PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
Czasopismo
2011 | 6 | 2 | 152-157
Tytuł artykułu

Prognosis of thyroid function after hemithyroidectomy

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Identify criteria and create a risk scoring system to predict hypothyroidism after hemithyroidectomy. We have retrospectively studied 216 cases of patients with goiter who had undergone hemithyroidectomy from January 2002 to December 2007 at Vilnius University Hospital Santariškių Klinikos. Patients were divided into two groups according to their thyroid function after hemithyroidectomy: 168 (77.8%) patients’ thyroid function was normal (group A), 48 (22.2%) patients had symptoms of hypothyroidism (group B). The relationship between groups and parameters such as patients’ sex, age, patient’s weight, preoperative serum thyroid-stimulating hormone (TSH) level, weight of the remnant gland, ratio of the remaining thyroid gland weight to patient’s weight was statistically analysed. The patients’ mean age was 41.6 ± 14.1 years in group A and 52.9 ± 13.9 years in group B (p=0.0002). The mean preoperative TSH level was 0.79 ± 0.5 mU/L in group A, compared with 1.42 ± 1.00 mU/L in group B (p= 0.005). The mean ratio of the remaining thyroid gland weight to patient’s weight was 0.102 ± 0.053 g/kg in group A and 0.063 ± 0.027 g/kg in group B (p=0.04). The groups did not establish a significant difference between patients’ sex, patient’s weight or weight of the remaining gland. Patient’s age, preoperative serum TSH level, ratio of the remaining thyroid gland weight to patient’s weight is the main factors of hypothyroidism after hemithyroidectomy. A risk scoring system was created to predict hypothyroidism after hemithyroidectomy before the operation.
Słowa kluczowe
Wydawca

