik
Tom
7
Numer
1
Strony
25-29
Opis fizyczny
Daty
wydano
2012-02-01
online
2011-11-24
Twórcy
  • Clinic of Gastroenterology, St. Ivan Rilsky University Hospital, 15 Acad. Ivan Geshov blvd, Sofia, 1431, Bulgaria , petar.k.nikolov@gmail.com
autor
  • Clinic of Clinical Immunology, University Hospital Alexandrovska, Sofia, 1431, POBox 45, Bulgaria
Bibliografia
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11536-011-0104-3
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