Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2010 | 5 | 3 | 375-380
Tytuł artykułu

Fluoride bioavailability in saliva using DENTTABS® compared to dentifrice

Treść / Zawartość
Warianty tytułu
Języki publikacji
It was the aim of this study to assess fluoride retained in saliva after use of fluoride-containing tablet DENTTABS® compared to toothpaste containing amine fluoride. Four subjects (2 normal saliva secretors, 1 slow secretor, and 1 fast secretor) participated in this crossover study comparing DENTTABS® and ELMEX®. After baseline sample collection, calibrated study personnel brushed the subjects’ teeth with the assigned product for 3 minutes. Saliva samples were taken at baseline (T0), immediately after brushing (T1) and then 10 (T2), 25 (T3) and 85 (T4) minutes post-brushing. The amount of saliva collected was measured, and the fluoride content was analysed. All 4 subjects repeated all study cycles 5 times. Statistical analysis was done using the Mann-Whitney-U test and Spearman correlation. The fluoride retention was significantly higher after brushing with DENTTABS® at T1 and T2. There was a correlation between individual salivary flow rate and the F- content. Flow rate in g/min ranged from 1.1 to 3.8 at T1 and from 0.2 to 1.1 at T4 with much higher F- retention in slow secreting cycles. The saliva fluoride clearance kinetics of two equal amounts of fluoride-containing oral hygiene products demonstrate higher retention for DENTTABS®.
Słowa kluczowe

Opis fizyczny
  • Faculty of Dental Medicine, University of Witten/Herdecke, Alfred Herrhausenstrasse 50, 58448, Witten, Germany
  • Faculty of Dental Medicine, University of Witten/Herdecke, Alfred Herrhausenstrasse 50, 58448, Witten, Germany,
  • Faculty of Dental Medicine, University of Witten/Herdecke, Alfred Herrhausenstrasse 50, 58448, Witten, Germany
  • [1] Dawes, C., Weatherell, J. A., Kinetics of fluoride in the oral fluids. J. Dent. Res., 1990, 69 Spec No, 638–644; discussion 682–633
  • [2] Featherstone, J. D., The science and practice of caries prevention. J. Am. Dent. Assoc., 2000, 131, 887–899 [Crossref]
  • [3] Margolis, H. C., Moreno, E. C., Physicochemical perspectives on the cariostatic mechanisms of systemic and topical fluorides. J. Dent. Res., 1990, 69 Spec No, 606–613; discussion 634–606
  • [4] Bruun, C., Givskov, H., Thylstrup, A., Whole saliva fluoride after toothbrushing with NaF and MFP dentifrices with different F concentrations. Caries Res., 1984, 18, 282–288[Crossref]
  • [5] Aasenden, R., Brudevold, F., Richardson, B., Clearance of fluoride from the mouth after topical treatment or the use of a fluoride mouthrinse. Arch. Oral Biol., 1968, 13, 625–636[Crossref]
  • [6] Bijella, M. F., Brighenti, F. L., Buzalaf, M. A., Fluoride kinetics in saliva after the use of a fluoride-containing chewing gum. Braz. Oral Res., 2005, 19, 256–260[Crossref]
  • [7] Oliveby, A., Ekstrand, J., Lagerlof, F., Effect of salivary flow rate on salivary fluoride clearance after use of a fluoride-containing chewing gum. Caries Res., 1987, 21, 393–401[Crossref]
  • [8] Hedman, J., Sjoman, R., Sjostrom, I., Twetman, S., Fluoride concentration in saliva after consumption of a dinner meal prepared with fluoridated salt. Caries Res., 2006, 40, 158–162[Crossref]
  • [9] Sjogren, K., Birkhed, D., Persson, L. G., Noren, J. G., Salivary fluoride clearance after a single intake of fluoride tablets and chewing gums in children, adults, and dry mouth patients. Scand. J. Dent. Res., 1993, 101, 274–278
  • [10] Petersson, L. G., Arvidsson, I., Lynch, E., Engstrom, K., Twetman, S., Fluoride concentrations in saliva and dental plaque in young children after intake of fluoridated milk. Caries Res., 2002, 36, 40–43[Crossref]
  • [11] Böshagen, C., Eifler, H., Gängler, P., Klinische Bewertung der Mundhygieneeffektivität einer Zahnputztablette. Zahnarzt und Praxis, 2005, 8, 420–424
  • [12] Schipper, R. G., Silletti, E., Vingerhoeds, M. H., Saliva as research material: biochemical, physicochemical and practical aspects. Arch. Oral Biol., 2007, 52, 1114–1135[WoS][Crossref]
  • [13] Newbrun, E., Topical fluorides in caries prevention and management: a North American perspective. J. Dent. Educ., 2001, 65, 1078–1083
  • [14] de Almeida Pdel, V., Gregio, A. M., Machado, M. A., de Lima, A. A., Azevedo, L. R., Saliva composition and functions: a comprehensive review. J. Contemp. Dent. Pract., 2008, 9, 72–80
  • [15] Jenkins, G. N., Saliva, in The Physiology and biochemistry of the Mouth., Jenkins, G. N., Editor. Blackwell Scientific Publications, Oxford, London, Edinburgh, 1978
  • [16] Heijnsbroek, M., Gerardu, V. A., Buijs, M. J., van Loveren, C., ten Cate, J. M., Timmerman, M. F., et al., Increased salivary fluoride concentrations after post-brush fluoride rinsing not reflected in dental plaque. Caries Res., 2006, 40, 444–448[Crossref]
  • [17] Ten Cate, J. M., Buijs, M. J., Miller, C. C., Exterkate, R. A., Elevated fluoride products enhance remineralization of advanced enamel lesions. J. Dent. Res., 2008, 87, 943–947[Crossref][WoS]
  • [18] Duckworth, R. M., Morgan, S. N., Oral fluoride retention after use of fluoride dentifrices. Caries Res., 1991, 25, 123–129[Crossref]
  • [19] Duckworth, R. M., Stewart, D., Effect of mouthwashes of variable NaF concentration but constant NaF content on oral fluoride retention. Caries Res., 1994, 28, 43–47[Crossref]
  • [20] Duckworth, R. M., Knoop, D. T., Stephen, K. W., Effect of mouthrinsing after toothbrushing with a fluoride dentifrice on human salivary fluoride levels. Caries Res., 1991, 25, 287–291[Crossref]
  • [21] Issa, A. I., Toumba, K. J., Oral fluoride retention in saliva following toothbrushing with child and adult dentifrices with and without water rinsing. Caries Res., 2004, 38, 15–19[Crossref]
  • [22] Attin, T., Hellwig, E., Salivary fluoride content after toothbrushing with a sodium fluoride and an amine fluoride dentifrice followed by different mouthrinsing procedures. J. Clin. Dent., 1996, 7, 6–8
Typ dokumentu
Identyfikator YADDA
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.