Czasopismo
Rocznik
Tom
6
Numer
2
Strony
152-157
Opis fizyczny
Daty
wydano
2011-04-01
online
2011-02-17
Twórcy
autor
  • Center of Abdominal surgery, Vilnius University Hospital Santariškių Klinikos, LT-08661, Vilnius, Lithuani
  • Center of Abdominal surgery, Vilnius University Hospital Santariškių Klinikos, LT-08661, Vilnius, Lithuani, dkazanavicius@gmail.com
  • Center of Abdominal surgery, Vilnius University Hospital Santariškių Klinikos, LT-08661, Vilnius, Lithuani
autor
  • Center of Abdominal surgery, Vilnius University Hospital Santariškių Klinikos, LT-08661, Vilnius, Lithuani
autor
  • Center of Abdominal surgery, Vilnius University Hospital Santariškių Klinikos, LT-08661, Vilnius, Lithuani
autor
  • Center of Abdominal surgery, Vilnius University Hospital Santariškių Klinikos, LT-08661, Vilnius, Lithuani
Bibliografia
  • [1] Hegedus L. Clinical practice: the thyroid nodule, N Engl J Med. - 2004, vol. 351, no. 17, p. 1764–1771 http://dx.doi.org/10.1056/NEJMcp031436[Crossref]
  • [2] Ross D.S. Nonpalpable thyroid nodules: managing an epidemic, J Clin Endocrinol Metab. - 2002, vol. 87, no. 5, p. 1938–1940 http://dx.doi.org/10.1210/jc.87.5.1938[Crossref]
  • [3] Cooper D.S., Doherty G.M., Haugen B.R. et al. Management guidelines for patients with thyroid nodules and differentiated thyroid cancer, Thyroid. - 2006, vol. 16, no. 2, p.109–142 http://dx.doi.org/10.1089/thy.2006.16.109[Crossref][WoS]
  • [4] Gharib H., Papini E., Valcavi R. … et al. American Assosiation of Clinical Endocrinologists and Associazione Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules, Endocr Pract. - 2006, vol. 12, no. 1, p. 63–102
  • [5] Gharib H., Mazzaferri E.L. Thyroxine suppressive therapy in patients with nodular thyroid disease, Ann Intern Med. - 1998, vol. 128, no. 5, p. 386–394
  • [6] Moon H.G., Jung E.J., Park S.T. et al. Thyrotropin level and thyroid volume for prediction of hypothyroidism following hemithyroidectomy in an Asian patient cohort, World J Surg. - 2008, vol. 32, no. 11, p. 2503–2508 http://dx.doi.org/10.1007/s00268-008-9717-3[WoS][Crossref]
  • [7] Sawin C.T. Subclinical hyperthyroidism and atrial fibrillation, Thyroid. - 2002, vol. 12, no. 6, p. 501–503 http://dx.doi.org/10.1089/105072502760143881[Crossref]
  • [8] Al-Abadi A.C. Subclinical thyrotoxicosis, Postgrad Med J. - 2001, vol. 77, no. 903, p. 29–32 http://dx.doi.org/10.1136/pmj.77.903.29[Crossref]
  • [9] McHenry C.R., Slusarczyk S.J. Hypothyroidisim following hemithyroidectomy: incidence, risk factors, and management, Surgery. - 2000, vol. 128, no. 6, p. 994–998 http://dx.doi.org/10.1067/msy.2000.110242[Crossref]
  • [10] Berglund J., Bondeson L., Christensen S.B., Tibblin S. The influence of different degrees of chronic lymphocytic thyroiditis on thyroid function after surgery for benign, non-toxic goitre, Eur J Surg. - 1991, vol. 157, no. 4, p. 257–260
  • [11] Koh Y.W., Lee S.W., Choi E.C. et al. Prediction of hypothyroidism after hemithyroidectomy: a biochemical and pathological analysis, Eur Arch Otorhinolaryngol. - 2008, vol. 265, no. 4, p. 453–457 http://dx.doi.org/10.1007/s00405-007-0513-8[Crossref]
  • [12] Žeromskas P. Skydliaukės dydžio ir jos likučio po operacijos nustatymas: daktaro disertacija. - Vilnius, 2000. - 102 p
  • [13] Piper H.G., Bugis S.P., Wilkins G.E. et al. Detecting and defining hypothyroidism after hemithyroidectomy, Am J Surg. - 2005, vol. 189, no. 5, p. 587–591. (discussion 591) http://dx.doi.org/10.1016/j.amjsurg.2005.01.038[Crossref]
  • [14] Hedman I., Jansson S., Lindberg S. Need for thyroxine in patients lobectomised for benign thyroid disease as assessed by follow-up on average 15 years after surgery, Acta Chir Scand. - 1986, vol. 152, p. 481–486
  • [15] Mandel S.J. A 64-year-old woman with a thyroid nodule, JAMA. - 2004, vol. 292, no. 21, p. 2632–2642 http://dx.doi.org/10.1001/jama.292.21.2632[Crossref]
  • [16] Lombardi G., Panza N., Lupoli G. et al. Study of the pituitary-thyroid axis in euthyroid goiter after partial thyroidectomy, J Endocrinol Invest. - 1983, vol. 6, no. 6, p. 485–487 [Crossref]
  • [17] Buchanan M.A., Lee D. Thyroid auto-antibodies, lymphocytic infiltration and the development of post-operative hypothyroidism following hemithyroidectomy for non-toxic nodular goitre, J R Coll Surg Edinb. - 2001, vol. 46, no. 2, p. 86–90
  • [18] Miller F.R., Paulson D., Prihoda T.J., Otto R.A. Risk factors for the development of hypothyroidism after hemithyroidectomy, Arch Otolaryngol Head Neck Surg. - 2006, vol. 132, no. 1, p. 36–38 http://dx.doi.org/10.1001/archotol.132.1.36[Crossref]
  • [19] Bang U., Blichert-Toft M., Petersen P.H. et al. Thyroid function after resection for nontoxic goitre with special reference to thyroid lymphocytic aggregation and circulating thyroid autoantibodies, Acta Endocrinol (Copenh). - 1985, vol. 109, p. 214–219
  • [20] Seiberling K.A., Dutra J.C., Bajaramovic S. Hypothyroidism following hemithyroidectomy for benign nontoxic thyroid disease, Ear Nose Throat J. - 2007, vol. 86, no. 5, p. 295–299
  • [21] Su S.Y., Serpell J. Es16p hypothyroidism following hemithyroidectomy, ANZ J Surg. - 2007, vol. 77,suppl. 1, p. A24 http://dx.doi.org/10.1111/j.1445-2197.2007.04118_16.x[Crossref]
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11536-010-0064-z
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.