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2010 | 5 | 4 | 426-430
Tytuł artykułu

Combined treatment and survival of medullary thyroid carcinoma patients

Treść / Zawartość
Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The aim of this study is to analyze the impact of combined treatment (thyroidectomy and radiotherapy and radioactive iodine treatment) on patients’ long-term survival with medullary thyroid carcinoma. This is a retrospective study of 59 patients treated from 1977 to 2006 for medullary carcinoma at the Institute of Oncology in Vilnius, Lithuania. Survival was estimated by the Kaplan-Meier method. Univariate and multivariate Cox proportional hazard models were used to explore the association of prognostic factors with long-term survival. The survival of MTC patients was 88.0% (95% CI 68.0–88.9), 67.9% (95% CI 52.3–79.4) and 60.5% (95% CI 43.2–74.0), respectively, 5, 10 and 15 years after diagnosis. In survival analysis, only the type of surgery and lymph node involvement were found to be significant prognostic factors. The results of this study suggest that treatment with radioiodine and external beam radiotherapy do not improve significantly the long-term survival of surgically treated MTC patients.
Wydawca
Czasopismo
Rocznik
Tom
5
Numer
4
Strony
426-430
Opis fizyczny
Daty
wydano
2010-08-01
online
2010-05-30
Twórcy
  • Institute of Oncology, Vilnius University, Clinic of conservative tumour therapy, Santariskiu 1, LT-08660, Vilnius, Lithuania
  • Institute of Oncology, Vilnius University, Clinic of conservative tumour therapy, Santariskiu 1, LT-08660, Vilnius, Lithuania
  • Institute of Oncology, Vilnius University, Scientific Research Centre, P. Baublio 3B, LT-08406, Vilnius, Lithuania , giedre.smailyte@vuoi.lt
Bibliografia
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.-psjd-doi-10_2478_s11536-010-0023-8
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