Effect of Giardia duodenalis in protein malnourished and renourished mice

• Autorzy: Geeta Shukla , Ramandeep Sidhu
• Języki publikacji: EN

Abstrakty

EN

The present study was designed to delineate the effect of Giardia duodenalis in malnourished and renourished BALB/c mice. Control and renourished mice were fed with a standard pellet diet while malnourished mice were fed with a low protein (4.3 %) diet both before and after being challenged orally with actively growing G. duodenalis trophozoites. It was observed that malnourished mice had a greater severity and longer duration of Giardia infection compared with renourished mice. These malnourished mice also had less body mass but higher cyst and trophozoite counts. Malnourished mice infected with Giardia had significantly decreased level of total serum proteins, albumin, globulins, hemoglobin, leukocyte, and differential leukocyte counts compared with renourished mice. From the data it is concluded that protein malnutrition profoundly affects the anthropometric and physiological parameters of the body indicating greater susceptibility and severity of the disease.

Słowa kluczowe

EN

Giardia duodenalis; Giardiasis; Malnutrition; Renourished

• Czasopismo: Open Medicine
• Rocznik: 2011
• Tom: 6
• Numer: 6
• Strony: 762-769

Daty

wydano

2011-12-01

online

2011-10-08

Twórcy

autor

Geeta Shukla

• Department of Microbiology, Panjab University, Chandigarh, 160014, India,

autor

Ramandeep Sidhu

• Department of Microbiology, Panjab University, Chandigarh, 160014, India

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Identyfikatory

DOI

10.2478/s11536-011-0078-1